Phase I Metabolism of Pterostilbene, a Dietary Resveratrol Derivative: Metabolite Identification, Species Differences, Isozyme Contribution, and Further Bioactivation
出版年份 2022 全文链接
标题
Phase I Metabolism of Pterostilbene, a Dietary Resveratrol Derivative: Metabolite Identification, Species Differences, Isozyme Contribution, and Further Bioactivation
作者
关键词
-
出版物
Journal of Agricultural and Food Chemistry
Volume 71, Issue 1, Pages 331-346
出版商
American Chemical Society (ACS)
发表日期
2022-12-21
DOI
10.1021/acs.jafc.2c05334
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Subacute oral toxicology and toxicokinetics of pterostilbene, a novel Top1/Tdp1 inhibiting anti-tumor reagent
- (2022) Changcheng Sun et al. DRUG AND CHEMICAL TOXICOLOGY
- High‐resolution mass spectrometry‐based methodology for the identification of the metabolites of pterostilbene produced by rat, dog and human hepatocytes
- (2021) Lingyan Jiang et al. BIOMEDICAL CHROMATOGRAPHY
- Pterostilbene in Cancer Therapy
- (2021) Elena Obrador et al. Antioxidants
- Gastrointestinal biotransformation and tissue distribution of pterostilbene after long-term dietary administration in mice
- (2021) Yue Sun et al. FOOD CHEMISTRY
- Effect of Pterostilbene, a Natural Derivative of Resveratrol, in the Treatment of Colorectal Cancer through Top1/Tdp1-Mediated DNA Repair Pathway
- (2021) Yutian Zhang et al. Cancers
- Oxidative Transformations of 3,4-Dihydroxyphenylacetaldehyde Generate Potential Reactive Intermediates as Causative Agents for Its Neurotoxicity
- (2021) Shosuke Ito et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pterostilbene: mechanisms of its action as oncostatic agent in cell models and in vivo studies
- (2019) Zhiqiang Ma et al. PHARMACOLOGICAL RESEARCH
- Pterostilbene Reduces Liver Steatosis and Modifies Hepatic Fatty Acid Profile in Obese Rats
- (2019) Hijona et al. Nutrients
- Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids
- (2019) Veronika Leláková et al. FOOD CHEMISTRY
- Anti-tumor properties of methoxylated analogues of resveratrol in malignant MCF-7 but not in non-tumorigenic MCF-10A mammary epithelial cell lines
- (2019) Annick D. van den Brand et al. TOXICOLOGY
- Antioxidant Activity of Selected Stilbenoid Derivatives in a Cellular Model System
- (2019) Treml et al. Biomolecules
- Effects of pterostilbene on diabetes, liver steatosis and serum lipids
- (2019) Saioa Gómez-Zorita et al. CURRENT MEDICINAL CHEMISTRY
- Metabolism and pharmacokinetics of resveratrol and pterostilbene
- (2018) Pei Wang et al. BIOFACTORS
- Pterostilbene modulates the suppression of multidrug resistance protein�1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling
- (2018) Hui-Ping Chang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Resveratrol and pinostilbene confer neuroprotection against aging-related deficits through an ERK1/2-dependent mechanism
- (2018) Erika N. Allen et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity
- (2017) Yogesh C. Awasthi et al. FREE RADICAL BIOLOGY AND MEDICINE
- Biological actions and molecular effects of resveratrol, pterostilbene, and 3′-hydroxypterostilbene
- (2017) Hui-Yun Tsai et al. JOURNAL OF FOOD AND DRUG ANALYSIS
- Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: Possible implications for susceptibility to amodiaquine-induced liver toxicity
- (2017) Yongjie Zhang et al. TOXICOLOGY LETTERS
- Evaluation of 90 day repeated dose oral toxicity and reproductive/developmental toxicity of 3'-hydroxypterostilbene in experimental animals
- (2017) Muhammed Majeed et al. PLoS One
- Different Reactive Metabolites of Nevirapine Require Distinct Glutathione S-Transferase Isoforms for Bioinactivation
- (2016) Stefan J. Dekker et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Pterostilbene exerts an anti-inflammatory effect via regulating endoplasmic reticulum stress in endothelial cells
- (2016) Jun Liu et al. CYTOKINE
- Determination of pinostilbene in rat plasma by LC–MS/MS: Application to a pharmacokinetic study
- (2016) Wan Chen et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Identification of pinostilbene as a major colonic metabolite of pterostilbene and its inhibitory effects on colon cancer cells
- (2016) Yue Sun et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Pterostilbene induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma cells
- (2016) Yuanyuan Kong et al. Scientific Reports
- Urokinase-type plasminogen activator expression and Rac1/WAVE-2/Arp2/3 pathway are blocked by pterostilbene to suppress cell migration and invasion in MDA-MB-231 cells
- (2014) Hyun Suk Ko et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Pterostilbene, a Dimethyl Ether Derivative of Resveratrol, Reduces Fat Accumulation in Rats Fed an Obesogenic Diet
- (2014) Saioa Gómez-Zorita et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Pharmacokinetics and tissue distribution of pterostilbene in the rat
- (2014) Michele Azzolini et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Differences in the Glucuronidation of Resveratrol and Pterostilbene: Altered Enzyme Specificity and Potential Gender Differences
- (2013) Ryan W. Dellinger et al. Drug Metabolism and Pharmacokinetics
- Bioactivation of Drugs: Risk and Drug Design
- (2011) John S. Walsh et al. Annual Review of Pharmacology and Toxicology
- Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors
- (2011) H. K. Crewe et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- Involvement of Different Human Glutathione Transferase Isoforms in the Glutathione Conjugation of Reactive Metabolites of Troglitazone
- (2011) R. Okada et al. DRUG METABOLISM AND DISPOSITION
- Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity
- (2011) Siamak Cyrus Khojasteh et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Structural identification of mouse urinary metabolites of pterostilbene using liquid chromatography/tandem mass spectrometry
- (2010) Xi Shao et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Pharmacometrics of pterostilbene: preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity
- (2007) Connie M. Remsberg et al. PHYTOTHERAPY RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now