Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age
出版年份 2023 全文链接
标题
Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age
作者
关键词
-
出版物
AGING CELL
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2023-01-14
DOI
10.1111/acel.13767
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction
- (2022) Cara L. Green et al. Cell Metabolism
- A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice
- (2021) Michael A Petr et al. eLife
- Aging Reduces Insulin Clearance in Mice
- (2021) Carine Marmentini et al. Frontiers in Endocrinology
- Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice
- (2020) Matthew J. Yousefzadeh et al. AGING CELL
- Discovery, Development, and Future Application of Senolytics: Theories and Predictions
- (2020) Erin O. Wissler Gerdes et al. FEBS Journal
- The Immune Landscape of Visceral Adipose Tissue During Obesity and Aging
- (2020) Saad Khan et al. Frontiers in Endocrinology
- Transient metabolic improvement in obese mice treated with navitoclax or dasatinib/quercetin
- (2020) Arantzazu Sierra-Ramirez et al. Aging-US
- Lifelong SIRT-1 overexpression attenuates large artery stiffening with advancing age
- (2020) Daniel R. Machin et al. Aging-US
- Senolytic drugs: from discovery to translation
- (2020) J. L. Kirkland et al. JOURNAL OF INTERNAL MEDICINE
- A Senescence-Centric View of Aging: Implications for Longevity and Disease
- (2020) M. Borghesan et al. TRENDS IN CELL BIOLOGY
- Senescence in Wound Repair: Emerging Strategies to Target Chronic Healing Wounds
- (2020) Holly N. Wilkinson et al. Frontiers in Cell and Developmental Biology
- Aging differentially impacts vasodilation and angiogenesis in arteries from the white and brown adipose tissues
- (2020) Md Torikul Islam et al. EXPERIMENTAL GERONTOLOGY
- Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
- (2019) Allyson K. Palmer et al. AGING CELL
- Senescent cell clearance by the immune system: Emerging therapeutic opportunities
- (2019) Larissa G.P. Langhi Prata et al. SEMINARS IN IMMUNOLOGY
- Quercetin Loaded Nanoparticles in Targeting Cancer: Recent Development
- (2019) Manjula Vinayak et al. Anti-Cancer Agents in Medicinal Chemistry
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
- (2019) LaTonya J. Hickson et al. EBioMedicine
- Cellular Senescence: Defining a Path Forward
- (2019) Vassilis Gorgoulis et al. CELL
- Dasatinib-induced pulmonary arterial hypertension
- (2018) Nurgül Özgür Yurttaş et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Mechanisms and functions of cellular senescence
- (2018) Nicolás Herranz et al. JOURNAL OF CLINICAL INVESTIGATION
- Age-Related Changes in Glucose Metabolism, Hyperglycemia, and Cardiovascular Risk
- (2018) Chee W. Chia et al. CIRCULATION RESEARCH
- T Cells in Adipose Tissue in Aging
- (2018) Antu Kalathookunnel Antony et al. Frontiers in Immunology
- Animal models of atherosclerosis
- (2017) Besa Emini Veseli et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Actions of Quercetin, a Polyphenol, on Blood Pressure
- (2017) Yoshinori Marunaka et al. MOLECULES
- Targeting cellular senescence prevents age-related bone loss in mice
- (2017) Joshua N Farr et al. NATURE MEDICINE
- Regulation of hepatic glucose metabolism in health and disease
- (2017) Max C. Petersen et al. Nature Reviews Endocrinology
- Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty
- (2017) Michael B. Stout et al. PHYSIOLOGY
- Age-related arterial immune cell infiltration in mice is attenuated by caloric restriction or voluntary exercise
- (2016) Daniel W. Trott et al. EXPERIMENTAL GERONTOLOGY
- Obesity accelerates T cell senescence in murine visceral adipose tissue
- (2016) Kohsuke Shirakawa et al. JOURNAL OF CLINICAL INVESTIGATION
- Targeting hepatic glucose metabolism in the treatment of type 2 diabetes
- (2016) Amy K. Rines et al. NATURE REVIEWS DRUG DISCOVERY
- Increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice
- (2016) Yoon Sin Oh et al. PLoS One
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Depletion of fat-resident Treg cells prevents age-associated insulin resistance
- (2015) Sagar P. Bapat et al. NATURE
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- (2015) Ming Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting senescent cells enhances adipogenesis and metabolic function in old age
- (2015) Ming Xu et al. eLife
- Metformin improves healthspan and lifespan in mice
- (2013) Alejandro Martin-Montalvo et al. Nature Communications
- Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
- (2009) Markus Feuerer et al. NATURE MEDICINE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started