Structural and biochemical characterization of Leptospira interrogans Lsa45 reveals a penicillin-binding protein with esterase activity

Leptospirosis: clinical aspects

(2022) Senaka Rajapakse   CLINICAL MEDICINE

Dual functional roles of a novel bifunctional β-lactamase/esterase from Lactococcus garvieae

(2022) Ly Thi Huong Luu Le et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Strengthening of enterococcal biofilms by Esp

(2022) Lindsey Spiegelman et al.   PLoS Pathogens

A Review on Host-Leptospira Interactions: What We Know and Future Expectations

(2021) Brenda B. Daroz et al.   Frontiers in Cellular and Infection Microbiology

Coevolved Positions Represent Key Functional Properties in the Trypsin-Like Serine Proteases Protein Family

(2020) Marcelo Querino Lima Afonso et al.   Journal of Chemical Information and Modeling

Isolation and propagation of leptospires at 37 °C directly from the mammalian host

(2020) Richard L. Hornsby et al.   Scientific Reports

Repurposing an Ancient Protein Core Structure: Structural Studies on FmtA, a Novel Esterase of Staphylococcus aureus

(2019) Vikram Dalal et al.   JOURNAL OF MOLECULAR BIOLOGY

First Penicillin-Binding Protein Occupancy Patterns of β-Lactams and β-Lactamase Inhibitors in Klebsiella pneumoniae

(2018) Dhruvitkumar S. Sutaria et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

How large B-factors can be in protein crystal structures

(2018) Oliviero Carugo   BMC BIOINFORMATICS

SAXSMoW 2.0: Online calculator of the molecular weight of proteins in dilute solution from experimental SAXS data measured on a relative scale

(2018) Vassili Piiadov et al.   PROTEIN SCIENCE

Leptospira spp.: Novel insights into host–pathogen interactions

(2016) Luis G. Fernandes et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Biochemical and Structural Analysis of a Novel Esterase from Caulobacter crescentus related to Penicillin-Binding Protein (PBP)

(2016) Bum Han Ryu et al.   Scientific Reports

FIT2D: a multi-purpose data reduction, analysis and visualization program

(2016) A. P. Hammersley   JOURNAL OF APPLIED CRYSTALLOGRAPHY

A novel family VIII carboxylesterase hydrolysing third- and fourth-generation cephalosporins

(2016) Jeong Ho Jeon et al.   SpringerPlus

Structural and computational analysis of peptide recognition mechanism of class-C type penicillin binding protein, alkaline D-peptidase from Bacillus cereus DF4-B

(2015) Shogo Nakano et al.   Scientific Reports

Biochemical and Structural Analysis of Inhibitors Targeting the ADC-7 Cephalosporinase of Acinetobacter baumannii

(2014) Rachel A. Powers et al.   BIOCHEMISTRY

Crystal structure analysis of EstA fromArthrobactersp. Rue61a - an insight into catalytic promiscuity

(2014) Ulrike Gabriella Wagner et al.   FEBS LETTERS

Efficacy of cefepime, ertapenem and norfloxacin against leptospirosis and for the clearance of pathogens in a hamster model

(2014) Wenlong Zhang et al.   MICROBIAL PATHOGENESIS

Evolution of Conformational Dynamics Determines the Conversion of a Promiscuous Generalist into a Specialist Enzyme

(2014) T. Zou et al.   MOLECULAR BIOLOGY AND EVOLUTION

Crystallographic analysis and biochemical applications of a novel penicillin-binding protein/β-lactamase homologue from a metagenomic library

(2014) Tri Duc Ngo et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

ThePDB_REDOserver for macromolecular structure model optimization

(2014) Robbie P. Joosten et al.   IUCrJ

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structures of Bifunctional Penicillin-Binding Protein 4 from Listeria monocytogenes

(2013) Jae-Hee Jeong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC β-Lactamases

(2013) Sushmita D. Lahiri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Functional characterisation of a metagenome derived family VIII esterase with a deacetylation activity on β-lactam antibiotics

(2013) Nobalanda Mokoena et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

(2013) L. H. Otero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for the β-lactamase activity of EstU1, a family VIII carboxylesterase

(2013) Sun-Shin Cha et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structural analysis of the Asn152Gly mutant of P99 cephalosporinase

(2012) James F. Ruble et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

In Vitro and In Vivo Activity of First Generation Cephalosporins Against Leptospira

(2011) Brande M. Harris et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Novel Metagenome-Derived Carboxylesterase That Hydrolyzes β-Lactam Antibiotics

(2011) Jeong Ho Jeon et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Emergence, control and re-emerging leptospirosis: dynamics of infection in the changing world

(2011) R.A. Hartskeerl et al.   CLINICAL MICROBIOLOGY AND INFECTION

Using Amino Acid Correlation and Community Detection Algorithms to Identify Functional Determinants in Protein Families

(2011) Lucas Bleicher et al.   PLoS One

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Decision-making in structure solution using Bayesian estimates of map quality: thePHENIX AutoSolwizard

(2009) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A novel family VIII carboxylesterase derived from a leachate metagenome library exhibits promiscuous β-lactamase activity on nitrocefin

(2009) Konanani Rashamuse et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Roll: a new algorithm for the detection of protein pockets and cavities with a rolling probe sphere

(2009) Jian Yu et al.   BIOINFORMATICS

Structural Bases for Stability–Function Tradeoffs in Antibiotic Resistance

(2009) Veena L. Thomas et al.   JOURNAL OF MOLECULAR BIOLOGY

Re-examining the role of Lys67 in class C β-lactamase catalysis

(2009) Yu Chen et al.   PROTEIN SCIENCE

Leptospira and leptospirosis

(2009) Ben Adler et al.   VETERINARY MICROBIOLOGY

EstB from Burkholderia gladioli: A novel esterase with a β-lactamase fold reveals steric factors to discriminate between esterolytic and β-lactam cleaving activity

(2002) Ulrike G. Wagner et al.   PROTEIN SCIENCE