Synthesis, Molecular Docking Study, and Cytotoxicity Evaluation of Some Novel 1,3,4-Thiadiazole as Well as 1,3-Thiazole Derivatives Bearing a Pyridine Moiety

Three-Component Synthesis of Some New Coumarin Derivatives as Anticancer Agents

(2022) Latifah A. Alshabanah et al.   Frontiers in Chemistry

Novel Pyridinium Based Ionic Liquid Promoter for Aqueous Knoevenagel Condensation: Green and Efficient Synthesis of New Derivatives with Their Anticancer Evaluation

(2022) AbdElAziz A. Nayl et al.   MOLECULES

Design, Synthesis, Antibacterial Evaluations and In Silico Studies of Novel Thiosemicarbazides and 1,3,4-Thiadiazoles

(2022) Sara Janowska et al.   MOLECULES

Thiazoles: A Retrospective Study on Synthesis, Structure-activity Relationship and Therapeutic Significance

(2022) Shivkant Sharma et al.   Indian Journal of Pharmaceutical Education and Research

Discovery of New 3,3-Diethylazetidine-2,4-dione Based Thiazoles as Nanomolar Human Neutrophil Elastase Inhibitors with Broad-Spectrum Antiproliferative Activity

(2022) Beata Donarska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synthesis and Antimicrobial Activity Screening of Piperazines Bearing N,N′-Bis(1,3,4-thiadiazole) Moiety as Probable Enoyl-ACP Reductase Inhibitors

(2022) Alaa Z. Omar et al.   MOLECULES

Synthesis, Molecular Docking Study, and Cytotoxic Activity against MCF Cells of New Thiazole–Thiophene Scaffolds

(2022) Sobhi M. Gomha et al.   MOLECULES

Synthesis and greener pastures biological study of bis-thiadiazoles as potential Covid-19 drug candidates

(2022) Musa A. Said et al.   Arabian Journal of Chemistry

Concept of Hybrid Drugs and Recent Advancements in Anticancer Hybrids

(2022) Ankit Kumar Singh et al.   Pharmaceuticals

Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study

(2021) Sobhi M Gomha et al.   Drug Design Development and Therapy

L-proline catalyzed green synthesis and anticancer evaluation of novel bioactive benzil bis-hydrazones under grinding technique

(2021) Abdelwahed R. Sayed et al.   Green Chemistry Letters and Reviews

Revisiting Activity of Some Nocodazole Analogues as a Potential Anticancer Drugs Using Molecular Docking and DFT Calculations

(2021) Muhammad Khattab et al.   Frontiers in Chemistry

From triazolophthalazines to triazoloquinazolines: A bioisosterism-guided approach toward the identification of novel PCAF inhibitors with potential anticancer activity

(2021) Mohamed H. El-Shershaby et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, Molecular Docking Analysis and Biological Evaluations of Saccharide-Modified Thiadiazole Sulfonamide Derivatives

(2021) Zuo-Peng Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Proteome Based Approach Defines Candidates for Designing a Multitope Vaccine against the Nipah Virus

(2021) Mohamed A. Soltan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies

(2021) Chao Ma et al.   Frontiers in Chemistry

In Silico Prediction of a Multitope Vaccine against Moraxella catarrhalis: Reverse Vaccinology and Immunoinformatics

(2021) Mohamed A. Soltan et al.   Vaccines

Green synthesis, molecular docking and anticancer activity of novel 1,4-dihydropyridine-3,5-Dicarbohydrazones under grind-stone chemistry

(2020) Sobhi M. Gomha et al.   Green Chemistry Letters and Reviews

Design and discovery of new 1,2,4‐triazolo[4,3‐ c ]quinazolines as potential DNA intercalators and topoisomerase II inhibitors

(2020) Mohamed S. Alesawy et al.   ARCHIV DER PHARMAZIE

Synthesis and Biological Evaluation of Some Novel Thiazole-Based Heterocycles as Potential Anticancer and Antimicrobial Agents

