Cucurbitacin-B inhibits cancer cell migration by targeting mortalin and HDM2: computational and in vitro experimental evidence
出版年份 2023 全文链接
标题
Cucurbitacin-B inhibits cancer cell migration by targeting mortalin and HDM2: computational and in vitro experimental evidence
作者
关键词
-
出版物
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
Volume -, Issue -, Pages 1-10
出版商
Informa UK Limited
发表日期
2023-05-02
DOI
10.1080/07391102.2023.2206914
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Epithelial–Mesenchymal Transition at the Crossroads between Metabolism and Tumor Progression
- (2022) Monica Fedele et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Of the many cellular responses activated by TP53, which ones are critical for tumour suppression?
- (2022) Annabella F. Thomas et al. CELL DEATH AND DIFFERENTIATION
- Wnt signaling in colorectal cancer: pathogenic role and therapeutic target
- (2022) Hui Zhao et al. Molecular Cancer
- Why is Mortalin a Potential Therapeutic Target for Cancer?
- (2022) A-Rum Yoon et al. Frontiers in Cell and Developmental Biology
- A comprehensive study of p53 protein
- (2022) Manisha R. Patil et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- p53: From Fundamental Biology to Clinical Applications in Cancer
- (2022) Maurizio Capuozzo et al. Biology-Basel
- Cucurbitacin II a: A review of phytochemistry and pharmacology
- (2021) Yijia Zeng et al. PHYTOTHERAPY RESEARCH
- Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells
- (2021) Zeenia Kaul et al. Scientific Reports
- Molecular and cellular mechanisms controlling integrin-mediated cell adhesion and tumor progression in ovarian cancer metastasis: a review
- (2021) Dolly Dhaliwal et al. CLINICAL & EXPERIMENTAL METASTASIS
- Dual role of E-cadherin in cancer cells
- (2021) Svetlana N. Rubtsova et al. Tissue Barriers
- Cucurbitacin B controls M2 macrophage polarization to suppresses metastasis via targeting JAK-2/STAT3 signalling pathway in colorectal cancer
- (2021) Haoyue Zhang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Soyasapogenol-A targets CARF and results in suppression of tumor growth and metastasis in p53 compromised cancer cells
- (2020) Amr Omar et al. Scientific Reports
- An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition
- (2020) Kaiyuan Wang et al. BIOMATERIALS
- Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential
- (2019) Sukant Garg et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Modified mixed nanomicelles with collagen peptides enhanced oral absorption of Cucurbitacin B: preparation and evaluation
- (2018) Lan Tang et al. DRUG DELIVERY
- Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity
- (2018) Ya-Ju Sung et al. Cell Death & Disease
- CARF enrichment promotes epithelial–mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target
- (2018) Rajkumar S. Kalra et al. Oncogenesis
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis
- (2016) Samriddhi Shukla et al. Scientific Reports
- OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins
- (2015) Edward Harder et al. Journal of Chemical Theory and Computation
- Identification and Functional Characterization of Nuclear Mortalin in Human Carcinogenesis
- (2014) Jihoon Ryu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH-SY5Y human neuroblastoma cells
- (2014) QIAN ZHENG et al. Molecular Medicine Reports
- Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
- (2013) G. Madhavi Sastry et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Mortalin–p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy
- (2011) W-J Lu et al. CELL DEATH AND DIFFERENTIATION
- Withanone binds to mortalin and abrogates mortalin–p53 complex: Computational and experimental evidence
- (2011) Abhinav Grover et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Role of p53 Serine 46 in p53 Target Gene Regulation
- (2011) Leonie Smeenk et al. PLoS One
- Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin
- (2010) Wen-Jing Lu et al. INTERNATIONAL JOURNAL OF CANCER
- Roles of E3 ubiquitin ligases in cell adhesion and migration
- (2010) Cai Huang Cell Adhesion & Migration
- Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells
- (2009) N. H. Thoennissen et al. CANCER RESEARCH
- CARF: An emerging regulator of p53 tumor suppressor and senescence pathway
- (2008) Caroline T.Y. Cheung et al. MECHANISMS OF AGEING AND DEVELOPMENT
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