Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage

CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes

(2021) Yiangos Psaras et al.   CIRCULATION RESEARCH

Unfolded protein response during cardiovascular disorders: a tilt towards pro-survival and cellular homeostasis

(2021) Shreya Das et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

(2021) Colin W. Garvie et al.   Nature Communications

AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR

(2021) Cathrine R. Carlson et al.   CIRCULATION RESEARCH

Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia

(2021) Nadja I. Bork et al.   Redox Biology

Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure

(2020) Sarah Karam et al.   CIRCULATION

Phosphodiesterase 3A and Arterial Hypertension

(2020) Maria Ercu et al.   CIRCULATION

Cells of the adult human heart

(2020) Monika Litviňuková et al.   NATURE

Identification and functional study of genetic polymorphisms in cyclic nucleotide phosphodiesterase 3A ( PDE3A )

(2020) You Ran Kim et al.   ANNALS OF HUMAN GENETICS

Fluconazole Increases Osmotic Water Transport in Renal Collecting Duct through Effects on Aquaporin-2 Trafficking

(2019) Tanja Vukićević et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases

(2019) Faisa Omar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

PDE3A gene screening improves diagnostics for patients with Bilginturan syndrome (hypertension and brachydactyly syndrome)

(2018) Kirsten Y. Renkema et al.   HYPERTENSION RESEARCH

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial InfarctionNovelty and Significance

(2016) Christiane Vettel et al.   CIRCULATION RESEARCH

The Case| A handful of hypertension

(2016) Bert-Jan H. van den Born et al.   KIDNEY INTERNATIONAL

A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension

(2016) Michael H Olsen et al.   LANCET

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

(2016) Christopher D Richardson et al.   NATURE BIOTECHNOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Clinical Effects of Phosphodiesterase 3A Mutations in Inherited Hypertension With BrachydactylyNovelty and Significance

(2015) Okan Toka et al.   HYPERTENSION

Regulation of Sarcoplasmic Reticulum Ca2+ATPase 2 (SERCA2) Activity by Phosphodiesterase 3A (PDE3A) in Human Myocardium

(2015) Faiyaz Ahmad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PDE3A mutations cause autosomal dominant hypertension with brachydactyly

(2015) Philipp G Maass et al.   NATURE GENETICS

Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury

(2015) Youn Wook Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphodiesterase 3A1 Protects the Heart Against Angiotensin II–induced Cardiac Remodeling Through Regulation of Transforming Growth Factor-β Expression

(2014) Shoji Iwaya et al.   International Heart Journal

Nebivolol prevents desensitization of β-adrenoceptor signaling and induction of cardiac hypertrophy in response to isoprenaline beyond β1-adrenoceptor blockage

(2013) Isil Ozakca et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury

(2013) Masayoshi Oikawa et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Seamless genome editing in human pluripotent stem cells using custom endonuclease–based gene targeting and the piggyBac transposon

(2013) Kosuke Yusa   Nature Protocols

Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms

(2013) F. Vandeput et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-SeQC: RNA-seq metrics for quality control and process optimization

(2012) David S. DeLuca et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS