Gasdermin E suppresses tumour growth by activating anti-tumour immunity

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

(2019) Corey Rogers et al.   Nature Communications

The role of pyroptosis in cancer: pro-cancer or pro-“host”?

(2019) Xiaojing Xia et al.   Cell Death & Disease

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death

(2018) Hiroto Kambara et al.   Cell Reports

Cryo-EM structure of the gasdermin A3 membrane pore

(2018) Jianbin Ruan et al.   NATURE

Efferocytosis in the tumor microenvironment

(2018) Thomas A. Werfel et al.   Seminars in Immunopathology

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

(2017) Corey Rogers et al.   Nature Communications

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

(2016) Tania Løve Aaes et al.   Cell Reports

A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed

(2015) Rahul Palchaudhuri et al.   Cell Reports

DFNA5, a Gene Involved in Hearing Loss and Cancer: A Review

(2014) Ken Op de Beeck et al.   ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

A Genome-wide siRNA Screen Identifies Proteasome Addiction as a Vulnerability of Basal-like Triple-Negative Breast Cancer Cells

(2013) Fabio Petrocca et al.   CANCER CELL

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Death by a Thousand Cuts: Granzyme Pathways of Programmed Cell Death

(2008) Dipanjan Chowdhury et al.   Annual Review of Immunology