标题
The cGAS–STING pathway and cancer
作者
关键词
-
出版物
Nature Cancer
Volume 3, Issue 12, Pages 1452-1463
出版商
Springer Science and Business Media LLC
发表日期
2022-12-13
DOI
10.1038/s43018-022-00468-w
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Emerging dimensions of cellular cGAS-STING signaling
- (2022) Baptiste Guey et al. CURRENT OPINION IN IMMUNOLOGY
- The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
- (2022) Jeremy Di Domizio et al. NATURE
- The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING–p53 signaling
- (2022) Axel R. Concepcion et al. NATURE IMMUNOLOGY
- Breakage of cytoplasmic chromosomes by pathological DNA base excision repair
- (2022) Shangming Tang et al. NATURE
- STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity
- (2022) Eric L. Dane et al. NATURE MATERIALS
- ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP
- (2022) Joanna H. Maltbaek et al. IMMUNITY
- ER-directed TREX1 limits cGAS activation at micronuclei
- (2021) Lisa Mohr et al. MOLECULAR CELL
- mRNA-encoded, constitutively active STINGV155M is a potent genetic adjuvant of antigen-specific CD8+ T cell response
- (2021) Sze-Wah Tse et al. MOLECULAR THERAPY
- The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
- (2021) Álvaro de Mingo Pulido et al. IMMUNITY
- TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections
- (2021) Seoyun Yum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance
- (2021) Su Chul Jang et al. Communications Biology
- Translation stress and collided ribosomes are co-activators of cGAS
- (2021) Li Wan et al. MOLECULAR CELL
- cGAS restricts colon cancer development by protecting intestinal barrier integrity
- (2021) Shuiqing Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human SLC46A2 Is the Dominant cGAMP Importer in Extracellular cGAMP-Sensing Macrophages and Monocytes
- (2021) Anthony F. Cordova et al. ACS Central Science
- eccDNAs are apoptotic products with high innate immunostimulatory activity
- (2021) Yuangao Wang et al. NATURE
- Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells
- (2021) Patrick J. Flynn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interplay of cGAS with chromatin
- (2021) Marilena Wischnewski et al. TRENDS IN BIOCHEMICAL SCIENCES
- Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants
- (2021) Enrique Conde et al. Journal for ImmunoTherapy of Cancer
- Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
- (2020) Yi Zhou et al. IMMUNITY
- Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
- (2020) Chun Zhou et al. IMMUNITY
- The clearance of dead cells by efferocytosis
- (2020) Emilio Boada-Romero et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Molecular mechanisms and cellular functions of cGAS–STING signalling
- (2020) Karl-Peter Hopfner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity
- (2020) Ilgen Mender et al. CANCER CELL
- Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion
- (2020) Jianjun Wu et al. IMMUNITY
- Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy
- (2020) Xueguang Lu et al. Science Translational Medicine
- The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS
- (2020) Baoyu Zhao et al. NATURE
- Structural basis for sequestration and autoinhibition of cGAS by chromatin
- (2020) Sebastian Michalski et al. NATURE
- Structural mechanism of cGAS inhibition by the nucleosome
- (2020) Ganesh R. Pathare et al. NATURE
- BAF restricts cGAS on nuclear DNA to prevent innate immune activation
- (2020) Baptiste Guey et al. SCIENCE
- Structural basis for the inhibition of cGAS by nucleosomes
- (2020) Tomoya Kujirai et al. SCIENCE
- Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity
- (2020) Henrique Lemos et al. Journal for ImmunoTherapy of Cancer
- MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway
- (2020) Junhong Guan et al. CANCER CELL
- STING agonist promotes CAR T cell trafficking and persistence in breast cancer
- (2020) Nuo Xu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Metastasis and immune evasion from extracellular cGAMP hydrolysis
- (2020) Jun Li et al. Cancer Discovery
- Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy
- (2019) Daniel Shae et al. Nature Nanotechnology
- Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer
- (2019) Triparna Sen et al. Cancer Discovery
- L1 drives IFN in senescent cells and promotes age-associated inflammation
- (2019) Marco De Cecco et al. NATURE
- Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
- (2019) Xiang Gui et al. NATURE
- Autophagic cell death restricts chromosomal instability during replicative crisis
- (2019) Joe Nassour et al. NATURE
- STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death
- (2019) Jianjun Wu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Phase Ib study of MIW815 (ADU-S100) in combination with spartalizumab (PDR001) in patients (pts) with advanced/metastatic solid tumors or lymphomas.
- (2019) Funda Meric-Bernstam et al. JOURNAL OF CLINICAL ONCOLOGY
- Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS
- (2019) Matthieu Gratia et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SLC19A1 Is an Importer of the Immunotransmitter cGAMP
- (2019) Christopher Ritchie et al. MOLECULAR CELL
- Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models
- (2019) Mona Motwani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer
- (2019) Constantia Pantelidou et al. Cancer Discovery
- ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage
- (2019) Jessica Willan et al. Oncogenesis
- The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death
- (2019) Christian Zierhut et al. CELL
- STING pathway agonism as a cancer therapeutic
- (2019) Blake A. Flood et al. IMMUNOLOGICAL REVIEWS
- SLC19A1 transports immunoreactive cyclic dinucleotides
- (2019) Rutger D. Luteijn et al. NATURE
- Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation
- (2019) Lei Miao et al. NATURE BIOTECHNOLOGY
- Harnessing innate immunity in cancer therapy
- (2019) Olivier Demaria et al. NATURE
- Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity
- (2019) Linda Schadt et al. Cell Reports
- Regulation of cGAS- and RLR-mediated immunity to nucleic acids
- (2019) Andrea Ablasser et al. NATURE IMMUNOLOGY
- Tight nuclear tethering of cGAS is essential for preventing autoreactivity
- (2019) Hannah E Volkman et al. eLife
- Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy
- (2018) David R. Wilson et al. Nanomedicine-Nanotechnology Biology and Medicine
- Chromosomal instability drives metastasis through a cytosolic DNA response
- (2018) Samuel F. Bakhoum et al. NATURE
- Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses
- (2018) Israel Cañadas et al. NATURE MEDICINE
- Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production
- (2018) Hiroyasu Konno et al. ONCOGENE
- Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells
- (2018) Akiko Takahashi et al. Nature Communications
- TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors
- (2018) Brian J. Francica et al. Cancer Immunology Research
- LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance
- (2018) Larissa D. Cunha et al. CELL
- Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
- (2018) Yuzhu Hou et al. IMMUNITY
- Targeting STING with covalent small-molecule inhibitors
- (2018) Simone M. Haag et al. NATURE
- SAMHD1 acts at stalled replication forks to prevent interferon induction
- (2018) Flavie Coquel et al. NATURE
- LBA15Preliminary results of the first-in-human (FIH) study of MK-1454, an agonist of stimulator of interferon genes (STING), as monotherapy or in combination with pembrolizumab (pembro) in patients with advanced solid tumors or lymphomas
- (2018) K J Harrington et al. ANNALS OF ONCOLOGY
- STING promotes homeostasis via regulation of cell proliferation and chromosomal stability
- (2018) Diana Rose E. Ranoa et al. CANCER RESEARCH
- PARPi Triggers the STING-Dependent Immune Response and Enhances the Therapeutic Efficacy of Immune Checkpoint Blockade Independent of BRCAness
- (2018) Jianfeng Shen et al. CANCER RESEARCH
- Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
- (2018) Assaf Marcus et al. IMMUNITY
- Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
- (2018) Haipeng Liu et al. NATURE
- Design of amidobenzimidazole STING receptor agonists with systemic activity
- (2018) Joshi M. Ramanjulu et al. NATURE
- Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer
- (2018) Shunsuke Kitajima et al. Cancer Discovery
- PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer
- (2018) Liya Ding et al. Cell Reports
- Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity
- (2018) Kelsey E. Sivick et al. Cell Reports
- PARP inhibition enhances tumor cell–intrinsic immunity in ERCC1-deficient non–small cell lung cancer
- (2018) Roman M. Chabanon et al. JOURNAL OF CLINICAL INVESTIGATION
- A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1
- (2017) Erkin Erdal et al. GENES & DEVELOPMENT
- Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling
- (2017) Meng Michelle Xu et al. IMMUNITY
- Tissue-Resident Macrophages Are Locally Programmed for Silent Clearance of Apoptotic Cells
- (2017) Allison W. Roberts et al. IMMUNITY
- Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes
- (2017) Silvia Cerboni et al. JOURNAL OF EXPERIMENTAL MEDICINE
- STING-associated vasculopathy develops independently of IRF3 in mice
- (2017) James D. Warner et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death
- (2017) Bridget Larkin et al. JOURNAL OF IMMUNOLOGY
- Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity
- (2017) Kristen M. Turner et al. NATURE
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Mitotic progression following DNA damage enables pattern recognition within micronuclei
- (2017) Shane M. Harding et al. NATURE
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
- (2017) Zhixun Dou et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway
- (2017) Yi-An Chen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- cGAS is essential for the antitumor effect of immune checkpoint blockade
- (2017) Hua Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cGAS is essential for cellular senescence
- (2017) Hui Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Host STING-dependent MDSC mobilization drives extrinsic radiation resistance
- (2017) Hua Liang et al. Nature Communications
- Signalling strength determines proapoptotic functions of STING
- (2017) Muhammet F. Gulen et al. Nature Communications
- Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice
- (2017) Jessica Vincent et al. Nature Communications
- DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
- (2017) Claire Vanpouille-Box et al. Nature Communications
- Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway
- (2017) Yi-An Chen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Decreased expression of STING predicts poor prognosis in patients with gastric cancer
- (2017) Shushu Song et al. Scientific Reports
- Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response
- (2017) Vijay K. Gonugunta et al. Cell Reports
- STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation
- (2016) Henrique Lemos et al. CANCER RESEARCH
- Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
- (2016) Karen J Mackenzie et al. EMBO JOURNAL
- The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells
- (2016) Samantha S.W. Ho et al. IMMUNITY
- Growing tumors induce a local STING dependent Type I IFN response in dendritic cells
- (2016) Lisa Andzinski et al. INTERNATIONAL JOURNAL OF CANCER
- Nuclear envelope rupture is induced by actin-based nucleus confinement
- (2016) Emily M. Hatch et al. JOURNAL OF CELL BIOLOGY
- Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
- (2016) Qing Chen et al. NATURE
- Activation of STING requires palmitoylation at the Golgi
- (2016) Kojiro Mukai et al. Nature Communications
- Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response
- (2016) Tiejun Li et al. Scientific Reports
- Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
- (2016) Tianli Xia et al. Cell Reports
- STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia
- (2016) Emily Curran et al. Cell Reports
- Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors
- (2015) J. R. Baird et al. CANCER RESEARCH
- Chromothripsis and Kataegis Induced by Telomere Crisis
- (2015) John Maciejowski et al. CELL
- DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
- (2015) David Roulois et al. CELL
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
- (2015) Anetta Härtlova et al. IMMUNITY
- Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi–Goutières Syndrome
- (2015) Elizabeth E. Gray et al. JOURNAL OF IMMUNOLOGY
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- Control of adaptive immunity by the innate immune system
- (2015) Akiko Iwasaki et al. NATURE IMMUNOLOGY
- CD47 blockade triggers T cell–mediated destruction of immunogenic tumors
- (2015) Xiaojuan Liu et al. NATURE MEDICINE
- Suppression of systemic autoimmunity by the innate immune adaptor STING
- (2015) Shruti Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
- (2015) Olivier Demaria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
- (2015) Daxing Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection
- (2015) Megan H. Orzalli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Viruses transfer the antiviral second messenger cGAMP between cells
- (2015) A. Bridgeman et al. SCIENCE
- Transmission of innate immune signaling by packaging of cGAMP in viral particles
- (2015) Matteo Gentili et al. SCIENCE
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
- (2015) Leticia Corrales et al. Cell Reports
- RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
- (2014) Adeline R. Lam et al. CANCER RESEARCH
- STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
- (2014) Seng-Ryong Woo et al. IMMUNITY
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- STING-Mediated DNA Sensing Promotes Antitumor and Autoimmune Responses to Dying Cells
- (2014) Jared Klarquist et al. JOURNAL OF IMMUNOLOGY
- Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis
- (2014) H. Lemos et al. JOURNAL OF IMMUNOLOGY
- TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner
- (2014) A. Ablasser et al. JOURNAL OF IMMUNOLOGY
- Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs
- (2014) Lingyin Li et al. Nature Chemical Biology
- Activated STING in a Vascular and Pulmonary Syndrome
- (2014) Yin Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inflammation-driven carcinogenesis is mediated through STING
- (2014) Jeonghyun Ahn et al. Nature Communications
- STING Contributes to Antiglioma Immunity via Triggering Type I IFN Signals in the Tumor Microenvironment
- (2014) T. Ohkuri et al. Cancer Immunology Research
- STING Ligand c-di-GMP Improves Cancer Vaccination against Metastatic Breast Cancer
- (2014) D. Chandra et al. Cancer Immunology Research
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei
- (2013) Emily M. Hatch et al. CELL
- Lysosome-mediated processing of chromatin in senescence
- (2013) Andre Ivanov et al. JOURNAL OF CELL BIOLOGY
- Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses
- (2013) L. Huang et al. JOURNAL OF IMMUNOLOGY
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
- (2013) Andrea Ablasser et al. NATURE
- STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
- (2013) J. Petrasek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- DNA breaks and chromosome pulverization from errors in mitosis
- (2012) Karen Crasta et al. NATURE
- Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
- (2012) J. Wu et al. SCIENCE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells
- (2011) Mercedes B. Fuertes et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Type I interferon is selectively required by dendritic cells for immune rejection of tumors
- (2011) Mark S. Diamond et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
- (2011) Tae-Won Kang et al. NATURE
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
- (2008) R. R. Weichselbaum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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