Restoration of mitochondria axonal transport by adaptor Disc1 supplementation prevents neurodegeneration and rescues visual function

Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma

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Intravital deep-tumor single-beam 3-photon, 4-photon, and harmonic microscopy

(2022) Gert-Jan Bakker et al.   eLife

Selective motor activation in organelle transport along axons

(2022) Sydney E. Cason et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Predicting Mitochondrial Dynamic Behavior in Genetically Defined Neurodegenerative Diseases

(2022) Gerald W. Dorn et al.   Cells

Metaxins are core components of mitochondrial transport adaptor complexes

(2021) Yinsuo Zhao et al.   Nature Communications

Local Accumulation of Axonal Mitochondria in the Optic Nerve Glial Lamina Precedes Myelination

(2021) Samantha J. Wilkison et al.   Frontiers in Neuroanatomy

AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma

(2021) Nicolas Belforte et al.   Molecular Neurodegeneration

Mitochondrial Ca2+ Signaling in Health, Disease and Therapy

(2021) Lorenzo Modesti et al.   Cells

Restoring Cellular Energetics Promotes Axonal Regeneration and Functional Recovery after Spinal Cord Injury

(2020) Qi Han et al.   Cell Metabolism

Miro: A molecular switch at the center of mitochondrial regulation

(2020) Emily L. Eberhardt et al.   PROTEIN SCIENCE

Interpericyte tunnelling nanotubes regulate neurovascular coupling

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Miro, a Rho GTPase genetically interacts with Alzheimer's disease-associated genes (Tau, Aβ42 and Appl) in Drosophila melanogaster

(2020) Komal Panchal et al.   Biology Open

DISC1 Regulates Mitochondrial Trafficking in a Miro1-GTP-Dependent Manner

(2020) Rosalind Norkett et al.   Frontiers in Cell and Developmental Biology

Anterograde Axonal Transport in Neuronal Homeostasis and Disease

(2020) Laurent Guillaud et al.   Frontiers in Molecular Neuroscience

Mitochondrial transport serves as a mitochondrial quality control strategy in axons: Implications for central nervous system disorders

(2019) Yan‐Rong Zheng et al.   CNS Neuroscience & Therapeutics

Axonal Transport and Mitochondrial Function in Neurons

(2019) Amrita Mandal et al.   Frontiers in Cellular Neuroscience

Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution

(2018) Guillermo López‐Doménech et al.   EMBO JOURNAL

The effects of age on mitochondria, axonal transport, and axonal degeneration after chronic IOP elevation using a murine ocular explant model

(2018) Elizabeth C. Kimball et al.   EXPERIMENTAL EYE RESEARCH

ER stress and unfolded protein response in ocular health and disease

(2018) Heike Kroeger et al.   FEBS Journal

Disrupted-in-schizophrenia-1 protects synaptic plasticity in a transgenic mouse model of Alzheimer’s disease as a mitophagy receptor

(2018) Zhao-Tao Wang et al.   AGING CELL

Glaucoma as a Metabolic Optic Neuropathy

(2017) Pete A. Williams et al.   JOURNAL OF GLAUCOMA

Mitochondrial dynamics, transport, and quality control: A bottleneck for retinal ganglion cell viability in optic neuropathies

(2017) Yoko A. Ito et al.   MITOCHONDRION

Use of luciferase probes to measure ATP in living cells and animals

(2017) Giampaolo Morciano et al.   Nature Protocols

Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions

(2017) Mei-Yao Lin et al.   NEURON

Regulation of mitochondrial dynamics by DISC1, a putative risk factor for major mental illness

(2017) Laura C. Murphy et al.   SCHIZOPHRENIA RESEARCH

Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

(2017) Pete A. Williams et al.   SCIENCE

Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma

(2017) Denise M. Inman et al.   Frontiers in Neuroscience

Four alpha ganglion cell types in mouse retina: Function, structure, and molecular signatures

(2017) Brenna Krieger et al.   PLoS One

Electroretinography in glaucoma diagnosis

(2016) Laura J. Wilsey et al.   CURRENT OPINION IN OPHTHALMOLOGY

Glaucoma: Focus on mitochondria in relation to pathogenesis and neuroprotection

(2016) Neville N. Osborne et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Selective Vulnerability of Specific Retinal Ganglion Cell Types and Synapses after Transient Ocular Hypertension

