Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics

Fructose Restores Susceptibility of Multidrug-Resistant Edwardsiella tarda to Kanamycin

(2015) Yu-bin Su et al.   JOURNAL OF PROTEOME RESEARCH

Time for a change: addressing R&D and commercialization challenges for antibacterials

(2015) D. J. Payne et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Detection of vancomycin resistances in enterococci within 3 ½ hours

(2015) U. -Ch. Schröder et al.   Scientific Reports

Impact of Antibiotics with Various Target Sites on the Metabolome of Staphylococcus aureus

(2014) Kirsten Dörries et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

antibacTR: dynamic antibacterial-drug-target ranking integrating comparative genomics, structural analysis and experimental annotation

(2014) Alejandro Panjkovich et al.   BMC GENOMICS

Identification of potential drug targets in Salmonella enterica sv. Typhimurium using metabolic modelling and experimental validation

(2014) Hassan B. Hartman et al.   MICROBIOLOGY-SGM

Metabolomic approach to optimizing and evaluating antibiotic treatment in the axenic culture of cyanobacterium Nostoc flagelliforme

(2014) Pei-pei Han et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Evaluation of antibiotic effects on Pseudomonas aeruginosa biofilm using Raman spectroscopy and multivariate analysis

(2014) Gyeong Bok Jung et al.   Biomedical Optics Express

Quantitative proteomics to study carbapenem resistance in Acinetobacter baumannii

(2014) Vishvanath Tiwari et al.   Frontiers in Microbiology

Platforms for antibiotic discovery

(2013) Kim Lewis   NATURE REVIEWS DRUG DISCOVERY

Role of glutamate metabolism in bacterial responses towards acid and other stresses

(2012) C. Feehily et al.   JOURNAL OF APPLIED MICROBIOLOGY

Predicting the in Vivo Mechanism of Action for Drug Leads Using NMR Metabolomics

(2011) Steven Halouska et al.   ACS Chemical Biology

Applications of system-level models of metabolism for analysis of bacterial physiology and identification of new drug targets

(2011) A. Navid   Briefings in Functional Genomics

Novel classes of antibiotics or more of the same?

(2011) Anthony RM Coates et al.   BRITISH JOURNAL OF PHARMACOLOGY

Monitoring the Effects of Chiral Pharmaceuticals on Aquatic Microorganisms by Metabolic Fingerprinting

(2010) E. S. Wharfe et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Discovery of novel antibacterials

(2010) J Richard Miller et al.   Expert Opinion on Drug Discovery

Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds

(2009) Naz M. Aghatabay et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria

(2009) D. G. Kurth et al.   MICROBIOLOGY-SGM

Drug Discovery Using Chemical Systems Biology: Repositioning the Safe Medicine Comtan to Treat Multi-Drug and Extensively Drug Resistant Tuberculosis

(2009) Sarah L. Kinnings et al.   PLoS Computational Biology

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Global trends in emerging infectious diseases

(2008) Kate E. Jones et al.   NATURE