An End Point-Specific Framework for Read-Across Analog Selection for Human Health Effects

RIFM fragrance ingredient safety assessment, cadinene, CAS Registry Number 29350-73-0

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RIFM fragrance ingredient safety assessment, dihydroisocaryophyllene epoxide, CAS Registry Number 1209-61-6

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RIFM fragrance ingredient safety assessment, 6-nonenenitrile, (Z)- (9CI), CAS Registry Number 80639-54-9

(2021) A.M. Api et al.   FOOD AND CHEMICAL TOXICOLOGY

RIFM fragrance ingredient safety assessment, ethyl 3-methyl-2-oxopentanoate, CAS Registry Number 26516-27-8

(2021) A.M. Api et al.   FOOD AND CHEMICAL TOXICOLOGY

RIFM fragrance ingredient safety assessment, p-mentha-1,4-diene, CAS Registry Number 99-85-4

(2021) A.M. Api et al.   FOOD AND CHEMICAL TOXICOLOGY

A matched molecular pair (MMP) approach for selecting analogs suitable for structure activity relationship (SAR)-based read across

(2021) Cathy C. Lester et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Derivation of the no expected sensitization induction level for dermal quantitative risk assessment of fragrance ingredients using a weight of evidence approach

(2021) Isabelle Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

RIFM fragrance ingredient safety assessment, 1-cyclohexene-1-propanal, 4-(1-methylethyl)-, (4R), CAS Registry Number 1378867-81-2

(2021) A.M. Api et al.   FOOD AND CHEMICAL TOXICOLOGY

Use of alternative test methods in a tiered testing approach to address photoirritation potential of fragrance materials

(2021) Gretchen Ritacco et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Clustering a Chemical Inventory for Safety Assessment of Fragrance Ingredients: Identifying Read-Across Analogs to Address Data Gaps

(2020) Mihir S. Date et al.   CHEMICAL RESEARCH IN TOXICOLOGY

In vitro Alternatives to Acute Inhalation Toxicity Studies in Animal Models—A Perspective

(2020) Dania Movia et al.   Frontiers in Bioengineering and Biotechnology

Fragrance Skin Sensitization Evaluation and Human Testing

(2020) Mihwa Na et al.   Dermatitis

Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materials

(2020) Anne Marie Api et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project

(2019) Sylvia E. Escher et al.   ARCHIVES OF TOXICOLOGY

Molecular fingerprint-derived similarity measures for toxicological read-across: Recommendations for optimal use

(2018) C.L. Mellor et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments

(2017) Satomi Onoue et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Lessons learned from read-across case studies for repeated-dose toxicity

(2017) Terry W. Schultz et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients

(2015) A.M. Api et al.   FOOD AND CHEMICAL TOXICOLOGY

A strategy for structuring and reporting a read-across prediction of toxicity

(2015) T.W. Schultz et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations?

(2015) Dávid Bajusz et al.   Journal of Cheminformatics

Measurement and Estimation of Electrophilic Reactivity for Predictive Toxicology

(2011) Johannes A. H. Schwöbel et al.   CHEMICAL REVIEWS

A review of the electrophilic reaction chemistry involved in covalent protein binding relevant to toxicity

(2011) S. J. Enoch et al.   CRITICAL REVIEWS IN TOXICOLOGY

A review of the electrophilic reaction chemistry involved in covalent DNA binding

(2010) S. J. Enoch et al.   CRITICAL REVIEWS IN TOXICOLOGY

Can light absorption and photostability data be used to assess the photosafety risks in patients for a new drug molecule?

(2009) Brian Henry et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY