Synthesis and Molecular Docking of Some Novel 3-Thiazolyl-Coumarins as Inhibitors of VEGFR-2 Kinase

Three-Component Synthesis of Some New Coumarin Derivatives as Anticancer Agents

(2022) Latifah A. Alshabanah et al.   Frontiers in Chemistry

New pyrimidine/thiazole hybrids endowed with analgesic, anti‐inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX‐2/sEH dual inhibition

(2022) Salah A. Abdel‐Aziz et al.   ARCHIV DER PHARMAZIE

Novel Pyridinium Based Ionic Liquid Promoter for Aqueous Knoevenagel Condensation: Green and Efficient Synthesis of New Derivatives with Their Anticancer Evaluation

(2022) AbdElAziz A. Nayl et al.   MOLECULES

Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents

(2022) Mohammed F. Arshad et al.   MOLECULES

Synthesis, Molecular Docking Study, and Cytotoxic Activity against MCF Cells of New Thiazole–Thiophene Scaffolds

(2022) Sobhi M. Gomha et al.   MOLECULES

Synthesis, Molecular Docking Study, and Cytotoxicity Evaluation of Some Novel 1,3,4-Thiadiazole as Well as 1,3-Thiazole Derivatives Bearing a Pyridine Moiety

(2022) Amr S. Abouzied et al.   MOLECULES

Novel thiadiazole-thiazole hybrids: synthesis, molecular docking, and cytotoxicity evaluation against liver cancer cell lines

(2022) Ghadah F. Aljohani et al.   Journal of Taibah University for Science

Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study

(2021) Sobhi M Gomha et al.   Drug Design Development and Therapy

Novel 4-(piperazin-1-yl)quinolin-2(1H)-one bearing thiazoles with antiproliferative activity through VEGFR-2-TK inhibition

(2021) Abdelfattah Hassan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies

(2021) Ismail M.M. Othman et al.   BIOORGANIC CHEMISTRY

Synthesis and characterization of novel thiazole derivatives as potential anticancer agents: Molecular docking and DFT studies

(2021) R. Raveesha et al.   Computational Toxicology

Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway

(2020) Shahad W. Kattan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer

(2019) Mohamed A. Tantawy et al.   Anti-Cancer Agents in Medicinal Chemistry

Screening of different drug design tools to predict the mode of action of steroidal derivatives as anti-cancer agents

(2019) Mohamed S. Nafie et al.   STEROIDS

Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells

(2018) Rasha Z. Batran et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, Synthesis, and Evaluation of a New Series of Thiazole-Based Anticancer Agents as Potent Akt Inhibitors

(2018) Mehlika Altıntop et al.   MOLECULES

5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

(2018) Sobhi Gomha et al.   Drug Design Development and Therapy

Eco-Friendly Synthesis, Characterization and Biological Evaluation of Some Novel Pyrazolines Containing Thiazole Moiety as Potential Anticancer and Antimicrobial Agents

(2018) Mastoura Edrees et al.   MOLECULES

Novel SERMs based on 3-aryl-4-aryloxy-2H-chromen-2-one skeleton - A possible way to dual ERα/VEGFR-2 ligands for treatment of breast cancer

(2017) Guoshun Luo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of piperazine-based thiazolidinones as VEGFR2 tyrosine kinase inhibitors inducing apoptosis

(2017) Mostafa MM El-Miligy et al.   Future Medicinal Chemistry

Esculetin Inhibits VEGF-Induced Angiogenesis Both In Vitro and In Vivo

(2016) Sung Lyea Park et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

1-Piperazinylphthalazines as potential VEGFR-2 inhibitors and anticancer agents: Synthesis and in vitro biological evaluation

(2016) Sahar M. Abou-Seri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cinnamoyloxy-mammeisin Isolated from Geopropolis Attenuates Inflammatory Process by Inhibiting Cytokine Production: Involvement of MAPK, AP-1, and NF-κB

(2016) Marcelo Franchin et al.   JOURNAL OF NATURAL PRODUCTS

Synthesis and antioxidant properties of novel 2H-chromene-3-carboxylate and 3-acetyl-2H-chromene derivatives

(2016) Paramasivam Sivaguru et al.   TETRAHEDRON LETTERS

Synthesis and Antitumor Activity of 1,3,4-Thiadiazole Derivatives Bearing Coumarine Ring

(2015) Sobhi M. Gomha et al.   HETEROCYCLES

Synthesis and Anticancer Activities of Thiazoles, 1,3-Thiazines, and Thiazolidine Using Chitosan-Grafted-Poly(vinylpyridine) as Basic Catalyst

(2015) Sayed M. Riyadh et al.   HETEROCYCLES

Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity

(2015) Rita Morigi et al.   Recent Patents on Anti-Cancer Drug Discovery

SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation

(2015) Peng Zhao et al.   BMC CANCER

Implementation of the National Breast and Cervical Cancer Early Detection Program: The beginning

(2014) Nancy C. Lee et al.   CANCER

Autocrine functions of VEGF in breast tumor cells

(2013) Martine Perrot-Applanat et al.   Cell Adhesion & Migration

Synthesis of New 7-Oxycoumarin Derivatives As Potent and Selective Monoamine Oxidase A Inhibitors

(2012) Omaima M. Abdelhafez et al.   JOURNAL OF MEDICINAL CHEMISTRY

3-Amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5-dihydro-3H-chromeno [2,3-d ]pyrimidine: An Effecient Key Precursor for Novel Synthesis of Some Interesting Triazines and Triazepines as Potential Anti-Tumor Agents

(2012) Mohamed G. Badrey et al.   MOLECULES

A Convenient Ultrasound-Promoted Synthesis of Some New Thiazole Derivatives Bearing a Coumarin Nucleus and Their Cytotoxic Activity

(2012) Sobhi M. Gomha et al.   MOLECULES

Role of VEGF/VEGFR in the pathogenesis of leukemias and as treatment targets (Review)

(2012) GUANHUA SONG et al.   ONCOLOGY REPORTS

Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors

(2012) M. McTigue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental treatment of oestrogen receptor (ER) positive breast cancer with tamoxifen and brivanib alaninate, a VEGFR-2/FGFR-1 kinase inhibitor: A potential clinical application of angiogenesis inhibitors

(2010) Roshani R. Patel et al.   EUROPEAN JOURNAL OF CANCER

Inhibition of vascular endothelial growth factor-induced angiogenesis by scopoletin through interrupting the autophosphorylation of VEGF receptor 2 and its downstream signaling pathways

(2010) Rong Pan et al.   VASCULAR PHARMACOLOGY

Through the “Gatekeeper Door”: Exploiting the Active Kinase Conformation

(2009) Fabio Zuccotto et al.   JOURNAL OF MEDICINAL CHEMISTRY

VEGF receptor protein–tyrosine kinases: Structure and regulation

(2008) Robert Roskoski   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A facile one-pot synthesis of 6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-ones

(2008) Sobhi M. Gomha   MONATSHEFTE FUR CHEMIE

Protonate3D: Assignment of ionization states and hydrogen coordinates to macromolecular structures

(2008) Paul Labute   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS