An emerging master inducer and regulator for epithelial-mesenchymal transition and tumor metastasis: extracellular and intracellular ATP and its molecular functions and therapeutic potential
出版年份 2023 全文链接
标题
An emerging master inducer and regulator for epithelial-mesenchymal transition and tumor metastasis: extracellular and intracellular ATP and its molecular functions and therapeutic potential
作者
关键词
-
出版物
Cancer Cell International
Volume 23, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2023-02-07
DOI
10.1186/s12935-023-02859-0
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- From Transcriptomics, Metabolomics to Functional Studies: Extracellular ATP Induces TGF-β-Like Epithelial Mesenchymal Transition in Lung Cancer Cells
- (2022) Maria Evers et al. Frontiers in Oncology
- Cancer Stem Cell Formation Induced and Regulated by Extracellular ATP and Stanniocalcin-1 in Human Lung Cancer Cells and Tumors
- (2022) Jingwen Song et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting metastatic cancer
- (2021) Karuna Ganesh et al. NATURE MEDICINE
- Extracellular ATP Mediates Cancer Cell Migration and Invasion Through Increased Expression of Cyclooxygenase 2
- (2021) Shilpa Sharma et al. Frontiers in Pharmacology
- The Dual Role of Macropinocytosis in Cancers: Promoting Growth and Inducing Methuosis to Participate in Anticancer Therapies as Targets
- (2021) Shaojuan Song et al. Frontiers in Oncology
- Distinct nutrient use in tumors
- (2021) John F. Foley Science Signaling
- Molecular basis of V-ATPase inhibition by bafilomycin A1
- (2021) Rong Wang et al. Nature Communications
- Liposomes and Extracellular Vesicles as Drug Delivery Systems: A Comparison of Composition, Pharmacokinetics, and Functionalization
- (2021) Luke Koog et al. Advanced Healthcare Materials
- Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells
- (2021) Laetitia Seguin et al. Communications Biology
- Macropinocytosis confers resistance to therapies targeting cancer anabolism
- (2020) Vaishali Jayashankar et al. Nature Communications
- Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition
- (2020) Evdokia Michalopoulou et al. Cell Reports
- Tumor microenvironment complexity and therapeutic implications at a glance
- (2020) Roghayyeh Baghban et al. Cell Communication and Signaling
- Extracellular ATP promotes breast cancer invasion and chemoresistance via SOX9 signaling
- (2020) Hui Yang et al. ONCOGENE
- TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancer
- (2020) Bit Na Kim et al. Scientific Reports
- GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery
- (2020) Lauren V. Albrecht et al. Cell Reports
- P2X7 in Cancer: From Molecular Mechanisms to Therapeutics
- (2020) Romain Lara et al. Frontiers in Pharmacology
- The tumor microenvironment
- (2020) Nicole M. Anderson et al. CURRENT BIOLOGY
- Characterisation of P2Y 2 receptors in human vascular endothelial cells using AR‐C118925XX, a competitive and selective P2Y 2 antagonist
- (2019) Markie O. Muoboghare et al. BRITISH JOURNAL OF PHARMACOLOGY
- Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis
- (2019) Wei Lu et al. DEVELOPMENTAL CELL
- The m6A-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca2+ influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway
- (2019) Dongkui Gong et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Extracellular and macropinocytosis internalized ATP work together to induce epithelial–mesenchymal transition and other early metastatic activities in lung cancer
- (2019) Yanyang Cao et al. Cancer Cell International
- The Acidic Tumor Microenvironment as a Driver of Cancer
- (2019) Ebbe Boedtkjer et al. Annual Review of Physiology
- Flavonoids as anticancer therapies: A systematic review of clinical trials
- (2019) Ângela Bisol et al. PHYTOTHERAPY RESEARCH
- Effects of gefitinib treatment on cellular uptake of extracellular vesicles in EGFR-mutant non-small cell lung cancer cells
- (2019) Tomoya Takenaka et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Identification of novel macropinocytosis inhibitors using a rational screen of FDA-approved drugs
- (2018) Hui-Ping Lin et al. BRITISH JOURNAL OF PHARMACOLOGY
- Stanniocalcin-1 augments stem-like traits of glioblastoma cells through binding and activating NOTCH1
- (2018) Yong Li et al. CANCER LETTERS
- The Canonical Wnt Pathway Drives Macropinocytosis in Cancer
- (2018) Gil Redelman-Sidi et al. CANCER RESEARCH
- Recent Advances in pH-Sensitive Polymeric Nanoparticles for Smart Drug Delivery in Cancer Therapy
- (2018) Eun-Kyung Lim et al. CURRENT DRUG TARGETS
- PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells
- (2018) Seong M. Kim et al. Cancer Discovery
- The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?
- (2018) Luiz E. B. Savio et al. Frontiers in Pharmacology
- Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations
- (2018) Judith A. Seidel et al. Frontiers in Oncology
- Abstract 2019: Extracellular ATP induces EMT and metastatic activities in non-small cell lung cancer cells
- (2018) Yanyang Cao et al. CANCER RESEARCH
- ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival
- (2018) SM Gilbert et al. ONCOGENE
- Role of platelets and platelet receptors in cancer metastasis
- (2018) Martin Schlesinger Journal of Hematology & Oncology
- Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability
- (2018) Toni Celià-Terrassa et al. Nature Communications
- The P2X7 Receptor in Infection and Inflammation
- (2017) Francesco Di Virgilio et al. IMMUNITY
- The P2X7 receptor antagonist, oxidized adenosine triphosphate, ameliorates renal ischemia-reperfusion injury by expansion of regulatory T cells
- (2017) Tai Yeon Koo et al. KIDNEY INTERNATIONAL
- EMT and MET: necessary or permissive for metastasis?
- (2017) Mohit Kumar Jolly et al. Molecular Oncology
- Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response
- (2017) Junbin Han et al. NUCLEAR MEDICINE COMMUNICATIONS
- Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers
- (2017) Laetitia Seguin et al. Cancer Discovery
- A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles
- (2017) Vito W. Rebecca et al. Cancer Discovery
- Carcinoma-specific expression of P2Y11 receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells
- (2017) Madiha Khalid et al. Oncotarget
- Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1
- (2017) Hirotada Tajiri et al. Cell Reports
- Role of tumor microenvironment in tumorigenesis
- (2017) Maonan Wang et al. Journal of Cancer
- Nanobody-Based Delivery Systems for Diagnosis and Targeted Tumor Therapy
- (2017) Yaozhong Hu et al. Frontiers in Immunology
- Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer
- (2017) Maria Victoria Recouvreux et al. Frontiers in Endocrinology
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- A multicenter phase II study of sepantronium bromide (YM155) plus rituximab in patients with relapsed aggressive B-cell Non-Hodgkin lymphoma
- (2016) Kyriakos P. Papadopoulos et al. LEUKEMIA & LYMPHOMA
- Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms
- (2016) Y. Qian et al. MOLECULAR CANCER RESEARCH
- Role of the tumor microenvironment in tumor progression and the clinical applications (Review)
- (2016) YAO YUAN et al. ONCOLOGY REPORTS
- Synthesis, characterization, and in vitro evaluation of the selective P2Y2 receptor antagonist AR-C118925
- (2016) Muhammad Rafehi et al. Purinergic Signalling
- A critical look at the function of the P2Y11 receptor
- (2016) Karin Dreisig et al. Purinergic Signalling
- P2X7 targeting inhibits growth of human mesothelioma
- (2016) Francesca Amoroso et al. Oncotarget
- Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human
- (2015) Emily A. Caseley et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis
- (2015) M. Ruscetti et al. CANCER RESEARCH
- Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
- (2015) M. J. Schliekelman et al. CANCER RESEARCH
- Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells
- (2015) Francesca Andriani et al. Molecular Oncology
- Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival
- (2015) Paul W. Furlow et al. NATURE CELL BIOLOGY
- P2Y2 nucleotide receptor-mediated extracellular signal-regulated kinases and protein kinase C activation induces the invasion of highly metastatic breast cancer cells
- (2015) SO YOUNG EUN et al. ONCOLOGY REPORTS
- P2X7 receptor stimulates breast cancer cell invasion and migration via the AKT pathway
- (2015) JIYI XIA et al. ONCOLOGY REPORTS
- ATP release through pannexon channels
- (2015) Gerhard Dahl PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival
- (2015) Anne Grosse-Wilde et al. PLoS One
- The oncogenetic role of stanniocalcin 1 in lung adenocarcinoma: a promising serum candidate biomarker for tracking lung adenocarcinoma progression
- (2015) Yu-Zhen Du et al. TUMOR BIOLOGY
- P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway
- (2015) Wei-Hua Li et al. PLoS One
- Extracellular ATP is internalized by macropinocytosis and induces intracellular ATP increase and drug resistance in cancer cells
- (2014) Yanrong Qian et al. CANCER LETTERS
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis
- (2014) Marta R.S. Carmo et al. NEUROPHARMACOLOGY
- P2X7 Mediates ATP-Driven Invasiveness in Prostate Cancer Cells
- (2014) Ying Qiu et al. PLoS One
