Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms
出版年份 2017 全文链接
标题
Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms
作者
关键词
-
出版物
Molecular Brain
Volume 10, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-06-13
DOI
10.1186/s13041-017-0300-4
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS
- (2017) Claire E. Hall et al. Cell Reports
- C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Demen
- (2016) Ruxandra Dafinca et al. STEM CELLS
- Role of autophagy in the pathogenesis of amyotrophic lateral sclerosis
- (2015) Jae Keun Lee et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model
- (2015) Y. Li et al. NEUROSCIENCE
- Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells
- (2015) Zhong-Wei Du et al. Nature Communications
- MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis
- (2014) Xiaojie Zhang et al. Autophagy
- Sqstm1 knock-down causes a locomotor phenotype ameliorated by rapamycin in a zebrafish model of ALS/FTLD
- (2014) Serena Lattante et al. HUMAN MOLECULAR GENETICS
- C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
- (2014) Manal A. Farg et al. HUMAN MOLECULAR GENETICS
- Remembering K. S. Krishnan (1946–2014)
- (2014) Richa Rikhy et al. JOURNAL OF NEUROGENETICS
- Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
- (2014) Sami J Barmada et al. Nature Chemical Biology
- An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non–cell autonomous neurodegeneration
- (2014) Gilbert Gallardo et al. NATURE NEUROSCIENCE
- The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy
- (2014) Mónika Lippai et al. Biomed Research International
- Protein aggregation in amyotrophic lateral sclerosis
- (2013) Anna M. Blokhuis et al. ACTA NEUROPATHOLOGICA
- Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology
- (2013) Elisa Teyssou et al. ACTA NEUROPATHOLOGICA
- Delineating the genetic heterogeneity of ALS using targeted high-throughput sequencing
- (2013) Kevin P Kenna et al. JOURNAL OF MEDICAL GENETICS
- Rapamycin increases survival in ALS mice lacking mature lymphocytes
- (2013) Kim A Staats et al. Molecular Neurodegeneration
- Global Epidemiology of Amyotrophic Lateral Sclerosis: A Systematic Review of the Published Literature
- (2013) A. Chiò et al. NEUROEPIDEMIOLOGY
- Striatal Infusion of Glial Conditioned Medium Diminishes Huntingtin Pathology in R6/1 Mice
- (2013) Juan Perucho et al. PLoS One
- Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS
- (2013) K. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
- (2012) Véronique Schaeffer et al. BRAIN
- Mechanisms of Autophagosome Biogenesis
- (2012) David C. Rubinsztein et al. CURRENT BIOLOGY
- Male-Specific Differences in Proliferation, Neurogenesis, and Sensitivity to Oxidative Stress in Neural Progenitor Cells Derived from a Rat Model of ALS
- (2012) Ruojia Li et al. PLoS One
- Neuronal Autophagy: A Housekeeper or a Fighter in Neuronal Cell Survival?
- (2012) Jin-A Lee Experimental Neurobiology
- Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis
- (2011) Shoichi Sasaki JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Amyotrophic lateral sclerosis
- (2011) Matthew C Kiernan et al. LANCET
- Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
- (2011) Amanda M Haidet-Phillips et al. NATURE BIOTECHNOLOGY
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- TDP-43 and ubiquitinated cytoplasmic aggregates in sporadic ALS are low frequency and widely distributed in the lower motor neuron columns independent of disease spread
- (2010) Aaron Bodansky et al. Amyotrophic Lateral Sclerosis
- Regulation of TDP-43 aggregation by phosphorylation andp62/SQSTM1
- (2010) Owen A. Brady et al. JOURNAL OF NEUROCHEMISTRY
- Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
- (2010) Daryl A Bosco et al. NATURE NEUROSCIENCE
- Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS)
- (2010) Laura E. Cox et al. PLoS One
- Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism
- (2009) Jozsef Gal et al. JOURNAL OF NEUROCHEMISTRY
- Age and founder effect of SOD1 A4V mutation causing ALS
- (2009) M. Saeed et al. NEUROLOGY
- Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
- (2008) Maria C.N. Marchetto et al. Cell Stem Cell
- Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation
- (2008) Francesco Paolo Di Giorgio et al. Cell Stem Cell
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