AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR

The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)

(2019) Sabrina Bech Mathiesen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation

(2019) Katherina M. Alsina et al.   CIRCULATION

The Ras-like GTPase Rem2 is a potent inhibitor of calcium/calmodulin-dependent kinase II activity

(2018) Leandro Royer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac CaMKII activation promotes rapid translocation to its extra-dyadic targets

(2018) Brent M. Wood et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes

(2018) Terje R Kolstad et al.   eLife

Protocol for Efficient Generation and Characterization of Adeno-Associated Viral Vectors

(2017) Andreas Jungmann et al.   Human Gene Therapy Methods

Malonate in the nucleotide-binding site traps human AKAP18γ/δ in a novel conformational state

(2016) Kaare Bjerregaard-Andersen et al.   Acta Crystallographica Section F-Structural Biology Communications

Regulation of Sarcoplasmic Reticulum Ca2+ATPase 2 (SERCA2) Activity by Phosphodiesterase 3A (PDE3A) in Human Myocardium

(2015) Faiyaz Ahmad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-Nitrosylation Induces Both Autonomous Activation and Inhibition of Calcium/Calmodulin-dependent Protein Kinase II δ

(2015) Jeffrey R. Erickson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secretoneurin Is a Novel Prognostic Cardiovascular Biomarker Associated With Cardiomyocyte Calcium Handling

(2015) Anett Hellebø Ottesen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase

(2014) Stanislas Werfel et al.   CARDIOVASCULAR RESEARCH

Nitric Oxide Induces Ca2+-independent Activity of the Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII)

(2014) Steven J. Coultrap et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of CaMKII Activation in the Heart

(2014) Jeffrey R. Erickson   Frontiers in Pharmacology

The role of CaMKII regulation of phospholamban activity in heart disease

(2014) Alicia Mattiazzi et al.   Frontiers in Pharmacology

CaMKIIdelta subtypes: localization and function

(2014) Charles B. B. Gray et al.   Frontiers in Pharmacology

Highly Functionalized Terpyridines as Competitive Inhibitors of AKAP-PKA Interactions

(2013) Gesa Schäfer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

(2013) Jeffrey R. Erickson et al.   NATURE

Mechanism for Targeting the A-kinase Anchoring Protein AKAP18δ to the Membrane

(2012) Andreas Horner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban

(2012) Yiming Wu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Activity-Dependent Subcellular Cotrafficking of the Small GTPase Rem2 and Ca2+/CaM-Dependent Protein Kinase IIα

(2012) Robyn Flynn et al.   PLoS One

Fluorescence Resonance Energy Transfer–Based Sensor Camui Provides New Insight Into Mechanisms of Calcium/Calmodulin-Dependent Protein Kinase II Activation in Intact Cardiomyocytes

(2011) Jeffrey R. Erickson et al.   CIRCULATION RESEARCH

Crossing signals: relationships between β-adrenergic stimulation and CaMKII activation

(2011) Michael Grimm et al.   HEART RHYTHM

Characterization of a Central Ca2+/Calmodulin-dependent Protein Kinase IIα/β Binding Domain in Densin That Selectively Modulates Glutamate Receptor Subunit Phosphorylation

(2011) Yuxia Jiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

(2011) Sebastian Börner et al.   Nature Protocols

The Large Isoforms of A-Kinase Anchoring Protein 18 Mediate the Phosphorylation of Inhibitor-1 by Protein Kinase A and the Inhibition of Protein Phosphatase 1 Activity

(2010) A. Singh et al.   MOLECULAR PHARMACOLOGY

Role of CaMKII  phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure

(2010) A. Kushnir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

(2010) Peter Rellos et al.   PLOS BIOLOGY

Sarcoplasmic reticulum Ca2+ATPase as a therapeutic target for heart failure

(2009) Larissa Lipskaia et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology

(2009) Persoulla Nicolaou et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Calmodulin Mediates Differential Sensitivity of CaMKII and Calcineurin to Local Ca2+ in Cardiac Myocytes

(2008) Jeffrey J. Saucerman et al.   BIOPHYSICAL JOURNAL

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

(2008) Jeffrey R. Erickson et al.   CELL

Phosphomimetic Mutations Increase Phospholamban Oligomerization and Alter the Structure of Its Regulatory Complex

(2008) Zhanjia Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AKAP18 Contains a Phosphoesterase Domain that Binds AMP

(2007) Matthew G. Gold et al.   JOURNAL OF MOLECULAR BIOLOGY