Extracellular ATP promotes breast cancer invasion and chemoresistance via SOX9 signaling

aarF domain containing kinase 5 gene promotes invasion and migration of lung cancer cells through ADCK5-SOX9-PTTG1 pathway

(2020) Minglian Qiu et al.   EXPERIMENTAL CELL RESEARCH

Extracellular ATP promotes breast cancer invasion and epithelial‐mesenchymal transition via hypoxia‐inducible factor 2α signaling

(2019) Hui Yang et al.   CANCER SCIENCE

Extracellular ATP drives breast cancer cell migration and metastasis via S100A4 production by cancer cells and fibroblasts

(2018) Ying Liu et al.   CANCER LETTERS

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets

(2018) Ádám Nagy et al.   Scientific Reports

ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival

(2018) SM Gilbert et al.   ONCOGENE

The dose-dependent effect of SOX9 and its incidence in colorectal cancer

(2017) Corinne Prévostel et al.   EUROPEAN JOURNAL OF CANCER

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

(2017) Christopher Abbosh et al.   NATURE

Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein

(2017) Brandy Verhalen et al.   NATURE

P2Y2 receptor promotes the migration and invasion of breast cancer cells via EMT-related genes Snail and E-cadherin

(2017) Ying Qiu et al.   ONCOLOGY REPORTS

ATP as a biological hydrotrope

(2017) Avinash Patel et al.   SCIENCE

Extracellular ATP, as an energy and phosphorylating molecule, induces different types of drug resistances in cancer cells through ATP internalization and intracellular ATP level increase

(2017) Xuan Wang et al.   Oncotarget

FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis

(2016) Lin Shan et al.   CANCER CELL

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer

(2016) Hanlin Zeng et al.   CANCER CELL

SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression

(2016) Juliana Carvalho Santos et al.   CANCER RESEARCH

P2 receptors in cancer progression and metastatic spreading

(2016) Francesco Di Virgilio et al.   CURRENT OPINION IN PHARMACOLOGY

Extracellular purines, purinergic receptors and tumor growth

(2016) F Di Virgilio et al.   ONCOGENE

Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling

(2016) Carmen Oi-Ning Leung et al.   Oncotarget

The Osteogenic Niche Promotes Early-Stage Bone Colonization of Disseminated Breast Cancer Cells

(2015) Hai Wang et al.   CANCER CELL

Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion

(2015) Jean-Christophe Larsimont et al.   Cell Stem Cell

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Necrosis: Linking the Inflammasome to Inflammation

(2015) Lorenzo Galluzzi et al.   Cell Reports

Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney

(2015) Sanjeev Kumar et al.   Cell Reports

P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway

(2015) Wei-Hua Li et al.   PLoS One

The Regulation of Sox2 and Sox9 Stimulated by ATP in Spinal Cord Astrocytes

(2014) Maosheng Xia et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

P2X7 Mediates ATP-Driven Invasiveness in Prostate Cancer Cells

(2014) Ying Qiu et al.   PLoS One

Patient-derived models of acquired resistance can identify effective drug combinations for cancer

(2014) Adam S. Crystal et al.   SCIENCE

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

P2Y2 receptor promotes cell invasion and metastasis in prostate cancer cells

(2013) W-H Li et al.   BRITISH JOURNAL OF CANCER

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

(2013) Changmeng Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

Purines, Purinergic Receptors, and Cancer

(2012) F. Di Virgilio   CANCER RESEARCH

P2X7 receptor antagonism in the treatment of cancers

(2011) Sébastien Roger et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancer

(2010) Tracy Putoczki et al.   JOURNAL OF LEUKOCYTE BIOLOGY

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

SOX9 Is Expressed in Human Fetal Prostate Epithelium and Enhances Prostate Cancer Invasion

(2008) H. Wang et al.   CANCER RESEARCH

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium

(2008) H Zalzali et al.   ONCOGENE