A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC

Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC

(2022) Robert Saddawi-Konefka et al.   Nature Communications

A comparative study of evaluating missing value imputation methods in label-free proteomics

(2021) Liang Jin et al.   Scientific Reports

Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells

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The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality

(2021) Aaron Issaian et al.   HAEMATOLOGICA

Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis

(2021) Michael W Knitz et al.   Journal for ImmunoTherapy of Cancer

Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma

(2021) Rom Leidner et al.   Journal for ImmunoTherapy of Cancer

MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights

(2021) Zhiqiang Pang et al.   NUCLEIC ACIDS RESEARCH

Statistical and machine learning methods for analysis of multiplex protein data from a novel proximity extension assay in patients with ST-elevation myocardial infarction

(2021) Emil Maag et al.   Scientific Reports

Overcoming Resistance to Immunotherapy in Head and Neck Cancer Using Radiation: A Review

(2021) Caressa Hui et al.   Frontiers in Oncology

Solid stress impairs lymphocyte infiltration into lymph-node metastases

(2021) Dennis Jones et al.   Nature Biomedical Engineering

Hematologic and systemic metabolic alterations due to Mediterranean class II G6PD deficiency in mice

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Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma

(2021) Joris L. Vos et al.   Nature Communications

Concurrent definitive immunoradiotherapy for patients with Stage III-IV Head and Neck Cancer and Cisplatin contraindication

(2020) Jared Weiss et al.   CLINICAL CANCER RESEARCH

Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicenter, Phase 2 Trial

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Head and Neck Cancers, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology

(2020) David G. Pfister et al.   Journal of the National Comprehensive Cancer Network

Randomized Phase II Trial of Nivolumab With Stereotactic Body Radiotherapy Versus Nivolumab Alone in Metastatic Head and Neck Squamous Cell Carcinoma

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PD-1+ Treg cells: a foe in cancer immunotherapy?

(2020) Halil-Ibrahim Aksoylar et al.   NATURE IMMUNOLOGY

Neoadjuvant Nivolumab or Nivolumab Plus Ipilimumab in Untreated Oral Cavity Squamous Cell Carcinoma

(2020) Jonathan D. Schoenfeld et al.   JAMA Oncology

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(2020) Daniel E. Johnson et al.   Nature Reviews Disease Primers

Blood donor exposome and impact of common drugs on red blood cell metabolism

(2020) Travis Nemkov et al.   JCI Insight

The role of regulatory T cells in the response to radiation therapy in head and neck cancer

(2019) Ayman J Oweida et al.   JNCI-Journal of the National Cancer Institute

MultiPLIER: A Transfer Learning Framework for Transcriptomics Reveals Systemic Features of Rare Disease

(2019) Jaclyn N. Taroni et al.   Cell Systems

Tumor-Infiltrating Lymphocyte Volume Is a Better Predictor of Disease-Free Survival Than Stromal Tumor-Infiltrating Lymphocytes in Invasive Breast Carcinoma

(2019) Elmira Vaziri Fard et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Clonal replacement of tumor-specific T cells following PD-1 blockade

(2019) Kathryn E. Yost et al.   NATURE MEDICINE

Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study

(2019) Barbara Burtness et al.   LANCET

MHC-II neoantigens shape tumour immunity and response to immunotherapy

(2019) Elise Alspach et al.   NATURE

First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low-dose Cyclophosphamide in Patients with Advanced Malignancies

(2019) Kyriakos P. Papadopoulos et al.   CLINICAL CANCER RESEARCH

Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors

(2018) Thomas Duhen et al.   Nature Communications

The Role of Lipid Metabolism in T Lymphocyte Differentiation and Survival

(2018) Duncan Howie et al.   Frontiers in Immunology

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

(2018) Sanjeev Mariathasan et al.   NATURE

Biological Consequences of Major Histocompatibility Class-II Expression by Tumor Cells in Cancer

(2018) Margaret L Axelrod et al.   CLINICAL CANCER RESEARCH

JAVELIN Head and Neck 100: a Phase III trial of avelumab and chemoradiation for locally advanced head and neck cancer

(2018) Yao Yu et al.   Future Oncology

Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study

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Radiotherapy induces responses of lung cancer to CTLA-4 blockade

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DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

(2017) Claire Vanpouille-Box et al.   Nature Communications

Ionizing radiation sensitizes tumors to PD-L1 immune checkpoint blockade in orthotopic murine head and neck squamous cell carcinoma

(2017) Ayman Oweida et al.   OncoImmunology

Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)

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Targeting cellular and molecular drivers of head and neck squamous cell carcinoma: current options and emerging perspectives

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Fine-Tuning of CD8 + T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus

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Fractionated Radiotherapy with 3 x 8 Gy Induces Systemic Anti-Tumour Responses and Abscopal Tumour Inhibition without Modulating the Humoral Anti-Tumour Response

(2016) Thomas H. P. M. Habets et al.   PLoS One

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

(2015) Sebastian Kreiter et al.   NATURE

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(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

The antitumor immune response generated by fractionated radiation therapy may be limited by tumor cell adaptive resistance and can be circumvented by PD-L1 blockade

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Randomized Phase III Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Stage III to IV Head and Neck Carcinoma: RTOG 0522

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Harnessing the Heterogeneity of T Cell Differentiation Fate to Fine-Tune Generation of Effector and Memory T Cells

(2014) Chang Gong et al.   Frontiers in Immunology

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Maximizing Tumor Immunity With Fractionated Radiation

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(2011) Christian Frezza et al.   NATURE

Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors

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Missing data imputation using statistical and machine learning methods in a real breast cancer problem

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MHC II lung cancer vaccines prime and boost tumor-specific CD4+ T cells that cross-react with multiple histologic subtypes of nonsmall cell lung cancer cells

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Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

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Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

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