Tetramethylpyrazine-Rhein Derivative inhibits the migration of canine inflammatory mammary carcinoma cells by mitochondrial damage-mediated apoptosis and cadherins downregulation

Tetramethylpyrazine: A review on its mechanisms and functions

(2022) Jianguo Lin et al.   BIOMEDICINE & PHARMACOTHERAPY

Rhein activated Fas-induced apoptosis pathway causing cardiotoxicity in vitro and in vivo

(2022) Gang min Li et al.   TOXICOLOGY LETTERS

Establishment of stable expression of firefly luciferase and EGFP in a canine inflammatory mammary carcinoma cell line and tumor-bearing model in nude mice

(2022) Fangying Zhao et al.   Frontiers in Veterinary Science

Cell adhesion molecules E-cadherin and CADM1 are differently expressed in canine inflammatory mammary cancer

(2022) A. Alonso-Diez et al.   RESEARCH IN VETERINARY SCIENCE

The Analysis of E-Cadherin, N-Cadherin, Vimentin, HER-2, CEA, CA15-3 and SF Expression in the Diagnosis of Canine Mammary Tumors

(2022) Chao Yu et al.   Animals

Cancer statistics for the year 2020: An overview

(2021) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

TAD1822-7 induces ROS-mediated apoptosis of HER2 positive breast cancer by decreasing E-cadherin in an EphB4 dependent manner

(2021) Man Zhu et al.   LIFE SCIENCES

Tetramethylpyrazine: A Review of Its Antitumor Potential and Mechanisms

(2021) Shaojie Yang et al.   Frontiers in Pharmacology

Therapeutic Emergence of Rhein as a Potential Anticancer Drug: A Review of Its Molecular Targets and Anticancer Properties

(2020) Sahu Henamayee et al.   MOLECULES

Prognostic significance of immunohistochemical markers and histological classification in malignant canine mammary tumours

(2020) Nieves Pastor et al.   Veterinary and Comparative Oncology

Rhein Derivative 4F Inhibits the Malignant Phenotype of Breast Cancer by Downregulating Rac1 Protein

(2020) Xinxiao Li et al.   Frontiers in Pharmacology

Role of Cadherins in Cancer—A Review

(2020) Ilona Kaszak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rhein shows potent efficacy against non-small-cell lung cancer through inhibiting the STAT3 pathway

(2019) Lehe Yang et al.   Cancer Management and Research

An autophagy-dependent cell death of MDA-MB-231 cells triggered by a novel Rhein derivative 4F

(2019) Yunfeng Liu et al.   ANTI-CANCER DRUGS

P120 and E-cadherin: double-edged swords in tumor metastasis

(2019) Jan-Hendrik Venhuizen et al.   SEMINARS IN CANCER BIOLOGY

E-cadherin is required for metastasis in multiple models of breast cancer

(2019) Veena Padmanaban et al.   NATURE

Rhein Augments Antiproliferative Effects of Atezolizumab Based on Breast Cancer (4T1) Regression

(2019) Zhanyun Shen et al.   PLANTA MEDICA

Aberrant N-cadherin expression in cancer

(2019) Zhan-Qi Cao et al.   BIOMEDICINE & PHARMACOTHERAPY

Rhein Induces Cell Death in HepaRG Cells through Cell Cycle Arrest and Apoptotic Pathway

(2018) Longtai You et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inflammatory Breast Cancer

(2018) Arjun Menta et al.   SURGICAL CLINICS OF NORTH AMERICA

Comparative aspects of canine and human inflammatory breast cancer

(2017) Teresa P. Raposo et al.   SEMINARS IN ONCOLOGY

The UCP2-related mitochondrial pathway participates in rhein-induced apoptosis in HK-2 cells

(2017) Yong Mao et al.   Toxicology Research

Tetramethylpyrazine inhibits tumor growth of lung cancer through disrupting angiogenesis via BMP/Smad/Id-1 signaling

(2016) YOUCHAO JIA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Incidence of mammary tumors in the canine population living in the Veneto region (Northeastern Italy): Risk factors and similarities to human breast cancer

(2016) Marta Vascellari et al.   PREVENTIVE VETERINARY MEDICINE

Ligustrazine induces apoptosis of breast cancer cells in vitro and in vivo

(2015) Guo-Qin Jiang et al.   Journal of Cancer Research and Therapeutics

Hispolon inhibits breast cancer cell migration by reversal of epithelial-to-mesenchymal transition via suppressing the ROS/ERK/Slug/E-cadherin pathway

(2015) ZHAO ZHAO et al.   ONCOLOGY REPORTS

Synthesis and Antitumor Evaluation of One Novel Tetramethylpyrazine-Rhein Derivative

(2014)   ASIAN JOURNAL OF CHEMISTRY

Rhein inhibits angiogenesis and the viability of hormone-dependent and -independent cancer cells under normoxic or hypoxic conditions in vitro

(2011) Vivian E. Fernand et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anti-proliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells

(2009) Gabriella Aviello et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rhein lysinate suppresses the growth of breast cancer cells and potentiates the inhibitory effect of Taxol in athymic mice

(2008) Ya-Jun Lin et al.   ANTI-CANCER DRUGS

Filopodia: molecular architecture and cellular functions

(2008) Pieta K. Mattila et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY