Caffeine Blocks HIV-1 Tat-Induced Amyloid Beta Production and Tau Phosphorylation

Caffeine Suppresses Amyloid-β Levels in Plasma and Brain of Alzheimer's Disease Transgenic Mice

(2017) Chuanhai Cao et al.   JOURNAL OF ALZHEIMERS DISEASE

Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia: A Population-Based CAIDE Study

(2017) Marjo H. Eskelinen et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer's Disease Mice

(2017) Gary W. Arendash et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine Intake is Associated with a Lower Risk of Cognitive Decline: A Cohort Study from Portugal

(2017) Catarina Santos et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine and Coffee as Therapeutics Against Alzheimer's Disease

(2017) Gary W. Arendash et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine as a Protective Factor in Dementia and Alzheimer's Disease

(2017) Marjo H. Eskelinen et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine Intake and Dementia: Systematic Review and Meta-Analysis

(2017) Catarina Santos et al.   JOURNAL OF ALZHEIMERS DISEASE

APOE ε4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals – a cross-sectional observational study

(2015) Lucette A Cysique et al.   BMC Neurology

Mechanisms of HIV-1 Tat Neurotoxicity via CDK5 Translocation and Hyper-Activation: Role in HIV-Associated Neurocognitive Disorders

(2015) Jerel Fields et al.   CURRENT HIV RESEARCH

Autophagy: An overlooked mechanism of HIV-1 pathogenesis and NeuroAIDS?

(2014) Stephen A. Spector et al.   Autophagy

From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?

(2014) Vanessa Flaten et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB

(2014) V. A. Polito et al.   EMBO Molecular Medicine

Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer’s disease

(2014) A. J. Carman et al.   Journal of Nutrition Health & Aging

Trafficking regulation of proteins in Alzheimer’s disease

(2014) Shangtong Jiang et al.   Molecular Neurodegeneration

Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology

(2014) Cyril Laurent et al.   NEUROBIOLOGY OF AGING

ATP6V0C Knockdown in Neuroblastoma Cells Alters Autophagy-Lysosome Pathway Function and Metabolism of Proteins that Accumulate in Neurodegenerative Disease

(2014) Leandra R. Mangieri et al.   PLoS One

Endolysosome involvement in HIV-1 transactivator protein-induced neuronal amyloid beta production

(2013) Xuesong Chen et al.   NEUROBIOLOGY OF AGING

HIV-1 Tat Interacts with and Regulates the Localization and Processing of Amyloid Precursor Protein

(2013) Jiyoung Kim et al.   PLoS One

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

(2013) T. P. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The lysosome: from waste bag to potential therapeutic target

(2013) Hanna Appelqvist et al.   Journal of Molecular Cell Biology

Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system

(2013) Etienne Morel et al.   Nature Communications

Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease

(2013) Adrianne S. Chesser et al.   Frontiers in Neurology

Cellular and molecular mechanisms of muscle atrophy

(2012) P. Bonaldo et al.   Disease Models & Mechanisms

Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

(2012) Manuel Torres et al.   Molecular Neurodegeneration

Membrane Trafficking Pathways in Alzheimer's Disease

(2012) Lawrence Rajendran et al.   TRAFFIC

Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine

(2011) Christina Patrick et al.   AMERICAN JOURNAL OF PATHOLOGY

Phosphorylation of LRP1 regulates the interaction with Fe65

(2011) Wilfried Klug et al.   FEBS LETTERS

Aβ-Degrading Enzymes: Potential for Treatment of Alzheimer Disease

(2011) James Scott Miners et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

High-Performance Capillary Electrophoresis for Determining HIV-1 Tat Protein in Neurons

(2011) Satish L. Deshmane et al.   PLoS One

ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1

(2011) R. Sannerud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Continued High Prevalence and Adverse Clinical Impact of Human Immunodeficiency Virus–Associated Sensory Neuropathy in the Era of Combination Antiretroviral Therapy

(2010) Ronald J. Ellis   ARCHIVES OF NEUROLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

HIV-1 protein-mediated amyloidogenesis in rat hippocampal cell cultures

(2010) M.Y. Aksenov et al.   NEUROSCIENCE LETTERS

Human immunodeficiency virus type-1 infection inhibits autophagy

(2009) Dejiang Zhou et al.   AIDS

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

HIV Regulation of Amyloid Beta Production

(2009) Lynn Pulliam   Journal of Neuroimmune Pharmacology

Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients

(2009) Cristian L. Achim et al.   Journal of Neuroimmune Pharmacology

CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease

(2009) D. B. Clifford et al.   NEUROLOGY

Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

(2008) Tadanori Hamano et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Comorbidity of HIV-Associated Neurocognitive Disorders and Alzheimer’s Disease: A Foreseeable Medical Challenge in Post-HAART Era

(2008) Jiqing Xu et al.   Journal of Neuroimmune Pharmacology

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

(2008) B. Boland et al.   JOURNAL OF NEUROSCIENCE

Crystal Structure of an Active Form of BACE1, an Enzyme Responsible for Amyloid   Protein Production

(2008) H. Shimizu et al.   MOLECULAR AND CELLULAR BIOLOGY

LRP1 modulates APP trafficking along early compartments of the secretory pathway

(2008) Elaine Waldron et al.   NEUROBIOLOGY OF DISEASE

Efficient Inhibition of the Alzheimer's Disease  -Secretase by Membrane Targeting

(2008) L. Rajendran et al.   SCIENCE