The injured sciatic nerve atlas (iSNAT), insights into the cellular and molecular basis of neural tissue degeneration and regeneration

Immunomodulatory effects of mesenchymal stem cells in peripheral nerve injury

(2022) Xiangling Li et al.   Stem Cell Research & Therapy

Multifaceted roles of SARM1 in axon degeneration and signaling

(2022) Thomas J. Waller et al.   Frontiers in Cellular Neuroscience

Inference and analysis of cell-cell communication using CellChat

(2021) Suoqin Jin et al.   Nature Communications

Modeling the energy metabolism in immune cells

(2021) Stefan Schuster et al.   CURRENT OPINION IN BIOTECHNOLOGY

Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration

(2021) Bing Chen et al.   Frontiers in Cellular Neuroscience

Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT)

(2021) Daniel Gerber et al.   eLife

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Metabolic orchestration of the wound healing response

(2021) Sabine A. Eming et al.   Cell Metabolism

Dendritic cell migration in inflammation and immunity

(2021) Juan Liu et al.   Cellular & Molecular Immunology

The SARM1 TIR NADase: Mechanistic Similarities to Bacterial Phage Defense and Toxin-Antitoxin Systems

(2021) Aaron DiAntonio et al.   Frontiers in Immunology

eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity

(2021) Tracy L. Smith et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cytotoxic Immunity in Peripheral Nerve Injury and Pain

(2020) Alexander J. Davies et al.   Frontiers in Neuroscience

Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

(2020) Elke Ydens et al.   NATURE NEUROSCIENCE

The clearance of dead cells by efferocytosis

(2020) Emilio Boada-Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Programmed axon degeneration: from mouse to mechanism to medicine

(2020) Michael P. Coleman et al.   NATURE REVIEWS NEUROSCIENCE

Regulatory T cells counteract neuropathic pain through inhibition of the Th1 response at the site of peripheral nerve injury

(2020) Marcela Davoli-Ferreira et al.   PAIN

Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity

(2020) Jolien Wolbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia

(2020) Peter L. Wang et al.   Nature Communications

Glial Metabolic Rewiring Promotes Axon Regeneration and Functional Recovery in the Central Nervous System

(2020) Feng Li et al.   Cell Metabolism

The Role of HIF in Immunity and Inflammation

(2020) Anne F. McGettrick et al.   Cell Metabolism

The CCL2/CCR2 axis is critical to recruiting macrophages into acellular nerve allograft bridging a nerve gap to promote angiogenesis and regeneration

(2020) Deng Pan et al.   EXPERIMENTAL NEUROLOGY

A glycolytic shift in Schwann cells supports injured axons

(2020) Elisabetta Babetto et al.   NATURE NEUROSCIENCE

Single-cell RNA sequencing uncovers heterogenous transcriptional signatures in macrophages during efferocytosis

(2020) Connor Lantz et al.   Scientific Reports

Oncometabolites lactate and succinate drive pro-angiogenic macrophage response in tumors

(2020) Marjolein M.G. Kes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement

(2020) Ashley L Kalinski et al.   eLife

The oncogenic and clinical implications of lactate induced immunosuppression in the tumour microenvironment

(2020) Conall Hayes et al.   CANCER LETTERS

Soluble CD93 is an apoptotic cell opsonin recognized by αx β2

(2019) Jack W.D. Blackburn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance

(2019) Ayako Nagao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

(2019) Svetoslav Chakarov et al.   SCIENCE

Neutrophil–macrophage cooperation and its impact on tissue repair

(2019) Tiffany Bouchery et al.   IMMUNOLOGY AND CELL BIOLOGY

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

(2019) Sebastiaan De Schepper et al.   CELL

Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury

(2019) Alexander J. Davies et al.   CELL

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

The Role of Endothelial Dysfunction in Peripheral Blood Nerve Barrier: Molecular Mechanisms and Pathophysiological Implications

(2019) Jessica Maiuolo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Soluble defense collagens: Sweeping up immune threats

(2019) Cristina Casals et al.   MOLECULAR IMMUNOLOGY

The molecular interplay between axon degeneration and regeneration

(2018) Marie-Pier Girouard et al.   Developmental Neurobiology

Comparative analysis of the transcriptome of injured nerve segments reveals spatiotemporal responses to neural damage in mice

(2018) Jung Eun Shin et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Lactate transport facilitates neurite outgrowth

(2018) Kun Chen et al.   BIOSCIENCE REPORTS

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

(2018) Evanna L. Mills et al.   NATURE

Macrophages Regulate Schwann Cell Maturation after Nerve Injury

(2018) Jo Anne Stratton et al.   Cell Reports

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

(2018) Shuang Zhang et al.   Cell Metabolism

Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration

(2018) Matthew J. Carr et al.   Cell Stem Cell

Getting TANned: How the tumor microenvironment drives neutrophil recruitment

(2018) Shuvasree SenGupta et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

(2018) Sho Morioka et al.   NATURE

The long pentraxin PTX3: A prototypical sensor of tissue injury and a regulator of homeostasis

(2017) Marco Erreni et al.   IMMUNOLOGICAL REVIEWS

Neutrophils Are Critical for Myelin Removal in a Peripheral Nerve Injury Model of Wallerian Degeneration

(2017) Jane A. Lindborg et al.   JOURNAL OF NEUROSCIENCE

Conformational Changes in C-Reactive Protein Affect Binding to Curved Membranes in a Lipid Bilayer Model of the Apoptotic Cell Surface

(2017) Aml A. Alnaas et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Inflammation and metabolism in tissue repair and regeneration

(2017) Sabine A. Eming et al.   SCIENCE

Impaired Axonal Regeneration in Diabetes. Perspective on the Underlying Mechanism from In Vivo and In Vitro Experimental Studies

(2017) Kazunori Sango et al.   Frontiers in Endocrinology

Myelin and macrophages in the PNS: An intimate relationship in trauma and disease

(2016) Dennis Klein et al.   BRAIN RESEARCH

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

(2016) Vicky Lampropoulou et al.   Cell Metabolism

Clearance of apoptotic neutrophils and resolution of inflammation

(2016) Mallary C. Greenlee-Wacker   IMMUNOLOGICAL REVIEWS

Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy

(2016) Md Habibur Rahman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF1α and metabolic reprogramming in inflammation

(2016) Sarah E. Corcoran et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury

(2015) Peiwen Chen et al.   ACTA NEUROPATHOLOGICA

Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves

(2015) Anne-Laure Cattin et al.   CELL

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

(2015) Eva M. Palsson-McDermott et al.   Cell Metabolism

Autophagic myelin destruction by schwann cells during wallerian degeneration and segmental demyelination

(2015) So Young Jang et al.   GLIA

Novel insights into the immunomodulatory role of the dendritic cell and macrophage-expressed C-type lectin MGL

(2015) Yvette van Kooyk et al.   IMMUNOBIOLOGY

Cytokine pathways regulating glial and leukocyte function after spinal cord and peripheral nerve injury

(2014) Dominic Bastien et al.   EXPERIMENTAL NEUROLOGY

Cellular Metabolism and Macrophage Functional Polarization

(2014) Linnan Zhu et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

SARM Regulates CCL5 Production in Macrophages by Promoting the Recruitment of Transcription Factors and RNA Polymerase II to the Ccl5 Promoter

(2014) C. Gurtler et al.   JOURNAL OF IMMUNOLOGY

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

In Vivo Nerve-Macrophage Interactions Following Peripheral Nerve Injury

(2012) A. F. Rosenberg et al.   JOURNAL OF NEUROSCIENCE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

A Central Role for the ERK-Signaling Pathway in Controlling Schwann Cell Plasticity and Peripheral Nerve Regeneration In Vivo

(2012) Ilaria Napoli et al.   NEURON

dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway

(2012) J. M. Osterloh et al.   SCIENCE

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

PTX3 Is Located at the Membrane of Late Apoptotic Macrophages and Mediates the Phagocytosis of Macrophages

(2011) Tangmeng Guo et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Wallerian degeneration: the innate-immune response to traumatic nerve injury

(2011) Shlomo Rotshenker   Journal of Neuroinflammation

Saturated-efferocytosis generates pro-resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids

(2010) Sagie Schif-Zuck et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential gene expression analysis identifies murine Cacnb3 as strongly upregulated in distinct dendritic cell populations upon stimulation

(2010) Matthias Bros et al.   GENE

Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury

(2010) M. E. Vargas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

(2009) R. G. Jenner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA