标题
Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
作者
关键词
-
出版物
NEURON
Volume 111, Issue 8, Pages 1222-1240.e9
出版商
Elsevier BV
发表日期
2023-03-13
DOI
10.1016/j.neuron.2023.02.019
参考文献
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- (2022) Dylan V. Neel et al. IMMUNOLOGICAL REVIEWS
- Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis
- (2022) Chi G. Weindel et al. CELL
- p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
- (2021) Maya Maor-Nof et al. CELL
- Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation
- (2021) Weiwei Xia et al. Cell Death & Disease
- Early Axonal Dysfunction of the Peripheral Nervous System Influences Disease Progression of ALS: Evidence From Clinical Neuroelectrophysiology
- (2021) Huiyan Yu et al. Frontiers in Neurology
- A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation
- (2021) Zizhen Yao et al. CELL
- Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells
- (2021) Megan H. Orzalli et al. IMMUNITY
- FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply
- (2021) Himanish Basu et al. JOURNAL OF CELL BIOLOGY
- Caspase‐3‐mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway
- (2021) Ziwen Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner
- (2021) Michael MacLean et al. Journal of Neuroinflammation
- Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
- (2021) Valentina N. Lagomarsino et al. NEURON
- Gasdermin-E-mediated pyroptosis participates in the pathogenesis of Crohn’s disease by promoting intestinal inflammation
- (2021) Gao Tan et al. Cell Reports
- Mitochondria in Neuronal Health: From Energy Metabolism to Parkinson's Disease
- (2021) Hariharan Murali Mahadevan et al. Advanced Biology
- Gasdermin E mediates photoreceptor damage by all-trans-retinal in the mouse retina
- (2021) Binxiang Cai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Comparative cellular analysis of motor cortex in human, marmoset and mouse
- (2021) Trygve E. Bakken et al. NATURE
- Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons
- (2021) Nicole J. Yang et al. NATURE NEUROSCIENCE
- C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import
- (2020) Lindsey R Hayes et al. eLife
- Gasdermin E suppresses tumour growth by activating anti-tumour immunity
- (2020) Zhibin Zhang et al. NATURE
- FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
- (2020) Jun Jacob Hu et al. NATURE IMMUNOLOGY
- TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
- (2020) Chien-Hsiung Yu et al. CELL
- Succination inactivates gasdermin D and blocks pyroptosis
- (2020) Fiachra Humphries et al. SCIENCE
- MAP4K4 Activation Mediates Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis
- (2019) Chen Wu et al. Cell Reports
- Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
- (2019) Junhui Yu et al. Cell Death & Disease
- Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM
- (2019) Michael Carty et al. IMMUNITY
- C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo
- (2019) So Yoen Choi et al. NATURE NEUROSCIENCE
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
- (2019) Corey Rogers et al. Nature Communications
- TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response
- (2019) Peng Wang et al. PLoS Genetics
- Mitochondria as multifaceted regulators of cell death
- (2019) Florian J. Bock et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Transcriptome–pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS
- (2018) Florian Krach et al. ACTA NEUROPATHOLOGICA
- Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
- (2018) Nathalia M. de Vasconcelos et al. CELL DEATH AND DIFFERENTIATION
- Cortical Neurotoxic Astrocytes with Early ALS Pathology and miR-146a Deficit Replicate Gliosis Markers of Symptomatic SOD1G93A Mouse Model
- (2018) Cátia Gomes et al. MOLECULAR NEUROBIOLOGY
- Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris
- (2018) et al. NATURE
- Mitochondria modulate programmed neuritic retraction
- (2018) Sergei V. Baranov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
- (2017) Yupeng Wang et al. NATURE
- Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions
- (2017) Mei-Yao Lin et al. NEURON
- Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
- (2017) Corey Rogers et al. Nature Communications
- The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD
- (2017) Brian D. Freibaum et al. Frontiers in Molecular Neuroscience
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
- (2016) Wenzhang Wang et al. NATURE MEDICINE
- Pathological Axonal Death through a MAPK Cascade that Triggers a Local Energy Deficit
- (2015) Jing Yang et al. CELL
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- LC3 binds externalized cardiolipin on injured mitochondria to signal mitophagy in neurons
- (2014) Charleen T Chu et al. Autophagy
- Generation of Functional Human Pancreatic β Cells In Vitro
- (2014) Felicia W. Pagliuca et al. CELL
- Local Pruning of Dendrites and Spines by Caspase-3-Dependent and Proteasome-Limited Mechanisms
- (2014) A. Erturk et al. JOURNAL OF NEUROSCIENCE
- Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes
- (2014) Yves Maury et al. NATURE BIOTECHNOLOGY
- Wallerian degeneration: an emerging axon death pathway linking injury and disease
- (2014) Laura Conforti et al. NATURE REVIEWS NEUROSCIENCE
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease
- (2014) Elizabeth B. Moloney et al. Frontiers in Neuroscience
- Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
- (2013) Charleen T. Chu et al. NATURE CELL BIOLOGY
- Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
- (2013) Yingsha Zhang et al. NEURON
- Mitochondrial Trafficking in Neurons
- (2013) T. L. Schwarz Cold Spring Harbor Perspectives in Biology
- Programmed Cell Death in Parkinson's Disease
- (2013) K. Venderova et al. Cold Spring Harbor Perspectives in Medicine
- Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo
- (2011) S. T. Papadeas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Forebrain overexpression of α-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption
- (2009) Youngshin Lim et al. EXPERIMENTAL NEUROLOGY
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