CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions
出版年份 2023 全文链接
标题
CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions
作者
关键词
-
出版物
NATURE IMMUNOLOGY
Volume 24, Issue 3, Pages 452-462
出版商
Springer Science and Business Media LLC
发表日期
2023-02-24
DOI
10.1038/s41590-023-01430-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A non-canonical tricarboxylic acid cycle underlies cellular identity
- (2022) Paige K. Arnold et al. NATURE
- PERK is a critical metabolic hub for immunosuppressive function in macrophages
- (2022) Lydia N. Raines et al. NATURE IMMUNOLOGY
- Agonistic CD40 Antibodies in Cancer Treatment
- (2021) Dijana Djureinovic et al. Cancers
- Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity
- (2021) Giusy Di Conza et al. NATURE IMMUNOLOGY
- Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion
- (2020) Yi-Ru Yu et al. NATURE IMMUNOLOGY
- Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle
- (2019) Wan-Chen Cheng et al. NATURE IMMUNOLOGY
- The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance
- (2019) Nicola Vannini et al. Cell Stem Cell
- Re-education of macrophages as a therapeutic strategy in cancer
- (2019) Joanna Kowal et al. Immunotherapy
- Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages
- (2019) David P. De Souza et al. JOURNAL OF CLINICAL INVESTIGATION
- Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses
- (2019) P. Kent Langston et al. NATURE IMMUNOLOGY
- Hyperpolarized [1-13C]lactate flux increased in the hippocampal region in diabetic mice
- (2019) Young-Suk Choi et al. Molecular Brain
- Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase
- (2019) Mario A. Lauterbach et al. IMMUNITY
- Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy
- (2019) Abhishek S. Kashyap et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis
- (2018) Ajit S. Divakaruni et al. Cell Metabolism
- Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation
- (2018) Brenda Raud et al. Cell Metabolism
- Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity
- (2018) Sabine Hoves et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lipopolysaccharide-Induced Dephosphorylation of AMPK-Activated Protein Kinase Potentiates Inflammatory Injury via Repression of ULK1-Dependent Autophagy
- (2018) Kerui Fan et al. Frontiers in Immunology
- A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation
- (2018) Niamh C. Williams et al. Frontiers in Immunology
- Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer
- (2017) E A Hanse et al. ONCOGENE
- Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages
- (2016) Elizabeth Liu et al. INFECTION AND IMMUNITY
- Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1α-dependent
- (2016) Lingling Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
- (2016) Steven Zhao et al. Cell Reports
- Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
- (2016) Anthony J Covarrubias et al. eLife
- Metabolic communication in tumors: a new layer of immunoregulation for immune evasion
- (2016) Ping-Chih Ho et al. Journal for ImmunoTherapy of Cancer
- Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
- (2015) Zachary T. Schug et al. CANCER CELL
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- The interplay of histone modifications - writers that read
- (2015) T. Zhang et al. EMBO REPORTS
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- Immunometabolism governs dendritic cell and macrophage function
- (2015) Luke A.J. O’Neill et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Citrate – new functions for an old metabolite
- (2014) Vito Iacobazzi et al. BIOLOGICAL CHEMISTRY
- Immune-Based Antitumor Effects of BRAF Inhibitors Rely on Signaling by CD40L and IFN
- (2014) P.-C. Ho et al. CANCER RESEARCH
- Tumor-Associated Macrophages: From Mechanisms to Therapy
- (2014) Roy Noy et al. IMMUNITY
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance
- (2012) Ping-Chih Ho et al. NATURE IMMUNOLOGY
- Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
- (2011) Gerritje J.W. van der Windt et al. IMMUNITY
- CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
- (2011) G. L. Beatty et al. SCIENCE
- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
- (2009) K. E. Wellen et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now