Microcin MccI47 selectively inhibits enteric bacteria and reduces carbapenem-resistant Klebsiella pneumoniae colonization in vivo when administered via an engineered live biotherapeutic

Colonization of the live biotherapeutic product VE303 and modulation of the microbiota and metabolites in healthy volunteers

(2022) Melissa Dsouza et al.   Cell Host & Microbe

Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis

(2021) Matthew F. Wipperman et al.   Nature Communications

Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering

(2021) Kristin J. Adolfsen et al.   Nature Communications

Microcin H47: A Class IIb Microcin with Potent Activity Against Multidrug Resistant Enterobacteriaceae

(2020) Jacob D. Palmer et al.   ACS Infectious Diseases

Bacterial, Gut Microbiome-Modifying Therapies to Defend against Multidrug Resistant Organisms

(2020) Amy Feehan et al.   Microorganisms

Key Takeaways From the U.S. CDC’s 2019 Antibiotic Resistance Threats Report for Frontline Providers

(2020) Sameer S. Kadri   CRITICAL CARE MEDICINE

Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity

(2020) Daniel S. Leventhal et al.   Nature Communications

Developing a new class of engineered live bacterial therapeutics to treat human diseases

(2020) Mark R. Charbonneau et al.   Nature Communications

Probiotic Properties of Escherichia coli Nissle in Human Intestinal Organoids

(2020) Suman Pradhan et al.   mBio

Animal Model To Study Klebsiella pneumoniae Gastrointestinal Colonization and Host-to-Host Transmission

(2020) Taylor M. Young et al.   INFECTION AND IMMUNITY

Plasmid Vectors for in Vivo Selection-Free Use with the Probiotic E. coli Nissle 1917

(2020) Anton Kan et al.   ACS Synthetic Biology

Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut

(2019) Nathan Crook et al.   Cell Host & Microbe

The Evolution and Ecology of Bacterial Warfare

(2019) Elisa T. Granato et al.   CURRENT BIOLOGY

Gut Microbiota Modulation for Multidrug-Resistant Organism Decolonization: Present and Future Perspectives

(2019) Livia Gargiullo et al.   Frontiers in Microbiology

Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae

(2019) Jing Yuan et al.   Cell Metabolism

Microcins in Enterobacteriaceae: Peptide Antimicrobials in the Eco-Active Intestinal Chemosphere

(2019) Fernando Baquero et al.   Frontiers in Microbiology

Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut

(2019) Pichet Praveschotinunt et al.   Nature Communications

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria

(2018) Vincent M Isabella et al.   NATURE BIOTECHNOLOGY

Learning from bacterial competition in the host to develop antimicrobials

(2018) Manuela Raffatellu   NATURE MEDICINE

Synthetic Biology and Engineered Live Biotherapeutics: Toward Increasing System Complexity

(2018) Tanel Ozdemir et al.   Cell Systems

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis

(2018) Alessandro Cassini et al.   LANCET INFECTIOUS DISEASES

Enteric coatings for colonic drug delivery: state of the art

(2017) Alessandra Maroni et al.   Expert Opinion on Drug Delivery

lmerTest Package: Tests in Linear Mixed Effects Models

(2017) Alexandra Kuznetsova et al.   Journal of Statistical Software

The evolution of the host microbiome as an ecosystem on a leash

(2017) Kevin R. Foster et al.   NATURE

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation

(2017) Koji Atarashi et al.   SCIENCE

Engineered Probiotic for the Inhibition of Salmonella via Tetrathionate-Induced Production of Microcin H47

(2017) Jacob D. Palmer et al.   ACS Infectious Diseases

Antimicrobial Probiotics Reduce Salmonella enterica in Turkey Gastrointestinal Tracts

(2017) Brittany Forkus et al.   Scientific Reports

Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics

(2016) Verena Hoerr et al.   BMC MICROBIOLOGY

Decolonization in Prevention of Health Care-Associated Infections

(2016) Edward J. Septimus et al.   CLINICAL MICROBIOLOGY REVIEWS

Microcins mediate competition among Enterobacteriaceae in the inflamed gut

(2016) Martina Sassone-Corsi et al.   NATURE

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

Evolution and Dissemination of OqxAB-Like Efflux Pumps, an Emerging Quinolone Resistance Determinant among Members of Enterobacteriaceae

(2015) Marcus Ho Yin Wong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

(2014) Charlie G. Buffie et al.   NATURE

Easyfig: a genome comparison visualizer

(2011) M. J. Sullivan et al.   BIOINFORMATICS

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

Shifting the balance: antibiotic effects on host–microbiota mutualism

(2011) Benjamin P. Willing et al.   NATURE REVIEWS MICROBIOLOGY

Design, construction and characterization of a set of insulated bacterial promoters

(2010) J. H. Davis et al.   NUCLEIC ACIDS RESEARCH

Isolation and Characterization of Two Members of the Siderophore-Microcin Family, Microcins M and H47

(2009) G. Vassiliadis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS