HMG-CoA Reductase Inhibitor Statins Activate the Transcriptional Activity of p53 by Regulating the Expression of TAZ

Periplocin and cardiac glycosides suppress the unfolded protein response

(2021) Muneshige Tokugawa et al.   Scientific Reports

The potential use of simvastatin for cancer treatment: A review

(2021) Jaqueline Aparecida Duarte et al.   BIOMEDICINE & PHARMACOTHERAPY

Adaptive homeostasis and the p53 isoform network

(2021) Sunali Mehta et al.   EMBO REPORTS

Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence

(2020) Chiharu Miyajima et al.   Cells

The Innovative Potential of Statins in Cancer: New Targets for New Therapies

(2020) Elisabetta Di Bello et al.   Frontiers in Chemistry

Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin

(2020) Yuhao Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ubiquitin-specific protease USP17 prevents cellular senescence by stabilizing the methyltransferase SET8 and transcriptionally repressing p21

(2019) Keishi Fukuura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-Tumorigenic Activity of Chrysin from Oroxylum indicum via Non-Genotoxic p53 Activation through the ATM-Chk2 Pathway

(2018) Mai Nagasaka et al.   MOLECULES

The CDK inhibitor p21 is a novel target gene of ATF4 and contributes to cell survival under ER stress

(2017) Yasumichi Inoue et al.   FEBS LETTERS

The nonreceptor tyrosine kinase c-Src attenuates SCF(β-TrCP) E3-ligase activity abrogating Taz proteasomal degradation

(2017) Matan Shanzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Prognostic significance of TAZ expression in various cancers: a meta-analysis

(2016) Zhengyu Li et al.   OncoTargets and Therapy

TGF-β induces p53/Smads complex formation in the PAI-1 promoter to activate transcription

(2016) Yuki Kawarada et al.   Scientific Reports

Positive Regulation of Interleukin-2 Expression by a Pseudokinase, Tribbles 1, in Activated T Cells

(2015) Chiharu Miyajima et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers

(2015) Yusuke Oku et al.   FEBS Open Bio

Metabolic control of YAP and TAZ by the mevalonate pathway

(2014) Giovanni Sorrentino et al.   NATURE CELL BIOLOGY

p53 Acetylation: Regulation and Consequences

(2014) Sara Reed et al.   Cancers

Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer Cells

(2013) Lijuan Wang et al.   PLoS One

Nutlin-3, the small-molecule inhibitor of MDM2, promotes senescence and radiosensitises laryngeal carcinoma cells harbouring wild-type p53

(2010) A K Arya et al.   BRITISH JOURNAL OF CANCER

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT