标题
Macropinocytosis confers resistance to therapies targeting cancer anabolism
作者
关键词
-
出版物
Nature Communications
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-02-28
DOI
10.1038/s41467-020-14928-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer
- (2019) Cindy Hodakoski et al. Cancers
- Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer
- (2019) Matthew J. Watt et al. Science Translational Medicine
- Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
- (2019) Christopher J. Halbrook et al. Cell Metabolism
- Role of tumor and host autophagy in cancer metabolism
- (2019) Laura Poillet-Perez et al. GENES & DEVELOPMENT
- EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis
- (2019) Szu-Wei Lee et al. DEVELOPMENTAL CELL
- PI3Kβ is selectively required for growth factor-stimulated macropinocytosis
- (2019) Gilbert Salloum et al. JOURNAL OF CELL SCIENCE
- The Canonical Wnt Pathway Drives Macropinocytosis in Cancer
- (2018) Gil Redelman-Sidi et al. CANCER RESEARCH
- AMP kinase promotes glioblastoma bioenergetics and tumour growth
- (2018) Rishi Raj Chhipa et al. NATURE CELL BIOLOGY
- PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells
- (2018) Seong M. Kim et al. Cancer Discovery
- Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
- (2018) Raquel Buj et al. Frontiers in Endocrinology
- PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer.
- (2018) Vito W Rebecca et al. Cancer Discovery
- mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein
- (2017) Michel Nofal et al. MOLECULAR CELL
- Protein O-GlcNAcylation: emerging mechanisms and functions
- (2017) Xiaoyong Yang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Critical role for PI3-kinase in regulating the use of proteins as an amino acid source
- (2017) Wilhelm Palm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer
- (2017) Kristin K. Brown et al. Cancer Discovery
- One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy
- (2017) Oleg Shuvalov et al. Oncotarget
- Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1
- (2017) Hirotada Tajiri et al. Cell Reports
- Relationship between necrotic patterns in glioblastoma and patient survival: fractal dimension and lacunarity analyses using magnetic resonance imaging
- (2017) Shuai Liu et al. Scientific Reports
- Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
- (2016) Shawn M. Davidson et al. Cell Metabolism
- Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
- (2016) Jessie Yanxiang Guo et al. GENES & DEVELOPMENT
- Landscape of somatic mutations in 560 breast cancer whole-genome sequences
- (2016) Serena Nik-Zainal et al. NATURE
- Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
- (2016) Shawn M Davidson et al. NATURE MEDICINE
- p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway
- (2016) Derek A. Franklin et al. Scientific Reports
- Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma
- (2015) Brian A. Boone et al. ANNALS OF SURGICAL ONCOLOGY
- Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
- (2015) J. J. Kamphorst et al. CANCER RESEARCH
- The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1
- (2015) Wilhelm Palm et al. CELL
- Association of PIK3CA Mutation Status before and after Neoadjuvant Chemotherapy with Response to Chemotherapy in Women with Breast Cancer
- (2015) H. Yuan et al. CLINICAL CANCER RESEARCH
- Molecular Pathways: Fatty Acid Synthase
- (2015) S. F. Jones et al. CLINICAL CANCER RESEARCH
- How cell death shapes cancer
- (2015) V Labi et al. Cell Death & Disease
- A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site
- (2014) Mary Ann Hardwicke et al. Nature Chemical Biology
- Specific and quantitative labeling of biomolecules using click chemistry
- (2014) Kenichi Horisawa Frontiers in Physiology
- Physiological role of the interaction between CARMIL1 and capping protein
- (2013) Marc Edwards et al. MOLECULAR BIOLOGY OF THE CELL
- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
- Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells
- (2012) Toran Sanli et al. RADIOTHERAPY AND ONCOLOGY
- Prognostic value of tumour necrosis and host inflammatory responses in colorectal cancer
- (2011) C. H. Richards et al. BRITISH JOURNAL OF SURGERY
- The prognostic value of histological tumor necrosis in solid organ malignant disease: a systematic review
- (2011) Colin H Richards et al. Future Oncology
- Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: An orally active anti-cancer drug waiting for its call-of-duty?
- (2011) Hayden Matthews et al. INTERNATIONAL JOURNAL OF CANCER
- Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy
- (2011) Qian Huang et al. NATURE MEDICINE
- The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
- (2010) K. E. Wellen et al. GENES & DEVELOPMENT
- Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells
- (2010) Toran Sanli et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling
- (2010) Mirkka Koivusalo et al. JOURNAL OF CELL BIOLOGY
- O-GlcNAc signaling: a metabolic link between diabetes and cancer?
- (2010) C. Slawson et al. TRENDS IN BIOCHEMICAL SCIENCES
- Prognostic and predictive impact of central necrosis and fibrosis in early breast cancer: Results from two International Breast Cancer Study Group randomized trials of chemoendocrine adjuvant therapy
- (2009) Eugenio Maiorano et al. BREAST CANCER RESEARCH AND TREATMENT
- Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer
- (2009) William B. Parker CHEMICAL REVIEWS
- Distinct Roles for CARMIL Isoforms in Cell Migration
- (2009) Yun Liang et al. MOLECULAR BIOLOGY OF THE CELL
- Knockin of mutant PIK3CA activates multiple oncogenic pathways
- (2009) John P. Gustin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PIK3CA Mutations and BRCA1 Expression in Breast Cancer: Potential Biomarkers for Chemoresistance
- (2008) Mariacarmela Santarpia et al. CANCER INVESTIGATION
- Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors
- (2008) L S Steelman et al. ONCOGENE
- A chemical method for fast and sensitive detection of DNA synthesis in vivo
- (2008) A. Salic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started