Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway
出版年份 2023 全文链接
标题
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway
作者
关键词
-
出版物
BIOMEDICINE & PHARMACOTHERAPY
Volume 160, Issue -, Pages 114319
出版商
Elsevier BV
发表日期
2023-01-30
DOI
10.1016/j.biopha.2023.114319
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- E3 ubiquitin ligase Grail promotes hepatic steatosis through Sirt1 inhibition
- (2021) Pei-Yao Liu et al. Cell Death & Disease
- Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: Biological activity and structural modification
- (2020) Mingying Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- MAFLD: A consensus-driven proposed nomenclature for metabolic associated fatty liver disease
- (2020) Mohammed Eslam et al. GASTROENTEROLOGY
- Therapeutic landscape for NAFLD in 2020
- (2020) Brent A. Neuschwander-Tetri GASTROENTEROLOGY
- NAFLD 2020: The State of the Disease
- (2020) Thomas G. Cotter et al. GASTROENTEROLOGY
- Epidemiological feature of NAFLD from 1999 to 2018 in China
- (2020) Jianghua Zhou et al. HEPATOLOGY
- 20(S)-Protopanaxadiol Inhibits Titanium Particle-Induced Inflammatory Osteolysis and RANKL-Mediated Osteoclastogenesis via MAPK and NF-κB Signaling Pathways
- (2019) Chenhao Pan et al. Frontiers in Pharmacology
- miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease
- (2019) Jun-Ke Long et al. MOLECULAR MEDICINE
- Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999–2019: a systematic review and meta-analysis
- (2019) Jie Li et al. Lancet Gastroenterology & Hepatology
- Vitexin alleviates non-alcoholic fatty liver disease by activating AMPK in high fat diet fed mice
- (2019) Shrirang Inamdar et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology
- (2019) Mohammed Eslam et al. Nature Reviews Gastroenterology & Hepatology
- Gynostemma Pentaphyllum Extract Ameliorates High-Fat Diet-Induced Obesity in C57BL/6N Mice by Upregulating SIRT1
- (2019) Hyun Sook Lee et al. Nutrients
- LB100 ameliorates nonalcoholic fatty liver disease via the AMPK/Sirt1 pathway
- (2019) Xue-Yang Chen et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Animal models of NAFLD from a hepatologist's point of view
- (2018) Daniel Jahn et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- AMPK-Mediated Regulation of Lipid Metabolism by Phosphorylation
- (2018) Qi Wang et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- AMPK: Sensing Glucose as well as Cellular Energy Status
- (2018) Sheng-Cai Lin et al. Cell Metabolism
- Comparison of Calorie-Restricted Diet and Resveratrol Supplementation on Anthropometric Indices, Metabolic Parameters, and Serum Sirtuin-1 Levels in Patients With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Clinical Trial
- (2018) Somayyeh Asghari et al. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
- Mechanisms of NAFLD development and therapeutic strategies
- (2018) Scott L. Friedman et al. NATURE MEDICINE
- The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice
- (2017) Zhiwen Fan et al. HEPATOLOGY
- AMPK as a Therapeutic Target for Treating Metabolic Diseases
- (2017) Emily A. Day et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Ameliorative effects of Compound K and ginsenoside Rh1 on non-alcoholic fatty liver disease in rats
- (2017) Xu-Jia Chen et al. Scientific Reports
- 20 S -Protopanaxadiol, an aglycosylated ginsenoside metabolite, induces hepatic stellate cell apoptosis through liver kinase B1–AMP-activated protein kinase activation
- (2017) Sang Mi Park et al. Journal of Ginseng Research
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Non-alcoholic fatty liver disease and dyslipidemia: An update
- (2016) Niki Katsiki et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease
- (2016) Vera H. I. Fengler et al. PLoS One
- Discovery, synthesis, and structure–activity relationships of 20(S)-protopanaxadiol (PPD) derivatives as a novel class of AMPKα2β1γ1 activators
- (2014) Junhua Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Antiobesity effect ofGynostemma pentaphyllumextract (actiponin): A randomized, double-blind, placebo-controlled trial
- (2013) Soo-Hyun Park et al. Obesity
- Role of AMP-activated Protein Kinase and Adiponectin during Development of Hepatic Steatosis in High-fat Diet-induced Obesity in Rats
- (2011) S.-K. Ha et al. JOURNAL OF COMPARATIVE PATHOLOGY
- Identification of 20(S)-Protopanaxadiol Metabolites in Human Liver Microsomes and Human Hepatocytes
- (2010) L. Li et al. DRUG METABOLISM AND DISPOSITION
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
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