- P2Y2 receptor promotes cell invasion and metastasis in prostate cancer cells
- (2013) W-H Li et al. BRITISH JOURNAL OF CANCER
- Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567
- (2013) Anindya Bhattacharya et al. BRITISH JOURNAL OF PHARMACOLOGY
- Platelet-Derived Nucleotides Promote Tumor-Cell Transendothelial Migration and Metastasis via P2Y2 Receptor
- (2013) Dagmar Schumacher et al. CANCER CELL
- mTOR kinase inhibitors as potential cancer therapeutic drugs
- (2013) Shi-Yong Sun CANCER LETTERS
- Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors
- (2013) Bilel Jelassi et al. CARCINOGENESIS
- Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance
- (2013) Agnieszka Kaczmarek et al. IMMUNITY
- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Autocrine Regulation of Macrophage Activation via Exocytosis of ATP and Activation of P2Y11 Receptor
- (2013) Hayato Sakaki et al. PLoS One
- New intriguing roles of ATP and its receptors in promoting tumor metastasis
- (2013) Elena Adinolfi Purinergic Signalling
- Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
- (2013) M. A. Nieto SCIENCE
- CD39 and CD73 in immunity and inflammation
- (2013) Luca Antonioli et al. TRENDS IN MOLECULAR MEDICINE
- An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
- (2013) R Y-J Huang et al. Cell Death & Disease
- Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
- (2012) Oscar H. Ocaña et al. CANCER CELL
- Mechanisms of ATP release and signalling in the blood vessel wall
- (2012) A. W. Lohman et al. CARDIOVASCULAR RESEARCH
- P2X7 receptor regulation of non-classical secretion from immune effector cells
- (2012) George R. Dubyak CELLULAR MICROBIOLOGY
- Pannexin 1, an ATP Release Channel, Is Activated by Caspase Cleavage of Its Pore-associated C-terminal Autoinhibitory Region
- (2012) Joanna K. Sandilos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Contribution of intracellular ATP to cisplatin resistance of tumor cells
- (2012) Verena Schneider et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Autocrine regulation of TGF- 1-induced cell migration by exocytosis of ATP and activation of P2 receptors in human lung cancer cells
- (2012) E. Takai et al. JOURNAL OF CELL SCIENCE
- Efficacy and Safety of CE-224,535, an Antagonist of P2X7 Receptor, in Treatment of Patients with Rheumatoid Arthritis Inadequately Controlled by Methotrexate
- (2012) T. C. STOCK et al. JOURNAL OF RHEUMATOLOGY
- The Initial Hours of Metastasis: The Importance of Cooperative Host-Tumor Cell Interactions during Hematogenous Dissemination
- (2012) M. Labelle et al. Cancer Discovery
- Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells
- (2011) Y. Zhou et al. CANCER RESEARCH
- Anoikis: an emerging hallmark in health and diseases
- (2011) ML Taddei et al. JOURNAL OF PATHOLOGY
- P2X7 receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness
- (2011) B Jelassi et al. ONCOGENE
- A Perspective on Cancer Cell Metastasis
- (2011) C. L. Chaffer et al. SCIENCE
- Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes
- (2010) Meera Sridharan et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Purinergic Receptor Inhibition Prevents the Development of Smoke-Induced Lung Injury and Emphysema
- (2010) S. Cicko et al. JOURNAL OF IMMUNOLOGY
- Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R
- (2010) Konrad Wilhelm et al. NATURE MEDICINE
- A Clathrin Independent Macropinocytosis-Like Entry Mechanism Used by Bluetongue Virus-1 during Infection of BHK Cells
- (2010) Sarah Gold et al. PLoS One
- Purinergic mechanisms in breast cancer support intravasation, extravasation and angiogenesis
- (2009) Iain L.O. Buxton et al. CANCER LETTERS
- Phosphoinositide 3-kinase inhibitor (wortmannin) inhibits pancreatic cancer cell motility and migration induced by hyaluronanin vitroand peritoneal metastasisin vivo
- (2009) Futoshi Teranishi et al. CANCER SCIENCE
- TGF-β-induced epithelial to mesenchymal transition
- (2009) Jian Xu et al. CELL RESEARCH
- Effects of Extracellular ATP on Bovine Lung Endothelial and Epithelial Cell Monolayer Morphologies, Apoptoses, and Permeabilities
- (2008) D. McClenahan et al. Clinical and Vaccine Immunology
- Inhibition of “self” engulfment through deactivation of myosin-II at the phagocytic synapse between human cells
- (2008) Richard K. Tsai et al. JOURNAL OF CELL BIOLOGY
- Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase
- (2008) Patrizia Pellegatti et al. PLoS One
- Development of selective agonists and antagonists of P2Y receptors
- (2008) Kenneth A. Jacobson et al. Purinergic Signalling
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started