Andrographolide attenuates LPS-stimulated up-regulation of C-C and C-X-C motif chemokines in rodent cortex and primary astrocytes

Specificity and Inhibitory Mechanism of Andrographolide and Its Analogues as Antiasthma Agents on NF-κB p50

(2015) Van Sang Nguyen et al.   JOURNAL OF NATURAL PRODUCTS

Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines

(2015) Stefka Gyoneva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

CXCL9 and CXCL10 Expression Are Critical for Control of Genital Herpes Simplex Virus Type 2 Infection through Mobilization of HSV-Specific CTL and NK Cells to the Nervous System

(2014) M. Thapa et al.   JOURNAL OF IMMUNOLOGY

Chronic neuroinflammation and cognitive impairment following transient global cerebral ischemia: role of fractalkine/CX3CR1 signaling

(2014) Teresita L Briones et al.   Journal of Neuroinflammation

Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation

(2014) Debayon Paul et al.   Journal of Neuroinflammation

TNFR1-JNK signaling is the shared pathway of neuroinflammation and neurovascular damage after LPS-sensitized hypoxic-ischemic injury in the immature brain

(2014) Lan-Wan Wang et al.   Journal of Neuroinflammation

Andrographolide attenuates interleukin-1β-stimulated upregulation of chemokine CCL5 and glial fibrillary acidic protein in astrocytes

(2014) Siew-Ying Wong et al.   NEUROREPORT

Astrocyte Reactivity and Reactive Astrogliosis: Costs and Benefits

(2014) Milos Pekny et al.   PHYSIOLOGICAL REVIEWS

Review on Liver Inflammation and Antiinflammatory Activity ofAndrographis paniculatafor Hepatoprotection

(2014) Lee Suan Chua   PHYTOTHERAPY RESEARCH

Pharmacokinetic analysis and tissue distribution of andrographolide in rat by a validated LC-MS/MS method

(2013) Rammohan Bera et al.   PHARMACEUTICAL BIOLOGY

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

(2013) Donal T. Skelly et al.   PLoS One

Suppression of NF-κB signaling by andrographolide with a novel mechanism in human platelets: Regulatory roles of the p38 MAPK-hydroxyl radical-ERK2 cascade

(2012) Wan J. Lu et al.   BIOCHEMICAL PHARMACOLOGY

Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity

(2012) SP Guan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chemokines in CNS injury and repair

(2012) Anne Jaerve et al.   CELL AND TISSUE RESEARCH

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Production of TNF-  in Macrophages Activated by T Cells, Compared with Lipopolysaccharide, Uses Distinct IL-10-Dependent Regulatory Mechanism

(2012) G. Agbanoma et al.   JOURNAL OF IMMUNOLOGY

JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain

(2012) Lan-Wan Wang et al.   Journal of Neuroinflammation

Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: Multiplex quantification with path analysis

(2011) Michelle A. Erickson et al.   BRAIN BEHAVIOR AND IMMUNITY

Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer

(2011) Jonathan Chee Woei Lim et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

IKK-β-mediated myeloid cell activation exacerbates inflammation and inhibits recovery after spinal cord injury

(2011) Junghee Kang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NFκB and JNK/MAPK Activation Mediates the Production of Major Macrophage- or Dendritic Cell-Recruiting Chemokine in Human First Trimester Decidual Cells in Response to Proinflammatory Stimuli

(2011) Min Li et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Selective Oestrogen Receptor Modulators Decrease the Inflammatory Response of Glial Cells

(2011) M. A. Arevalo et al.   JOURNAL OF NEUROENDOCRINOLOGY

Effects of andrographolide and 14-deoxy-11,12-didehydroandrographolide on cultured primary astrocytes and PC12 cells

(2011) Yew-Min Tzeng et al.   LIFE SCIENCES

Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells

(2011) Lili Ji et al.   MOLECULAR CARCINOGENESIS

Neuroprotective effects of andrographolide in a rat model of permanent cerebral ischaemia

(2010) Su Jing Chan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian)

(2010) Wen-Wan Chao et al.   Chinese Medicine

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

MAPK Signal Transduction Underlying Brain Inflammation and Gliosis as Therapeutic Target

(2009) Bozena Kaminska et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

N-Tosyl-l-phenylalanine Chloromethyl Ketone Inhibits NF-κB Activation by Blocking Specific Cysteine Residues of IκB Kinase β and p65/RelA

(2009) Kyung-Ho Ha et al.   BIOCHEMISTRY

Activity of Andrographolide and Its Derivatives against Influenza Virus in Vivo and in Vitro

(2009) Jian-Xin Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion

(2009) Isabelle Pineau et al.   BRAIN BEHAVIOR AND IMMUNITY

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial

(2009) R. A. Burgos et al.   CLINICAL RHEUMATOLOGY

Inhibition of CXCR2 signaling promotes recovery in models of multiple sclerosis

(2009) A.E. Kerstetter et al.   EXPERIMENTAL NEUROLOGY

Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-γ-inducible protein-10 by astrocytes exposed to inflammatory challengein vitro

(2009) M. Cerciat et al.   GLIA

The blood–brain barrier and immune function and dysfunction

(2009) William A. Banks et al.   NEUROBIOLOGY OF DISEASE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Role of CX3CR1 (Fractalkine Receptor) in Brain Damage and Inflammation Induced by Focal Cerebral Ischemia in Mouse

(2008) Ádám Dénes et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM