Fibroblast growth factor 7 alleviates myocardial infarction by improving oxidative stress via PI3Kα/AKT-mediated regulation of Nrf2 and HXK2

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

(2022) Connie W. Tsao et al.   CIRCULATION

The protective effects of fibroblast growth factor 10 against hepatic ischemia-reperfusion injury in mice

(2021) Santie Li et al.   Redox Biology

Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction

(2021) Xueyi Chen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nrf2 for cardiac protection: pharmacological options against oxidative stress

(2021) Qin M. Chen   TRENDS IN PHARMACOLOGICAL SCIENCES

Prognostic value of oxidative stress in patients with acute myocardial infarction complicated by cardiogenic shock: A prospective cohort study

(2021) Marie Tomandlova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage

(2020) Shan Deng et al.   Redox Biology

MicroRNA-107 Ameliorates Damage in a Cell Model of Alzheimer’s Disease by Mediating the FGF7/FGFR2/PI3K/Akt Pathway

(2020) Wei Chen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Fibroblast Growth Factors in the Management of Acute Kidney Injury Following Ischemia-Reperfusion

(2020) Lian-Cheng Deng et al.   Frontiers in Pharmacology

Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

(2020) Heiko Bugger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

An inhibitor role of Nrf2 in the regulation of myocardial senescence and dysfunction after myocardial infarction

(2020) Xinxia Luo et al.   LIFE SCIENCES

p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis

(2020) Shengfan Ye et al.   Cell Death & Disease

The myeloid type I interferon response to myocardial infarction begins in bone marrow and is regulated by Nrf2-activated macrophages

(2020) David M. Calcagno et al.   Science Immunology

Inhibition of the FGF/FGFR System Induces Apoptosis in Lung Cancer Cells via c-Myc Downregulation and Oxidative Stress

(2020) Arianna Giacomini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

aFGF alleviates diabetic endothelial dysfunction by decreasing oxidative stress via Wnt/β-catenin-mediated upregulation of HXK2

(2020) Jia Sun et al.   Redox Biology

STAT1‐avtiviated LINC00961 regulates myocardial infarction by the PI3K/AKT/GSK3β signaling pathway

(2019) Shengzhong Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury

(2019) Yuan Liu et al.   JOURNAL OF HEPATOLOGY

Astragaloside IV exerts angiogenesis and cardioprotection after myocardial infarction via regulating PTEN/PI3K/Akt signaling pathway

(2019) Songyi Cheng et al.   LIFE SCIENCES

Long noncoding RNA Linc00460 promotes breast cancer progression by regulating the miR-489-5p/FGF7/AKT axis

(2019) Yong Zhu et al.   Cancer Management and Research

Repair Effects of KGF on Ischemia-Reperfusion–Induced Flap Injury via Activating Nrf2 Signaling

(2019) Yueping Mao et al.   JOURNAL OF SURGICAL RESEARCH

Keratinocyte growth factor protects endometrial cells from oxygen glucose deprivation/re-oxygenation via activating Nrf2 signaling

(2018) Xuting Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial uncoupling, ROS generation and cardioprotection

(2018) Susana Cadenas   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway

(2018) Ying Xin et al.   Redox Biology

Nrf2 expression and function, but not MT expression, is indispensable for sulforaphane-mediated protection against intermittent hypoxia-induced cardiomyopathy in mice

(2018) Shanshan Zhou et al.   Redox Biology

Amentoflavone induces apoptosis and suppresses glycolysis in glioma cells by targeting miR-124-3p

(2018) Wang Zhaohui et al.   NEUROSCIENCE LETTERS

FGF7/FGFR2 signal promotes invasion and migration in human gastric cancer through upregulation of thrombospondin-1

(2017) Tingting Huang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

FGF-dependent metabolic control of vascular development

(2017) Pengchun Yu et al.   NATURE

Normal versus Pathological Cardiac Fibroblast-Derived Extracellular Matrix Differentially Modulates Cardiosphere-Derived Cell Paracrine Properties and Commitment

(2017) Francesca Pagano et al.   Stem Cells International

Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis

(2017) Hongming Lv et al.   Redox Biology

Chlamydia trachomatis Prevents Apoptosis Via Activation of PDPK1-MYC and Enhanced Mitochondrial Binding of Hexokinase II

(2017) Munir A. Al-Zeer et al.   EBioMedicine

Activation of Cannabinoid Receptor Type II by AM1241 Ameliorates Myocardial Fibrosis via Nrf2-Mediated Inhibition of TGF-β1/Smad3 Pathway in Myocardial Infarction Mice

(2016) Xiang Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse HeartNovelty and Significance

(2016) Matthew Ackers-Johnson et al.   CIRCULATION RESEARCH

Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy

(2013) George S Krasnov et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Akt Phosphorylates HK-II at Thr-473 and Increases Mitochondrial HK-II Association to Protect Cardiomyocytes

(2013) David J. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

Lack ofHXK2Induces Localization of Active Ras in Mitochondria and Triggers Apoptosis in the YeastSaccharomyces cerevisiae

(2013) Loredana Amigoni et al.   Oxidative Medicine and Cellular Longevity

Heat Shock Improves Sca-1+Stem Cell Survival and Directs Ischemic Cardiomyocytes Toward a Prosurvival Phenotype Via Exosomal Transfer: A Critical Role for HSF1/miR-34a/HSP70 Pathway

(2013) Yuliang Feng et al.   STEM CELLS

Oxidative stress and cancer: An overview

(2012) Venus Sosa et al.   AGEING RESEARCH REVIEWS

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

(2012) Holly K. Bryan et al.   BIOCHEMICAL PHARMACOLOGY

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

(2012) Houman Ashrafian et al.   Cell Metabolism

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

(2012) S Chowdhry et al.   ONCOGENE

Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death

(2012) E. C. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

(2011) N. Itoh et al.   JOURNAL OF BIOCHEMISTRY

Recent Trends in the Incidence, Treatment, and Outcomes of Patients with STEMI and NSTEMI

(2010) David D. McManus et al.   AMERICAN JOURNAL OF MEDICINE

Sca-1 + Stem Cell Survival and Engraftment in the Infarcted Heart

(2009) Gang Lu et al.   CIRCULATION

Keratinocyte growth factor down-regulates intracellular ROS production induced by UVB

(2009) Daniela Kovacs et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Keratinocyte growth factor: a new mesothelial targeted therapy to reduce postoperative pericardial adhesions☆

(2008) Jackson B. Lopes et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY