Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project

Identification and description of the uncertainty, variability, bias and influence in quantitative structure-activity relationships (QSARs) for toxicity prediction

(2019) Mark T.D. Cronin et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Toxicokinetics in Risk Evaluations

(2018) Ans Punt   CHEMICAL RESEARCH IN TOXICOLOGY

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

(2018) Anna Bal-Price   ALTEX-Alternatives to Animal Experimentation

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

(2018) David Pamies   ALTEX-Alternatives to Animal Experimentation

Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data

(2018) Jin Dong et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Mechanisms, monitoring, and management of tyrosine kinase inhibitors-associated cardiovascular toxicities

(2018) Maher Chaar et al.   OncoTargets and Therapy

VIVD: Virtual in vitro distribution model for the mechanistic prediction of intracellular concentrations of chemicals in in vitro toxicity assays

(2018) C. Fisher et al.   TOXICOLOGY IN VITRO

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework

(2017) Jake Nikota et al.   Particle and Fibre Toxicology

Retrospective mining of toxicology data to discover multispecies and chemical class effects: Anemia as a case study

(2017) Richard S. Judson et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Adverse outcome pathway development from protein alkylation to liver fibrosis

(2016) Tomislav Horvat et al.   ARCHIVES OF TOXICOLOGY

Indoor air guide values for glycol ethers and glycol esters—A category approach

(2016) Inge Mangelsdorf et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Metabolomics as read-across tool: A case study with phenoxy herbicides

(2016) B. van Ravenzwaay et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information

(2016) Imran Shah et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Toward Good Read-Across Practice (GRAP) guidance

(2016) Nicholas Ball   ALTEX-Alternatives to Animal Experimentation

Pharmacometric Models for Characterizing the Pharmacokinetics of Orally Inhaled Drugs

(2015) Jens Markus Borghardt et al.   AAPS Journal

A strategy for structuring and reporting a read-across prediction of toxicity

(2015) T.W. Schultz et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Building scientific confidence in the development and evaluation of read-across

(2015) G. Patlewicz et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Big Data in Chemical Toxicity Research: The Use of High-Throughput Screening Assays To Identify Potential Toxicants

(2014) Hao Zhu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A framework to facilitate consistent characterization of read across uncertainty

(2014) Karen Blackburn et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Adverse Outcome Pathway Development II: Best Practices

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Integrative Chemical–Biological Read-Across Approach for Chemical Hazard Classification

(2013) Yen Low et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Development of an Adverse Outcome Pathway From Drug-Mediated Bile Salt Export Pump Inhibition to Cholestatic Liver Injury

(2013) Mathieu Vinken et al.   TOXICOLOGICAL SCIENCES

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Structure−Activity Landscape Index:  Identifying and Quantifying Activity Cliffs

(2008) Rajarshi Guha et al.   Journal of Chemical Information and Modeling