Developing a Multitargeted Anticancer Palladium(II) Agent Based on the His-242 Residue in the IIA Subdomain of Human Serum Albumin

Developing an Anticancer Platinum(II) Compound Based on the Uniqueness of Human Serum Albumin

(2023) Zhenlei Zhang et al.   Journal of Medicinal Chemistry

The coordination modes of (thio)semicarbazone copper(II) complexes strongly modulate the solution chemical properties and mechanism of anticancer activity

(2022) Vivien Pósa et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Developing a Novel Indium(III) Agent Based on Human Serum Albumin Nanoparticles: Integrating Bioimaging and Therapy

(2022) Zhenlei Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper(II) Complexes of Halogenated Quinoline Schiff Base Derivatives Enabled Cancer Therapy through Glutathione-Assisted Chemodynamic Therapy and Inhibition of Autophagy Flux

(2022) Wen-Ying Shen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Developing a Copper(II) Agent Based on His-146 and His-242 Residues of Human Serum Albumin Nanoparticles: Integration To Overcome Cisplatin Resistance and Inhibit the Metastasis of Nonsmall Cell Lung Cancer

(2022) Ming Jiang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparative Studies on DNA-Binding Mechanisms between Enantiomers of a Polypyridyl Ruthenium(II) Complex

(2022) Yanhong Nie et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Novel Target for Limiting VEGF-A (Vascular Endothelial Growth Factor A)–Induced Vascular Permeability

(2022) Joyce Bischoff   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure

(2022) Keishi Yamasaki et al.   Journal of Medicinal Chemistry

Developing a Gallium(III) Agent Based on the Properties of the Tumor Microenvironment and Lactoferrin: Achieving Two-Agent Co-delivery and Multi-targeted Combination Therapy of Cancer

(2022) Tongfu Yang et al.   Journal of Medicinal Chemistry

Selectivity and Targeting of G‐quadruplex Binders Activated by Adaptive Binding and Controlled by Chemical Kinetics

(2021) Bo-Chen Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Developing a Novel Anticancer Gold(III) Agent to Integrate Chemotherapy and Immunotherapy

(2021) Juzheng Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dithiocarbazate-Copper Complexes for Bioimaging and Treatment of Pancreatic Cancer

(2021) Yi Gou et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Uniqueness of Albumin as a Carrier in Nanodrug Delivery

(2021) Alessandra Spada et al.   MOLECULAR PHARMACEUTICS

Therapeutic Targeting of the Tumor Microenvironment

(2021) Leire Bejarano et al.   Cancer Discovery

Versatile delivery systems for non-platinum metal-based anticancer therapeutic agents

(2021) Yi Gou et al.   COORDINATION CHEMISTRY REVIEWS

Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments

(2021) Robert Czarnomysy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Developing a Novel Indium(III) Agent Based on Liposomes to Overcome Cisplatin-Induced Resistance in Breast Cancer by Multitargeting the Tumor Microenvironment Components

(2021) Ming Jiang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Radical-Trapping Antioxidant Activity of Copper and Nickel Bis(Thiosemicarbazone) Complexes Underlies Their Potency as Inhibitors of Ferroptotic Cell Death

(2021) Omkar Zilka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Human Serum Albumin-Based Dual-Agent Delivery Systems for Combination Therapy: Acting against Cancer Cells and Inhibiting Neovascularization in the Tumor Microenvironment

(2020) Zhenlei Zhang et al.   MOLECULAR PHARMACEUTICS

Targeting apoptosis in cancer therapy

(2020) Benedito A. Carneiro et al.   Nature Reviews Clinical Oncology

Innate-adaptive immunity interplay and redox regulation in immune response

(2020) Lizhe Sun et al.   Redox Biology

Anticancer activity of palladium-based complexes against triple-negative breast cancer