(2016) Y. Ou et al.   JOURNAL OF NEUROSCIENCE

The glial cell modulator ibudilast attenuates neuroinflammation and enhances retinal ganglion cell viability in glaucoma through protein kinase A signaling

(2016) Jorge L. Cueva Vargas et al.   NEUROBIOLOGY OF DISEASE

The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration

(2016) Romain Cartoni et al.   NEURON

Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites

(2016) Guillermo López-Doménech et al.   Cell Reports

Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring

(2016) Cana Park et al.   Molecular Brain

Psychophysical testing in rodent models of glaucomatous optic neuropathy

(2015) Stephanie L. Grillo et al.   EXPERIMENTAL EYE RESEARCH

DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites

(2015) Rosalind Norkett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disrupted-in-Schizophrenia-1 Attenuates Amyloid-β Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of β-Site APP-Cleaving Enzyme 1 Levels

(2015) Qing-Shan Deng et al.   NEUROPSYCHOPHARMACOLOGY

In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS

(2015) Yuji Takihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury

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Odorant Concentration Differentiator for Intermittent Olfactory Signals

(2014) T. Fujiwara et al.   JOURNAL OF NEUROSCIENCE

Unique Function of Kinesin Kif5A in Localization of Mitochondria in Axons

(2014) P. D. Campbell et al.   JOURNAL OF NEUROSCIENCE

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

(2014) Yih-Chung Tham et al.   OPHTHALMOLOGY

Inhibitor of Apoptosis-Stimulating Protein of p53 (iASPP) Is Required for Neuronal Survival after Axonal Injury

(2014) Ariel M. Wilson et al.   PLoS One

Transcellular degradation of axonal mitochondria

(2014) Chung-ha O. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age

(2013) Andrew W Ferree et al.   Autophagy

DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking

(2013) Fumiaki Ogawa et al.   HUMAN MOLECULAR GENETICS

The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina

(2013) Allen R. Rodriguez et al.   JOURNAL OF COMPARATIVE NEUROLOGY

ASPP1/2 Regulate p53-Dependent Death of Retinal Ganglion Cells through PUMA and Fas/CD95 Activation In Vivo

(2013) A. M. Wilson et al.   JOURNAL OF NEUROSCIENCE

Imaging axonal transport in the rat visual pathway

(2013) Carla J. Abbott et al.   Biomedical Optics Express

Under Pressure: Cellular and Molecular Responses During Glaucoma, a Common Neurodegeneration with Axonopathy

(2012) Robert W. Nickells et al.   Annual Review of Neuroscience

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration

(2012) Zu-Hang Sheng et al.   NATURE REVIEWS NEUROSCIENCE

Synaptic Energy Use and Supply

(2012) Julia J. Harris et al.   NEURON

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

A cell-permeable phosphine-borane complex delays retinal ganglion cell death after axonal injury through activation of the pro-survival extracellular signal-regulated kinases 1/2 pathway

(2011) Mohammadali Almasieh et al.   JOURNAL OF NEUROCHEMISTRY

Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networks

(2010) Olga S. Koutsopoulos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons

(2010) T A Atkin et al.   MOLECULAR PSYCHIATRY

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

(2010) S. D. Crish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disrupted-in-schizophrenia1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin

(2010) Young-Un Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERG changes in albino and pigmented mice after optic nerve transection

(2010) Luis Alarcón-Martínez et al.   VISION RESEARCH

Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders

(2009) Valerio Carelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Heterogeneous Distribution of Axonal Cytoskeleton Proteins in the Human Optic Nerve

(2009) C. Balaratnasingam et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial biogenesis in the axons of vertebrate peripheral neurons

(2008) Mandana Amiri et al.   Developmental Neurobiology

Dendritic and Synaptic Protection: Is It Enough to Save the Retinal Ganglion Cell Body and Axon?

(2008) Junie Barbara Morquette et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

(2008) M. Saotome et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA