DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody

Nanobody Paratope Ensembles in Solution Characterized by MD Simulations and NMR

(2022) Monica L. Fernández-Quintero et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ColabFold: making protein folding accessible to all

(2022) Milot Mirdita et al.   NATURE METHODS

Amino Acid Composition in Various Types of Nucleic Acid-Binding Proteins

(2021) Martin Bartas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ligand-induced native G-quadruplex stabilization impairs transcription initiation

(2021) Conghui Li et al.   GENOME RESEARCH

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Chemical profiling of DNA G-quadruplex-interacting proteins in live cells

(2021) Xiaoyun Zhang et al.   Nature Chemistry

Structural Biology in the Clouds: The WeNMR-EOSC Ecosystem

(2021) Rodrigo V. Honorato et al.   Frontiers in Molecular Biosciences

Positive charge in the complementarity-determining regions of synthetic nanobody prevents aggregation

(2021) Zhenwei Zhong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

gmx_MMPBSA: A New Tool to Perform End-State Free Energy Calculations with GROMACS

(2021) Mario S. Valdés-Tresanco et al.   Journal of Chemical Theory and Computation

Genome-wide mapping of G-quadruplex structures with CUT&Tag

(2021) Jing Lyu et al.   NUCLEIC ACIDS RESEARCH

Single-cell mapping of DNA G-quadruplex structures in human cancer cells

(2021) Winnie W. I. Hui et al.   Scientific Reports

The regulation and functions of DNA and RNA G-quadruplexes

(2020) Dhaval Varshney et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

(2020) Wei Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Generation and design of nanobodies

(2020) Serge Muyldermans   FEBS Journal

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma

(2019) Yuxiang Wang et al.   Nature Communications

Mammalian CST averts replication failure by preventing G-quadruplex accumulation

(2019) Miaomiao Zhang et al.   NUCLEIC ACIDS RESEARCH

Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing

(2018) Robert Hänsel-Hertsch et al.   Nature Protocols

Global profiling of protein–DNA and protein–nucleosome binding affinities using quantitative mass spectrometry

(2018) Matthew M. Makowski et al.   Nature Communications

Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene

(2018) Sascha Stump et al.   PLoS One

Single domain antibodies for the knockdown of cytosolic and nuclear proteins

(2017) Thomas Böldicke   PROTEIN SCIENCE

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

(2016) G.C.P. van Zundert et al.   JOURNAL OF MOLECULAR BIOLOGY

G-quadruplex structures mark human regulatory chromatin

(2016) Robert Hänsel-Hertsch et al.   NATURE GENETICS

NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies

(2016) Sandrine Moutel et al.   eLife

PyEMMA 2: A Software Package for Estimation, Validation, and Analysis of Markov Models

(2015) Martin K. Scherer et al.   Journal of Chemical Theory and Computation

High-throughput sequencing of DNA G-quadruplex structures in the human genome

(2015) Vicki S Chambers et al.   NATURE BIOTECHNOLOGY

Telomeric G-quadruplexes are a substrate and site of localization for human telomerase

(2015) Aaron L. Moye et al.   Nature Communications

Elevated Levels of G-Quadruplex Formation in Human Stomach and Liver Cancer Tissues

(2014) Giulia Biffi et al.   PLoS One

Defining the RGG/RG Motif

(2013) Palaniraja Thandapani et al.   MOLECULAR CELL

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Thermodynamic Stability and Folding Kinetics of the Major G-Quadruplex and Its Loop Isomers Formed in the Nuclease Hypersensitive Element in the Human c-Myc Promoter: Effect of Loops and Flanking Segments on the Stability of Parallel-Stranded Intramolecular G-Quadruplexes

(2010) Emmanuel Hatzakis et al.   BIOCHEMISTRY

Structure and Properties of a Complex of α-Synuclein and a Single-Domain Camelid Antibody

(2010) Erwin J. De Genst et al.   JOURNAL OF MOLECULAR BIOLOGY