(2019) Martin Vojtek et al.   DRUG DISCOVERY TODAY

VEGF in Signaling and Disease: Beyond Discovery and Development

(2019) Rajendra S. Apte et al.   CELL

Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues

(2019) Lucianna Rabelo Pessoa de Siqueira et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New designs for phototherapeutic transition metal complexes

(2019) Peter J. Sadler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition

(2019) Yujia Yuan et al.   CLINICAL SCIENCE

Novel Brain-Tumor-Inhibiting Copper(II) Compound Based on a Human Serum Albumin (HSA)-Cell Penetrating Peptide Conjugate

(2019) Zhenlei Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

ROS-Inducing Micelles Sensitize Tumor-Associated Macrophages to TLR3 Stimulation for Potent Immunotherapy

(2018) Lanlan Liu et al.   BIOMACROMOLECULES

Impact of tumor microenvironment composition on therapeutic responses and clinical outcomes in cancer

(2018) Fern Anari et al.   Future Oncology

Developing an Anticancer Copper(II) Multitarget Pro-Drug Based on the His146 Residue in the IB Subdomain of Modified Human Serum Albumin

(2018) Jun Wang et al.   MOLECULAR PHARMACEUTICS

Metal Drugs and the Anticancer Immune Response

(2018) Bernhard Englinger et al.   CHEMICAL REVIEWS

Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives

(2017) Tatjana Lazarević et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design of an Anticancer Copper(II) Prodrug Based on the Lys199 Residue of the Active Targeting Human Serum Albumin Nanoparticle Carrier

(2017) Yi Gou et al.   MOLECULAR PHARMACEUTICS

Simple bioconjugate chemistry serves great clinical advances: albumin as a versatile platform for diagnosis and precision therapy

(2016) Zhibo Liu et al.   CHEMICAL SOCIETY REVIEWS

Structure–Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance

(2016) Alexandra E. Stacy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain

(2016) Jinxu Qi et al.   JOURNAL OF MEDICINAL CHEMISTRY

X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism

(2016) Aleksandar Bijelic et al.   JOURNAL OF MEDICINAL CHEMISTRY

Developing an Anticancer Copper(II) Pro-Drug Based on the His242 Residue of the Human Serum Albumin Carrier IIA Subdomain

(2016) Jinxu Qi et al.   MOLECULAR PHARMACEUTICS

Targeting the DNA Damage Response in Cancer

(2015) Mark J. O’Connor   MOLECULAR CELL

Anti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model

(2015) Sandra Durante et al.   Oncotarget

Anti-cancer palladium complexes: a focus on PdX2L2, palladacycles and related complexes

(2014) Anant R. Kapdi et al.   CHEMICAL SOCIETY REVIEWS

DNA Binding Mode of Transition Metal Complexes, A Relationship to Tumor Cell Toxicity

(2014) M. Ashfaq et al.   CURRENT MEDICINAL CHEMISTRY

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

(2014) Yao-Rong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting the Tumor Microenvironment: From Understanding Pathways to Effective Clinical Trials

(2013) H. Fang et al.   CANCER RESEARCH

Novel Chelators for Cancer Treatment: Where Are We Now?

(2012) Angelica M. Merlot et al.   ANTIOXIDANTS & REDOX SIGNALING

Interactive Associations of Drug–Drug and Drug–Drug–Drug with IIA Subdomain of Human Serum Albumin

(2012) Feng Yang et al.   MOLECULAR PHARMACEUTICS

Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy

(2011) Y Yu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Copper complexes of bis(thiosemicarbazones): from chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals

(2011) Brett M. Paterson et al.   CHEMICAL SOCIETY REVIEWS

Human serum albumin: From bench to bedside

(2011) Gabriella Fanali et al.   MOLECULAR ASPECTS OF MEDICINE

Development of an LC–MS/MS method for analysis of interconvertible Z/E isomers of the novel anticancer agent, Bp4eT

(2010) Ján Stariat et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles

(2008) Felix Kratz   JOURNAL OF CONTROLLED RELEASE