Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose

Glucose Activates TORC2-Gad8 Protein via Positive Regulation of the cAMP/cAMP-dependent Protein Kinase A (PKA) Pathway and Negative Regulation of the Pmk1 Protein-Mitogen-activated Protein Kinase Pathway

(2014) Adiel Cohen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutionarily conserved regulation of TOR signalling

(2013) T. Takahara et al.   JOURNAL OF BIOCHEMISTRY

Autoregulation of the Mechanistic Target of Rapamycin (mTOR) Complex 2 Integrity Is Controlled by an ATP-dependent Mechanism

(2013) Chien-Hung Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of the TOR ATP binding domain by AGC kinase constitutes a novel mode of TOR inhibition

(2013) Lenka Hálová et al.   JOURNAL OF CELL BIOLOGY

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

(2013) Christian C. Dibble et al.   NATURE CELL BIOLOGY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Regulation of TOR by small GTPases

(2012) Raúl V Durán et al.   EMBO REPORTS

TORC1 of fission yeast is rapamycin-sensitive

(2012) Terunao Takahara et al.   GENES TO CELLS

Psk1, an AGC kinase family member in fission yeast, is directly phosphorylated and controlled by TORC1 and functions as S6 kinase

(2012) A. Nakashima et al.   JOURNAL OF CELL SCIENCE

Activation of mTORC2 by Association with the Ribosome

(2011) Vittoria Zinzalla et al.   CELL

mTOR complex 2 signaling and functions

(2011) Won Jun Oh et al.   CELL CYCLE

Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast

(2011) Tomáš Pluskal et al.   FEBS Journal

Evidence for Direct Activation of mTORC2 Kinase Activity by Phosphatidylinositol 3,4,5-Trisphosphate

(2011) Xiaoqing Gan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe

(2011) N. Ikai et al.   Open Biology

Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control

(2010) Kyoko Ikeda et al.   CELL CYCLE

Rab-Family GTPase Regulates TOR Complex 2 Signaling in Fission Yeast

(2010) Hisashi Tatebe et al.   CURRENT BIOLOGY

Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin

(2010) A. Nakashima et al.   JOURNAL OF CELL SCIENCE

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy-deficient Schizosaccharomyces pombe mutants undergo partial sporulation during nitrogen starvation

(2009) H. Mukaiyama et al.   MICROBIOLOGY-SGM

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TOR regulation of AGC kinases in yeast and mammals

(2008) Estela Jacinto et al.   BIOCHEMICAL JOURNAL

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

(2008) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

TOR Signaling in Fission Yeast

(2008) Yoko Otsubo et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

(2008) Tsuneo Ikenoue et al.   EMBO JOURNAL

Biophysical Analysis of the Interaction of Rab6a GTPase with Its Effector Domains

(2008) Tim Bergbrede et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY