Fluconazole Increases Osmotic Water Transport in Renal Collecting Duct through Effects on Aquaporin-2 Trafficking

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells

(2018) Katharina Schrade et al.   PLoS One

AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus

(2018) Fumiaki Ando et al.   Nature Communications

Systems-level identification of PKA-dependent signaling in epithelial cells

(2017) Kiyoshi Isobe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ILDR1 is important for paracellular water transport and urine concentration mechanism

(2017) Yongfeng Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quercetin Assists Fluconazole to Inhibit Biofilm Formations of Fluconazole-Resistant Candida Albicans in In Vitro and In Vivo Antifungal Managements of Vulvovaginal Candidiasis

(2016) Mei Gao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Simvastatin increases AQP2 urinary excretion in hypercholesterolemic patients: A pleiotropic effect of interest for patients with impaired AQP2 trafficking

(2016) G Procino et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption

(2016) P. W. Cheung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Integrated therapy for HIV and cryptococcosis

(2016) Sirawat Srichatrapimuk et al.   AIDS Research and Therapy

The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells—a Potential Target for Pharmacological Intervention in Cardiovascular Diseases

(2016) Tanja Vukićević et al.   Frontiers in Pharmacology

Sildenafil for the Treatment of Congenital Nephrogenic Diabetes Insipidus

(2015) Farahnak Assadi et al.   AMERICAN JOURNAL OF NEPHROLOGY

Rosiglitazone Promotes AQP2 Plasma Membrane Expression In Renal Cells Via a Ca2+-Dependent/cAMP-Independent Mechanism

(2015) Giuseppe Procino et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effects of fluconazole on the metabolomic profile ofCandida albicans

(2015) Aspasia Katragkou et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Urea minimizes brain complications following rapid correction of chronic hyponatremia compared with vasopressin antagonist or hypertonic saline

(2015) Fabrice Gankam Kengne et al.   KIDNEY INTERNATIONAL

Diabetes Insipidus: Celebrating a Century of Vasopressin Therapy

(2014) Sana Qureshi et al.   ENDOCRINOLOGY

Small-Molecule Screening Identifies Modulators of Aquaporin-2 Trafficking

(2013) J. Bogum et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Culturing Primary Rat Inner Medullary Collecting Duct Cells

(2013) Dörte Faust et al.   Jove-Journal of Visualized Experiments

Effects of CYP3A4 inhibition and induction on the pharmacokinetics and pharmacodynamics of tolvaptan, a non-peptide AVP antagonist in healthy subjects

(2011) Susan E. Shoaf et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac Myocytes

(2010) Frank Christian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Human CYP51 Inhibition by Antifungal Azoles

(2010) Natallia Strushkevich et al.   JOURNAL OF MOLECULAR BIOLOGY

Reciprocal Regulation of Aquaporin-2 Abundance and Degradation by Protein Kinase A and p38-MAP Kinase

(2010) P. I. Nedvetsky et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aquaporins in kidney pathophysiology

(2010) Yumi Noda et al.   Nature Reviews Nephrology

Vasopressin-stimulated Increase in Phosphorylation at Ser269Potentiates Plasma Membrane Retention of Aquaporin-2

(2008) Jason D. Hoffert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute regulation of aquaporin-2 phosphorylation at Ser-264 by vasopressin

(2008) R. A. Fenton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology

(2008) Dennis Brown et al.   TRAFFIC