Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice

Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

(2022) Danyang He et al.   IMMUNITY

Distinct functional developments of surviving and eliminated presynaptic terminals

(2021) Mitsuharu Midorikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploiting dynamic enhancer landscapes to decode macrophage and microglia phenotypes in health and disease

(2021) Ty D. Troutman et al.   MOLECULAR CELL

Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS

(2021) Travis E. Faust et al.   NATURE REVIEWS NEUROSCIENCE

Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures

(2020) Vincenzo Crunelli et al.   BRAIN

IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease

(2020) Shun-Fat Lau et al.   Cell Reports

Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

(2020) Phi T. Nguyen et al.   CELL

A new genetic strategy for targeting microglia in development and disease

(2020) Gabriel L McKinsey et al.   eLife

Pioneer Transcription Factors Initiating Gene Network Changes

(2020) Kenneth S. Zaret   Annual Review of Genetics

Temporal evolution of cortical ensembles promoting remote memory retrieval

(2019) Laura A. DeNardo et al.   NATURE NEUROSCIENCE

Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models

(2019) Michelle W. Antoine et al.   NEURON

Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet Syndrome

(2019) Stefanie Ritter-Makinson et al.   Cell Reports

Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders

(2019) Vikaas S. Sohal et al.   MOLECULAR PSYCHIATRY

The immune system and psychiatric disease: a basic science perspective

(2019) F. C. Bennett et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells

(2019) Keiro Shirotani et al.   Scientific Reports

Fast, sensitive and accurate integration of single-cell data with Harmony

(2019) Ilya Korsunsky et al.   NATURE METHODS

Brain cell type–specific enhancer–promoter interactome maps and disease-risk association

(2019) Alexi Nott et al.   SCIENCE

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

(2018) Fabia Filipello et al.   IMMUNITY

Epigenetic regulation of brain region-specific microglia clearance activity

(2018) Pinar Ayata et al.   NATURE NEUROSCIENCE

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development

(2018) Ilia D. Vainchtein et al.   SCIENCE

Hijacking of the AP-1 Signaling Pathway during Development of ATL

(2018) Hélène Gazon et al.   Frontiers in Microbiology

Transcriptional control of microglia phenotypes in health and disease

(2017) Inge R. Holtman et al.   JOURNAL OF CLINICAL INVESTIGATION

Scavenger Receptor MARCO Orchestrates Early Defenses and Contributes to Fungal Containment during Cryptococcal Infection

(2017) Jintao Xu et al.   JOURNAL OF IMMUNOLOGY

Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex

(2017) Sinisa Hrvatin et al.   NATURE NEUROSCIENCE

Bidirectional Control of Generalized Epilepsy Networks via Rapid Real-Time Switching of Firing Mode

(2017) Jordan M. Sorokin et al.   NEURON

Microglia in CNS development: Shaping the brain for the future

(2017) Coralie-Anne Mosser et al.   PROGRESS IN NEUROBIOLOGY

An environment-dependent transcriptional network specifies human microglia identity

(2017) David Gosselin et al.   SCIENCE

variancePartition: interpreting drivers of variation in complex gene expression studies

(2016) Gabriel E. Hoffman et al.   BMC BIOINFORMATICS

Electrical synapses and the development of inhibitory circuits in the thalamus

(2016) Timothy A. Zolnik et al.   JOURNAL OF PHYSIOLOGY-LONDON

TAM receptors regulate multiple features of microglial physiology

(2016) Lawrence Fourgeaud et al.   NATURE

Microglia: Architects of the Developing Nervous System

(2016) Jeffrey L. Frost et al.   TRENDS IN CELL BIOLOGY

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Immunity and Inflammation in Epilepsy

(2015) Annamaria Vezzani et al.   Cold Spring Harbor Perspectives in Medicine

Dynamics of networks during absence seizure's on- and offset in rodents and man

(2015) Annika Lüttjohann et al.   Frontiers in Physiology

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

(2014) David Gosselin et al.   CELL

Large-Scale Somatotopic Refinement via Functional Synapse Elimination in the Sensory Thalamus of Developing Mice

(2014) Y. Takeuchi et al.   JOURNAL OF NEUROSCIENCE

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity

(2014) Anna V. Molofsky et al.   NATURE

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

(2012) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes

(2011) J. W. Rowley et al.   BLOOD

Return to homeostasis: downregulation of NF-κB responses

(2011) Jürgen Ruland   NATURE IMMUNOLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number

(2010) Dominic M. Ippolito et al.   Jove-Journal of Visualized Experiments

ATF3 transcription factor and its emerging roles in immunity and cancer

(2009) Matthew R. Thompson et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Cortical activity regulates corticothalamic synapses in dorsal lateral geniculate nucleus of rats

(2009) Miho Yoshida et al.   NEUROSCIENCE RESEARCH

A revised Racine's scale for PTZ-induced seizures in rats

(2009) Annika Lüttjohann et al.   PHYSIOLOGY & BEHAVIOR

Conserved domains of the class A scavenger receptors: evolution and function

(2008) Dawn M. E. Bowdish et al.   IMMUNOLOGICAL REVIEWS