ATP6V0C Knockdown in Neuroblastoma Cells Alters Autophagy-Lysosome Pathway Function and Metabolism of Proteins that Accumulate in Neurodegenerative Disease

14-3-3ε and NAV2 interact to regulate neurite outgrowth and axon elongation

(2013) Mark A. Marzinke et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies

(2013) Claudia Manzoni et al.   FASEB JOURNAL

p62/SQSTM1-Dependent Autophagy of Lewy Body-Like α-Synuclein Inclusions

(2013) Yoshihisa Watanabe et al.   PLoS One

Rotenone Inhibits Autophagic Flux Prior to Inducing Cell Death

(2012) Burton J. Mader et al.   ACS Chemical Neuroscience

Protein degradation pathways in Parkinson’s disease: curse or blessing

(2012) Darius Ebrahimi-Fakhari et al.   ACTA NEUROPATHOLOGICA

Alpha-synuclein aggregation involves a bafilomycin A1-sensitive autophagy pathway

(2012) Jochen Klucken et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Mouse models of neuronal ceroid lipofuscinoses: Useful pre-clinical tools to delineate disease pathophysiology and validate therapeutics

(2012) John J. Shacka   BRAIN RESEARCH BULLETIN

Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease

(2012) Marzena Kurzawa-Akanbi et al.   JOURNAL OF NEUROCHEMISTRY

Lysosome-dependent pathways as a unifying theme in Parkinson's disease

(2012) George K. Tofaris   MOVEMENT DISORDERS

Dopamine release via the vacuolar ATPase V0 sector c-subunit, confirmed in N18 neuroblastoma cells, results in behavioral recovery in hemiparkinsonian mice

(2012) Duo Jin et al.   NEUROCHEMISTRY INTERNATIONAL

Cystatin C in Alzheimer's disease

(2012) Gurjinder Kaur et al.   Frontiers in Molecular Neuroscience

Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

(2011) Joseph R. Mazzulli et al.   CELL

Regulation of TFEB and V-ATPases by mTORC1

(2011) Samuel Peña-Llopis et al.   EMBO JOURNAL

Vacuolar H+-ATPase c protects glial cell death induced by sodium nitroprusside under glutathione-depleted condition

(2011) Yu Jeong Byun et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Distinct Roles In Vivo for the Ubiquitin-Proteasome System and the Autophagy-Lysosomal Pathway in the Degradation of  -Synuclein

(2011) D. Ebrahimi-Fakhari et al.   JOURNAL OF NEUROSCIENCE

Control of autophagy as a therapy for neurodegenerative disease

(2011) Harry Harris et al.   Nature Reviews Neurology

Autophagy failure in Alzheimer's disease—locating the primary defect

(2011) Ralph A. Nixon et al.   NEUROBIOLOGY OF DISEASE

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Regulation and Isoform Function of the V-ATPases

(2010) Masashi Toei et al.   BIOCHEMISTRY

V-ATPase Membrane Sector Associates with Synaptobrevin to Modulate Neurotransmitter Release

(2010) Jérôme Di Giovanni et al.   NEURON

Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells

(2009) Haiyan You et al.   CANCER LETTERS

Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in  -Synuclein Models of Parkinson's and Lewy Body Diseases

(2009) B. Spencer et al.   JOURNAL OF NEUROSCIENCE

VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease

(2009) Qingmin Ruan et al.   NEUROBIOLOGY OF DISEASE

Oxidative Stress and Autophagy in the Regulation of Lysosome-Dependent Neuron Death

(2008) Violetta N. Pivtoraiko et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

(2008) Edward D. Plowey et al.   JOURNAL OF NEUROCHEMISTRY

The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy

(2007) John et al.   Frontiers in Bioscience-Landmark