PD-1 signalling defines and protects leukaemic stem cells from T cell receptor-induced cell death in T cell acute lymphoblastic leukaemia
出版年份 2023 全文链接
标题
PD-1 signalling defines and protects leukaemic stem cells from T cell receptor-induced cell death in T cell acute lymphoblastic leukaemia
作者
关键词
-
出版物
NATURE CELL BIOLOGY
Volume 25, Issue 1, Pages 170-182
出版商
Springer Science and Business Media LLC
发表日期
2023-01-10
DOI
10.1038/s41556-022-01050-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia
- (2022) William Grey et al. Science Translational Medicine
- Targeting Energy Metabolism in Cancer Stem Cells: Progress and Challenges in Leukemia and Solid Tumors
- (2021) Courtney L. Jones et al. Cell Stem Cell
- Overcoming Wnt–β-catenin dependent anticancer therapy resistance in leukaemia stem cells
- (2020) John M. Perry et al. NATURE CELL BIOLOGY
- CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
- (2019) Laura M. McLane et al. Annual Review of Immunology
- Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion
- (2019) Anna M. Paczulla et al. NATURE
- Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically heterogeneous mouse model of T-cell acute lymphoblastic leukemia
- (2019) Jie Gao et al. Disease Models & Mechanisms
- Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade
- (2019) Daniel A. Rauch et al. BLOOD
- Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia
- (2018) Nikos Kourtis et al. NATURE MEDICINE
- Rapid Progression of Adult T-Cell Leukemia–Lymphoma after PD-1 Inhibitor Therapy
- (2018) Lee Ratner et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis
- (2017) Tim Wartewig et al. NATURE
- Acute lymphoblastic leukemia: a comprehensive review and 2017 update
- (2017) T Terwilliger et al. Blood Cancer Journal
- High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival
- (2016) Daniel T. Utzschneider et al. JOURNAL OF EXPERIMENTAL MEDICINE
- T-Cell Lymphoma: Recent Advances in Characterization and New Opportunities for Treatment
- (2016) Carla Casulo et al. JNCI-Journal of the National Cancer Institute
- Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
- (2016) K. E. Pauken et al. SCIENCE
- Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia
- (2016) A. Trinquand et al. Cancer Discovery
- T-Cell Lymphoma: Recent Advances in Characterization and New Opportunities for Treatment
- (2016) Carla Casulo et al. JNCI-Journal of the National Cancer Institute
- A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia
- (2014) Daniel Herranz et al. NATURE MEDICINE
- Immune Modulation in Cancer with Antibodies
- (2013) David B. Page et al. Annual Review of Medicine
- The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability
- (2013) Bryan King et al. CELL
- c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
- (2012) Zuqin Nie et al. CELL
- Notch signaling regulates PD-1 expression during CD8+ T-cell activation
- (2012) Mélissa Mathieu et al. IMMUNOLOGY AND CELL BIOLOGY
- The molecular basis of T cell acute lymphoblastic leukemia
- (2012) Pieter Van Vlierberghe et al. JOURNAL OF CLINICAL INVESTIGATION
- NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species
- (2012) Vincenzo Giambra et al. NATURE MEDICINE
- Stem cell gene expression programs influence clinical outcome in human leukemia
- (2011) Kolja Eppert et al. NATURE MEDICINE
- Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance
- (2010) P. P. L. Chiu et al. BLOOD
- TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells
- (2010) Yoshikane Kikushige et al. Cell Stem Cell
- The Lmo2 Oncogene Initiates Leukemia in Mice by Inducing Thymocyte Self-Renewal
- (2010) M. P. McCormack et al. SCIENCE
- Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
- (2009) T. Sanda et al. BLOOD
- Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss
- (2009) H. Medyouf et al. BLOOD
- PD-1 and Its Ligands in Tolerance and Immunity
- (2008) Mary E. Keir et al. Annual Review of Immunology
- NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity
- (2008) F. Armstrong et al. BLOOD
- Acute lymphoblastic leukaemia
- (2008) Ching-Hon Pui et al. LANCET
- Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation
- (2008) Wei Guo et al. NATURE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started