A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation
出版年份 2018 全文链接
标题
A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation
作者
关键词
-
出版物
Frontiers in Immunology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-02-05
DOI
10.3389/fimmu.2018.00141
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Krebs cycle rewired for macrophage and dendritic cell effector functions
- (2017) Dylan Gerard Ryan et al. FEBS LETTERS
- Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly
- (2017) Mahmoud ElAzzouny et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2Production
- (2017) Zbigniew Zasłona et al. JOURNAL OF IMMUNOLOGY
- ATP citrate lyase is increased in human breast cancer, depletion of which promotes apoptosis
- (2017) Diyu Wang et al. TUMOR BIOLOGY
- BCAT1 controls metabolic reprogramming in activated human macrophages and is associated with inflammatory diseases
- (2017) Adonia E. Papathanassiu et al. Nature Communications
- Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis
- (2017) Lingli Hu et al. Frontiers in Immunology
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Food Fight: Role of Itaconate and Other Metabolites in Antimicrobial Defense
- (2016) Harding H. Luan et al. Cell Metabolism
- Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
- (2016) Vicky Lampropoulou et al. Cell Metabolism
- Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage
- (2016) Beáta Németh et al. FASEB JOURNAL
- Memory CD8 + T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function
- (2016) Maria L. Balmer et al. IMMUNITY
- Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels
- (2016) Thekla Cordes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HIF1α and metabolic reprogramming in inflammation
- (2016) Sarah E. Corcoran et al. JOURNAL OF CLINICAL INVESTIGATION
- Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages
- (2016) Aravind Tallam et al. PLoS One
- Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
- (2016) M. Peng et al. SCIENCE
- N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes
- (2016) A. Prokesch et al. Scientific Reports
- ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
- (2016) Steven Zhao et al. Cell Reports
- IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid
- (2016) Jan Naujoks et al. PLoS Pathogens
- Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
- (2016) Anthony J Covarrubias et al. eLife
- Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation
- (2015) Erika M. Palmieri et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
- (2015) Zachary T. Schug et al. CANCER CELL
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- Acetyl Coenzyme A: A Central Metabolite and Second Messenger
- (2015) Federico Pietrocola et al. Cell Metabolism
- Metabolic reprogramming in macrophages and dendritic cells in innate immunity
- (2015) Beth Kelly et al. CELL RESEARCH
- IRG1 induced by heme oxygenase-1/carbon monoxide inhibits LPS-mediated sepsis and pro-inflammatory cytokine production
- (2015) Md Jamal Uddin et al. Cellular & Molecular Immunology
- Acetyl-CoA and the regulation of metabolism: mechanisms and consequences
- (2015) Lei Shi et al. CURRENT OPINION IN CELL BIOLOGY
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation
- (2015) Gozde Colak et al. MOLECULAR & CELLULAR PROTEOMICS
- SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target
- (2015) Yuya Nishida et al. MOLECULAR CELL
- A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα- and IFNγ-triggered inflammation
- (2014) Vittoria Infantino et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Citrate – new functions for an old metabolite
- (2014) Vito Iacobazzi et al. BIOLOGICAL CHEMISTRY
- ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway
- (2014) Jong-Hyuk Lee et al. FEBS Journal
- Modulation of Ten-Eleven Translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) Expression, α-Ketoglutarate (α-KG), and DNA Hydroxymethylation Levels by Interleukin-1β in Primary Human Chondrocytes
- (2014) Abdul Haseeb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adenosine 5'-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype
- (2014) D. Sag et al. JOURNAL OF IMMUNOLOGY
- Bacterial itaconate degradation promotes pathogenicity
- (2014) Jahminy Sasikaran et al. Nature Chemical Biology
- Glycolytic reprogramming by TLRs in dendritic cells
- (2014) Luke A J O'Neill NATURE IMMUNOLOGY
- TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
- (2014) Bart Everts et al. NATURE IMMUNOLOGY
- The growing landscape of lysine acetylation links metabolism and cell signalling
- (2014) Chunaram Choudhary et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production
- (2014) Bin Wang et al. Nature Communications
- Metabolic Reprograming in Macrophage Polarization
- (2014) Silvia Galván-Peña et al. Frontiers in Immunology
- Inhibition of ATP Citrate Lyase Induces an Anticancer Effect via Reactive Oxygen Species
- (2013) Toshiro Migita et al. AMERICAN JOURNAL OF PATHOLOGY
- ATP-citrate lyase is essential for macrophage inflammatory response
- (2013) Vittoria Infantino et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Citric Acid Cycle and Role of its Intermediates in Metabolism
- (2013) Muhammad Akram CELL BIOCHEMISTRY AND BIOPHYSICS
- Succinate receptor GPR91, a Gαicoupled receptor that increases intracellular calcium concentrations through PLCβ
- (2013) Linda Sundström et al. FEBS LETTERS
- Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species
- (2013) Yingke Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- How Metabolism Generates Signals during Innate Immunity and Inflammation
- (2013) Anne F. McGettrick et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Succinate: a metabolic signal in inflammation
- (2013) Evanna Mills et al. TRENDS IN CELL BIOLOGY
- The TSC-mTOR pathway regulates macrophage polarization
- (2013) Vanessa Byles et al. Nature Communications
- Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
- (2012) B. Everts et al. BLOOD
- ATP-Citrate Lyase: A Key Player in Cancer Metabolism
- (2012) N. Zaidi et al. CANCER RESEARCH
- ATP Citrate Lyase Knockdown Induces Growth Arrest and Apoptosis through Different Cell- and Environment-Dependent Mechanisms
- (2012) N. Zaidi et al. MOLECULAR CANCER THERAPEUTICS
- Prognostic and therapeutic implications of increased ATP citrate lyase expression in human epithelial ovarian cancer
- (2012) YU WANG et al. ONCOLOGY REPORTS
- The mitochondrial citrate carrier: a new player in inflammation
- (2011) Vittoria Infantino et al. BIOCHEMICAL JOURNAL
- Mammalian ACSF3 Protein Is a Malonyl-CoA Synthetase That Supplies the Chain Extender Units for Mitochondrial Fatty Acid Synthesis
- (2011) Andrzej Witkowski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome
- (2011) F. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- 1H NMR-based Metabolomic Profiling in Mice Infected withMycobacterium tuberculosis
- (2011) Ji-Hyun Shin et al. JOURNAL OF PROTEOME RESEARCH
- Non-targeted metabolite profiling in activated macrophage secretion
- (2011) Masahiro Sugimoto et al. Metabolomics
- The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme
- (2011) Chao Peng et al. MOLECULAR & CELLULAR PROTEOMICS
- Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
- (2011) J. Du et al. SCIENCE
- Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
- (2010) C. M. Krawczyk et al. BLOOD
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism
- (2010) Na Zhang et al. Cell Metabolism
- Regulation of Cellular Metabolism by Protein Lysine Acetylation
- (2010) S. Zhao et al. SCIENCE
- Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer
- (2009) Abdullah Yalcin et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- The mitochondrial citrate carrier: Metabolic role and regulation of its activity and expression
- (2009) Gabriele V. Gnoni et al. IUBMB LIFE
- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
- (2009) K. E. Wellen et al. SCIENCE
- Malonyl-CoA, a Key Signaling Molecule in Mammalian Cells
- (2008) David Saggerson Annual Review of Nutrition
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- ATP Citrate Lyase: Activation and Therapeutic Implications in Non-Small Cell Lung Cancer
- (2008) T. Migita et al. CANCER RESEARCH
- A calculated response: control of inflammation by the innate immune system
- (2008) Gregory M. Barton JOURNAL OF CLINICAL INVESTIGATION
- The Proinflammatory Cytokine-Induced IRG1 Protein Associates with Mitochondria
- (2008) Daniel Degrandi et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started