Zinc-doped Prussian blue nanoparticles for mutp53-carrying tumor ion interference and photothermal therapy

Copper-based theranostic nanocatalysts for synergetic photothermal-chemodynamic therapy

(2022) Wenbao Zuo et al.   Acta Biomaterialia

Glutathionylation-dependent proteasomal degradation of wide-spectrum mutant p53 proteins by engineered zeolitic imidazolate framework-8

(2021) Yunjiao Zhang et al.   BIOMATERIALS

Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 Degradation

(2020) Alessia Garufi et al.   Biomolecules

Tumor‐Microenvironment‐Triggered Ion Exchange of a Metal–Organic Framework Hybrid for Multimodal Imaging and Synergistic Therapy of Tumors

(2020) Ying Chen et al.   ADVANCED MATERIALS

Copper‐Enriched Prussian Blue Nanomedicine for In Situ Disulfiram Toxification and Photothermal Antitumor Amplification

(2020) Wencheng Wu et al.   ADVANCED MATERIALS

Smart gold nanocages for mild heat-triggered drug release and breaking chemoresistance

(2020) Huamei He et al.   JOURNAL OF CONTROLLED RELEASE

Gain-of-function mutant p53 in cancer progression and therapy

(2020) Cen Zhang et al.   Journal of Molecular Cell Biology

Enhancing Chemotherapy of p53‐Mutated Cancer through Ubiquitination‐Dependent Proteasomal Degradation of Mutant p53 Proteins by Engineered ZnFe‐4 Nanoparticles

(2020) Jieying Qian et al.   ADVANCED FUNCTIONAL MATERIALS

Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival

(2019) Giorgia Foggetti et al.   BIOSCIENCE REPORTS

Zinc-doped Prussian blue enhances photothermal clearance of Staphylococcus aureus and promotes tissue repair in infected wounds

(2019) Jun Li et al.   Nature Communications

Medical Therapy of Patients Contaminated with Radioactive Cesium or Iodine

(2019) Jan Aaseth et al.   Biomolecules

USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells

(2018) Achuth Padmanabhan et al.   Nature Communications

Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target

(2018) Ramona Schulz-Heddergott et al.   Cancers

The most popular genes in the human genome

(2017)   NATURE

Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others

(2017) Kanaga Sabapathy et al.   Nature Reviews Clinical Oncology

The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

(2016) Andreas C. Joerger et al.   Annual Review of Biochemistry

Nanotechnology in hyperthermia cancer therapy: From fundamental principles to advanced applications

(2016) Jaber Beik et al.   JOURNAL OF CONTROLLED RELEASE

Reactivation of mutant p53 by capsaicin, the major constituent of peppers

(2016) Alessia Garufi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway

(2016) Alejandro Parrales et al.   NATURE CELL BIOLOGY

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53

(2015) Shengliang Zhang et al.   CANCER RESEARCH

Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment

(2015) E. M. Alexandrova et al.   NATURE

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

(2015) Flore Kruiswijk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Novel Insights into Combating Cancer Chemotherapy Resistance Using a Plasmonic Nanocarrier: Enhancing Drug Sensitiveness and Accumulation Simultaneously with Localized Mild Photothermal Stimulus of Femtosecond Pulsed Laser

(2014) Liming Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Ganetespib and HSP90: Translating Preclinical Hypotheses into Clinical Promise

(2014) D. A. Proia et al.   CANCER RESEARCH

Degradation of mutant p53H175 protein by Zn(II) through autophagy

(2014) A Garufi et al.   Cell Death & Disease

Effect of zinc oxide nanomaterials-induced oxidative stress on the p53 pathway

(2013) Magdiel I. Setyawati et al.   BIOMATERIALS

Dissecting the pathways that destabilize mutant p53: The proteasome or autophagy?

(2013) Sujata Choundhury et al.   CELL CYCLE

A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells

(2013) Alessia Garufi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Prussian blue nanoparticles operate as a new generation of photothermal ablation agents for cancer therapy

(2012) Guanglei Fu et al.   CHEMICAL COMMUNICATIONS

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs

(2011) Rosa Puca et al.   CELL CYCLE

Mutant p53 Protein Is Targeted by Arsenic for Degradation and Plays a Role in Arsenic-mediated Growth Suppression

(2011) Wensheng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Inactivation of Endogenous MDM2 and CHIP by HSP90 Causes Aberrant Stabilization of Mutant p53 in Human Cancer Cells

(2011) D. Li et al.   MOLECULAR CANCER RESEARCH

Dual purpose Prussian blue nanoparticles for cellular imaging and drug delivery: a new generation of T1-weighted MRI contrast and small molecule delivery agents

(2010) Mohammadreza Shokouhimehr et al.   JOURNAL OF MATERIALS CHEMISTRY

The missing Zinc: p53 misfolding and cancer

(2010) Stewart N. Loh   Metallomics