Precise and systematic end group chemistry modifications on PAMAM and poly(l-lysine) dendrimers to improve cytosolic delivery of mRNA
出版年份 2023 全文链接
标题
Precise and systematic end group chemistry modifications on PAMAM and poly(l-lysine) dendrimers to improve cytosolic delivery of mRNA
作者
关键词
-
出版物
JOURNAL OF CONTROLLED RELEASE
Volume 356, Issue -, Pages 580-594
出版商
Elsevier BV
发表日期
2023-03-18
DOI
10.1016/j.jconrel.2023.03.011
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Drug delivery systems for RNA therapeutics
- (2022) Kalina Paunovska et al. NATURE REVIEWS GENETICS
- A high-throughput Galectin-9 imaging assay for quantifying nanoparticle uptake, endosomal escape and functional RNA delivery
- (2021) Michael J. Munson et al. Communications Biology
- Lipid-Based Nanoparticles in the Clinic and Clinical Trials: From Cancer Nanomedicine to COVID-19 Vaccines
- (2021) Thai Thanh Hoang Thi et al. Vaccines
- Synthetic modified messenger RNA for therapeutic applications
- (2021) Minsong Gao et al. Acta Biomaterialia
- A novel mechanism for the loss of mRNA activity in lipid nanoparticle delivery systems
- (2021) Meredith Packer et al. Nature Communications
- Lipodendriplexes mediated enhanced gene delivery: a cellular to pre-clinical investigation
- (2020) Imran Tariq et al. Scientific Reports
- Brain gene delivery using histidine and arginine-modified dendrimers for ischemic stroke therapy
- (2020) Youngki Lee et al. JOURNAL OF CONTROLLED RELEASE
- DendriPeps: Expanding Dendrimer Functionality by Hybridizing Poly(amidoamine) (PAMAM) Scaffolds with Peptide Segments
- (2019) Ryan J. Smith et al. MACROMOLECULAR RAPID COMMUNICATIONS
- A “top-down” approach to actuate poly(amine- co -ester) terpolymers for potent and safe mRNA delivery
- (2018) Yuhang Jiang et al. BIOMATERIALS
- Poly (amidoamine) (PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy
- (2018) Jun Li et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates
- (2018) Staci Sabnis et al. MOLECULAR THERAPY
- Molecular Strings Significantly Improved the Gene Transfection Efficiency of Polycations
- (2018) Huapan Fang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The great escape: how cationic polyplexes overcome the endosomal barrier
- (2018) Tanja Bus et al. Journal of Materials Chemistry B
- Highly Efficient In Vivo Targeting of the Pulmonary Endothelium Using Novel Modifications of Polyethylenimine: An Importance of Charge
- (2018) Andrew W. Dunn et al. Advanced Healthcare Materials
- Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals
- (2017) Colin J. McKinlay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model
- (2017) Jasdave S. Chahal et al. Scientific Reports
- Bench-to-bedside translation of dendrimers: Reality or utopia? A concise analysis
- (2017) Serge Mignani et al. ADVANCED DRUG DELIVERY REVIEWS
- A Single Methylene Group in Oligoalkylamine-Based Cationic Polymers and Lipids Promotes Enhanced mRNA Delivery
- (2016) Anita Jarzębińska et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cationic Polymer Intercalation into the Lipid Membrane Enables Intact Polyplex DNA Escape from Endosomes for Gene Delivery
- (2016) Sriram Vaidyanathan et al. MOLECULAR PHARMACEUTICS
- Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, andToxoplasma gondiichallenges with a single dose
- (2016) Jasdave S. Chahal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich’s ataxia
- (2016) Joseph F. Nabhan et al. Scientific Reports
- Surface-Engineered Dendrimers in Gene Delivery
- (2015) Jiepin Yang et al. CHEMICAL REVIEWS
- Polyamidoamine (PAMAM) dendrimers modified with short oligopeptides for early endosomal escape and enhanced gene delivery
- (2015) Le Thi Thuy et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes
- (2015) Norbert Pardi et al. JOURNAL OF CONTROLLED RELEASE
- Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
- (2015) Kevin J. Kauffman et al. NANO LETTERS
- The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration
- (2015) Yong-Bo Hu et al. Translational Neurodegeneration
- Surface-Engineered Dendrimers with a Diaminododecane Core Achieve Efficient Gene Transfection and Low Cytotoxicity
- (2014) Hong Chang et al. BIOCONJUGATE CHEMISTRY
- Arginine-Terminated Generation 4 PAMAM Dendrimer as an Effective Nanovector for Functional siRNA Delivery in Vitro and in Vivo
- (2014) Cheng Liu et al. BIOCONJUGATE CHEMISTRY
- Synergistic effect of amino acids modified on dendrimer surface in gene delivery
- (2014) Fei Wang et al. BIOMATERIALS
- Endosomal Escape: A Bottleneck in Intracellular Delivery
- (2014) Harshad K. Shete et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Modulated Protonation of Side Chain Aminoethylene Repeats in N-Substituted Polyaspartamides Promotes mRNA Transfection
- (2014) Hirokuni Uchida et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Basic amino acid-conjugated polyamidoamine dendrimers with enhanced gene transfection efficiency
- (2014) Jung Hyun Park et al. MACROMOLECULAR RESEARCH
- mRNA-based therapeutics — developing a new class of drugs
- (2014) Ugur Sahin et al. NATURE REVIEWS DRUG DISCOVERY
- A fluorinated dendrimer achieves excellent gene transfection efficacy at extremely low nitrogen to phosphorus ratios
- (2014) Mingming Wang et al. Nature Communications
- A review of the current status of siRNA nanomedicines in the treatment of cancer
- (2013) Pauline Resnier et al. BIOMATERIALS
- Poly(amidoamine) dendrimer complexes as a platform for gene delivery
- (2013) Dzmitry Shcharbin et al. Expert Opinion on Drug Delivery
- The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
- (2012) Eleonore Fröhlich International Journal of Nanomedicine
- Effect of unsaturated alkyl chains on transfection activity of poly(amidoamine) dendron-bearing lipids
- (2012) Eiji Yuba et al. JOURNAL OF CONTROLLED RELEASE
- Amino acid-modified bioreducible poly(amidoamine) dendrimers: Synthesis, characterization and In vitro evaluation
- (2012) Gwang Sig Yu et al. MACROMOLECULAR RESEARCH
- Efficient in Vitro siRNA Delivery and Intramuscular Gene Silencing Using PEG-Modified PAMAM Dendrimers
- (2012) Yin Tang et al. MOLECULAR PHARMACEUTICS
- The effect of pH on PAMAM dendrimer–siRNA complexation — Endosomal considerations as determined by molecular dynamics simulation
- (2011) Defang Ouyang et al. BIOPHYSICAL CHEMISTRY
- PEGylated Polyamidoamine Dendrimers with Bis-Aryl Hydrazone Linkages for Enhanced Gene Delivery
- (2010) Quan Yuan et al. BIOMACROMOLECULES
- Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells
- (2010) José L. Santos et al. JOURNAL OF CONTROLLED RELEASE
- In Vitro and In Vivo gene delivery mediated by Lactosylated Dendrimer/α-Cyclodextrin Conjugates (G2) into Hepatocytes
- (2010) Hidetoshi Arima et al. JOURNAL OF CONTROLLED RELEASE
- Endosomal escape pathways for delivery of biologicals
- (2010) Amir K. Varkouhi et al. JOURNAL OF CONTROLLED RELEASE
- Alkyl sulfonyl derivatized PAMAM-G2dendrimers as nonviral gene delivery vectors with improved transfection efficiencies
- (2010) Julia Morales-Sanfrutos et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
- (2008) Katalin Karikó et al. MOLECULAR THERAPY
- Elimination and exchange of trifluoroacetate counter-ion from cationic peptides: a critical evaluation of different approaches
- (2007) Stéphane Roux et al. JOURNAL OF PEPTIDE SCIENCE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started