Combination of ciprofloxacin/celecoxib as a novel therapeutic strategy for ALS

Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer’s Disease

(2021) Francheska Delgado-Peraza et al.   Cells

Development and validation of a machine-learning ALS survival model lacking vital capacity (VC-Free) for use in clinical trials during the COVID-19 pandemic

(2021) Danielle Beaulieu et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

CNS-Derived Blood Exosomes as a Promising Source of Biomarkers: Opportunities and Challenges

(2020) Simon Hornung et al.   Frontiers in Molecular Neuroscience

Exosomal TAR DNA-binding protein-43 and neurofilaments in plasma of amyotrophic lateral sclerosis patients: A longitudinal follow-up study

(2020) Po-Chih Chen et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Longitudinal biomarkers in amyotrophic lateral sclerosis

(2020) Fen Huang et al.   Annals of Clinical and Translational Neurology

Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis

(2020) Sabrina Paganoni et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of Ciprofloxacin/Celecoxib combination in zebrafish models of amyotrophic lateral sclerosis

(2020) Hagit Goldshtein et al.   Annals of Clinical and Translational Neurology

Diagnostic and Prognostic Performance of Neurofilaments in ALS

(2019) Koen Poesen et al.   Frontiers in Neurology

Iron in Neurodegeneration – Cause or Consequence?

(2019) Alain Ndayisaba et al.   Frontiers in Neuroscience

Safety and tolerability of Triumeq in amyotrophic lateral sclerosis: the Lighthouse trial

(2019) Julian Gold et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

TDP-43 as a potential biomarker for amyotrophic lateral sclerosis: a systematic review and meta-analysis

(2018) Vivek Majumder et al.   BMC Neurology

Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model

(2018) Henk-Jan Westeneng et al.   LANCET NEUROLOGY

Improved stratification of ALS clinical trials using predicted survival

(2018) James D. Berry et al.   Annals of Clinical and Translational Neurology

Long-term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS

(2018) Stephen A. Goutman et al.   Annals of Clinical and Translational Neurology

Pilot trial of inosine to elevate urate levels in amyotrophic lateral sclerosis

(2018) Katharine Nicholson et al.   Annals of Clinical and Translational Neurology

MicroRNAs as Biomarkers in Amyotrophic Lateral Sclerosis

(2018) Claudia Ricci et al.   Cells

TDP-43 and Cytoskeletal Proteins in ALS

(2017) Moritz Oberstadt et al.   MOLECULAR NEUROBIOLOGY

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

(2017) Fiona M. Menzies et al.   NEURON

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms

(2017) Martin Madill et al.   Molecular Brain

Role of Neuroinflammation in Amyotrophic Lateral Sclerosis: Cellular Mechanisms and Therapeutic Implications

(2017) Jia Liu et al.   Frontiers in Immunology

Exosome secretion is a key pathway for clearance of pathological TDP-43

(2016) Yohei Iguchi et al.   BRAIN

Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells

(2015) Sujan Badal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Being PRO-ACTive: What can a Clinical Trial Database Reveal About ALS?

(2015) Neta Zach et al.   Neurotherapeutics

Crowdsourced analysis of clinical trial data to predict amyotrophic lateral sclerosis progression

(2014) Robert Küffner et al.   NATURE BIOTECHNOLOGY

The PRO-ACT database: Design, initial analyses, and predictive features

(2014) N. Atassi et al.   NEUROLOGY

Model-based dose finding under model uncertainty using general parametric models

(2013) José Pinheiro et al.   STATISTICS IN MEDICINE

Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells

(2010) Shengbing Huang et al.   Autophagy

The use of Cox-2 and PPARγ signaling in anti-cancer therapies

(2010) LUCIA KNOPFOVÁ et al.   Experimental and Therapeutic Medicine

A small molecule enhances RNA interference and promotes microRNA processing

(2008) Ge Shan et al.   NATURE BIOTECHNOLOGY

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

(2008) J. Sreedharan et al.   SCIENCE