(2019) Sraa Abu-Melha et al.   MOLECULES

5-Arylidene(chromenyl-methylene)-thiazolidinediones: Potential New Agents against Mutant Oncoproteins K-Ras, N-Ras and B-Raf in Colorectal Cancer and Melanoma

(2019) Cristina Nastasă et al.   Medicina-Lithuania

Antibacterial Evaluation and Virtual Screening of New Thiazolyl-Triazole Schiff Bases as Potential DNA-Gyrase Inhibitors

(2018) Cristina Nastasă et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

One-Pot Synthesis of New Thiadiazolyl-Pyridines as Anticancer and Antioxidant Agents

(2018) Sobhi M. Gomha et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Facile Synthesis of Pyrazolo[3,4-c ]pyrazoles Bearing Coumarine Ring as Anticancer Agents

(2018) Sobhi M. Gomha et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Thiazole: A Privileged Motif in Marine Natural Products

(2018) Sunil Kumar et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Novel one-pot expeditious synthesis of 2,4-disubstituted thiazoles through a three-component reaction under solvent free conditions

(2018) Kodam Sujatha et al.   SYNTHETIC COMMUNICATIONS

5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

(2018) Sobhi Gomha et al.   Drug Design Development and Therapy

A Review on Recent Synthetic Strategies and Pharmacological Importance of 1,3-Thiazole Derivatives

(2018) Swarna Gowri et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Eco-Friendly Synthesis, Characterization and Biological Evaluation of Some Novel Pyrazolines Containing Thiazole Moiety as Potential Anticancer and Antimicrobial Agents

(2018) Mastoura Edrees et al.   MOLECULES

Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2,3-thiazole derivatives

(2017) Thiago David dos Santos Silva et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Synthesis and evaluation of some novel thiazoles and 1,3-thiazines as potent agents against the rabies virus

(2016) Magda ABDALLA et al.   TURKISH JOURNAL OF CHEMISTRY

Synthesis and anticancer activity of arylazothiazoles and 1,3,4-thiadiazoles using chitosan-grafted-poly(4-vinylpyridine) as a novel copolymer basic catalyst

(2015) Sobhi M. Gomha et al.   Chemistry of Heterocyclic Compounds

Synthesis and biological evaluation of new pyridines containing imidazole moiety as antimicrobial and anticancer agents

(2015) Ikhlass ABBAS et al.   TURKISH JOURNAL OF CHEMISTRY

Synthesis, characterization, and pharmacological evaluation of some novel thiadiazoles and thiazoles incorporating pyrazole moiety as anticancer agents

(2014) Sobhi M. Gomha et al.   MONATSHEFTE FUR CHEMIE

Design and synthesis of novel pyrimido[4,5- b ]azepine derivatives as HER2/EGFR dual inhibitors

(2013) Youichi Kawakita et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A Convenient Ultrasound-Promoted Synthesis of Some New Thiazole Derivatives Bearing a Coumarin Nucleus and Their Cytotoxic Activity

(2012) Sobhi M. Gomha et al.   MOLECULES

Synthesis, Topoisomerase I and II Inhibitory Activity, Cytotoxicity, and Structure-activity Relationship Study of Rigid Analogues of 2,4,6-Trisubstituted Pyridine Containing 5,6-Dihydrobenzo[h]quinoline Moiety

(2011) Byeong-Seon Jeong et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Synthesis and anti-microbial activity of some 1- substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives

(2011) Rizk E. Khidre et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

(2011) J. Jean Cui et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship

(2010) Pritam Thapa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and anticancer activity of 5-(3-indolyl)-1,3,4-thiadiazoles

(2010) Dalip Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antitumor activity of (4-hydroxyphenyl)[5-substituted alkyl/aryl)-2-thioxo-1,3,4-thiadiazol-3-yl]methanone and [(3,4-disubstituted)-1,3-thiazol-2ylidene]-4-hydroxybenzohydrazide

(2010) Ritesh P. Bhole et al.   MEDICINAL CHEMISTRY RESEARCH

2-Thienyl-4-furyl-6-aryl pyridine derivatives: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study

(2009) Pritam Thapa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities

(2007) Jong-Keun Son et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY