JNK Activation in Alzheimer’s Disease Is Driven by Amyloid β and Is Associated with Tau Pathology
出版年份 2023 全文链接
标题
JNK Activation in Alzheimer’s Disease Is Driven by Amyloid β and Is Associated with Tau Pathology
作者
关键词
-
出版物
ACS Chemical Neuroscience
Volume -, Issue -, Pages -
出版商
American Chemical Society (ACS)
发表日期
2023-03-29
DOI
10.1021/acschemneuro.3c00093
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Recent advances of small molecule JNK3 inhibitors for Alzheimer’s disease
- (2022) Pengxia Qin et al. BIOORGANIC CHEMISTRY
- Discovery of novel imidazole chemotypes as isoform-selective JNK3 inhibitors for the treatment of Alzheimer's disease
- (2022) Joonhong Jun et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Novel 1,4,5,6-tetrahydrocyclopenta[d]imidazole-5-carboxamide-based JNK3 inhibitors: Design, synthesis, molecular docking, and therapeutic potential in neurodegenerative diseases
- (2022) Joonhong Jun et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- A Perspective on the Development of c-Jun N-terminal Kinase Inhibitors as Therapeutics for Alzheimer’s Disease: Investigating Structure through Docking Studies
- (2021) Hyunwook Cho et al. Biomedicines
- c-Jun N-Terminal Kinase Inhibitors as Potential Leads for New Therapeutics for Alzheimer’s Diseases
- (2020) Stephanie Cristine Hepp Rehfeldt et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Interaction of amyloidogenic proteins in pancreatic β cells from subjects with synucleinopathies
- (2018) Ivan Martinez-Valbuena et al. ACTA NEUROPATHOLOGICA
- Amyloid-β42 Activates the Expression of BACE1 Through the JNK Pathway
- (2018) Michela Guglielmotto et al. JOURNAL OF ALZHEIMERS DISEASE
- JNK3 as a Therapeutic Target for Neurodegenerative Diseases
- (2018) Xanthi Antoniou et al. JOURNAL OF ALZHEIMERS DISEASE
- Strategies, Development, and Pitfalls of Therapeutic Options for Alzheimer's Disease
- (2018) Christopher Haas JOURNAL OF ALZHEIMERS DISEASE
- Movement disorder society criteria for clinically established early Parkinson's disease
- (2018) Daniela Berg et al. MOVEMENT DISORDERS
- Diagnosis and management of dementia with Lewy bodies
- (2017) Ian G. McKeith et al. NEUROLOGY
- Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System
- (2017) Diego Pignataro et al. Frontiers in Neuroanatomy
- Down-regulation of glutamatergic terminals (VGLUT1) driven by Aβ in Alzheimer's disease
- (2016) Manuel Rodriguez-Perdigon et al. HIPPOCAMPUS
- c-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer’s Disease
- (2016) Ramon Yarza et al. Frontiers in Pharmacology
- B2 receptor blockage prevents Aβ-induced cognitive impairment by neuroinflammation inhibition
- (2015) M.A. Bicca et al. BEHAVIOURAL BRAIN RESEARCH
- Induction of GADD34 Regulates the Neurotoxicity of Amyloid β
- (2014) Niangui Xu et al. American Journal of Alzheimers Disease and Other Dementias
- Neuroprotective effects of diarylpropionitrile against β-amyloid peptide-induced neurotoxicity in rat cultured cortical neurons
- (2014) Nirut Suwanna et al. NEUROSCIENCE LETTERS
- Amyloid-β and Tau
- (2014) George S. Bloom JAMA Neurology
- Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series
- (2013) Gabor G. Kovacs et al. ACTA NEUROPATHOLOGICA
- Proteolytic Cleavage of Polymeric Tau Protein by Caspase-3: Implications for Alzheimer Disease
- (2013) Jose J. Jarero-Basulto et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Neuroprotective Effects of Resveratrol Against Aβ Administration in Rats are Improved by Lipid-Core Nanocapsules
- (2013) Rudimar L. Frozza et al. MOLECULAR NEUROBIOLOGY
- Inhibition of JNK by a Peptide Inhibitor Reduces Traumatic Brain Injury–Induced Tauopathy in Transgenic Mice
- (2012) Hien T. Tran et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- JNK3 Perpetuates Metabolic Stress Induced by Aβ Peptides
- (2012) Sung Ok Yoon et al. NEURON
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Classification and basic pathology of Alzheimer disease
- (2009) Charles Duyckaerts et al. ACTA NEUROPATHOLOGICA
- Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3β is required for tau aggregation
- (2008) Naruhiko Sahara et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s disease
- (2008) Siddhartha Mondragón-Rodríguez et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Inhibitors of c-Jun N-terminal kinases—JuNK no more?
- (2007) Marie A. Bogoyevitch et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started