Accelerated spread of antibiotic resistance genes (ARGs) induced by non-antibiotic conditions: Roles and mechanisms

Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge

(2022) Dongjuan Dai et al.   Microbiome

Sublethal concentrations of heavy metals Cu2+ and Zn2+ can induce the emergence of bacterial multidrug resistance

(2022) Yan Xu et al.   Environmental Technology & Innovation

Molecular mechanism of antibiotic resistance induced by mono- and twin-chained quaternary ammonium compounds

(2022) Yin Jia et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

(2021) Jerónimo Rodríguez-Beltrán et al.   NATURE REVIEWS MICROBIOLOGY

Nonnutritive sweeteners can promote the dissemination of antibiotic resistance through conjugative gene transfer

(2021) Zhigang Yu et al.   ISME Journal

Non-antibiotic pharmaceuticals promote the transmission of multidrug resistance plasmids through intra- and intergenera conjugation

(2021) Yue Wang et al.   ISME Journal

Potential of 1-(1-napthylmethyl)-piperazine, an efflux pump inhibitor against cadmium-induced multidrug resistance in Salmonella enterica serovar Typhi as an adjunct to antibiotics

(2021) Ujjwal Jit Kaur et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Pervasive transmission of a carbapenem resistance plasmid in the gut microbiota of hospitalized patients

(2021) Ricardo León-Sampedro et al.   Nature Microbiology

Co-effect of cadmium and iron oxide nanoparticles on plasmid-mediated conjugative transfer of antibiotic resistance genes

(2021) Qiang Pu et al.   ENVIRONMENT INTERNATIONAL

Impact of Urbanization on Antibiotic Resistome in Different Microplastics: Evidence from a Large-Scale Whole River Analysis

(2021) Ruilong Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Evaluating the effect of gradient applied voltages on antibiotic resistance genes proliferation and biogas production in anaerobic electrochemical membrane bioreactor

(2021) Zheng-Hao Li et al.   JOURNAL OF HAZARDOUS MATERIALS

Acetaminophen promotes horizontal transfer of plasmid-borne multiple antibiotic resistance genes

(2021) Yuqian Jia et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A systematic review of antibiotics and antibiotic resistance genes in estuarine and coastal environments

(2021) Dongsheng Zheng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Degradation and deactivation of plasmid-encoded antibiotic resistance genes during exposure to ozone and chlorine

(2021) Younggun Yoon et al.   WATER RESEARCH

Temperature and Nutrient Limitations Decrease Transfer of Conjugative IncP-1 Plasmid pKJK5 to Wild Escherichia coli Strains

(2021) Rebeca Pallares-Vega et al.   Frontiers in Microbiology

Enhanced propagation of intracellular and extracellular antibiotic resistance genes in municipal wastewater by microplastics

(2021) Yuan Cheng et al.   ENVIRONMENTAL POLLUTION

Enhancement of antibiotic resistance dissemination by artificial sweetener acesulfame potassium: Insights from cell membrane, enzyme, energy supply and transcriptomics

(2021) Ziqiao Li et al.   JOURNAL OF HAZARDOUS MATERIALS

Horizontal gene transfer and adaptive evolution in bacteria

(2021) Brian J. Arnold et al.   NATURE REVIEWS MICROBIOLOGY

Why Do Antibiotics Exist?

(2021) Fabrizio Spagnolo et al.   mBio

Varying characteristics and driving mechanisms of antibiotic resistance genes in farmland soil amended with high-density polyethylene microplastics

(2021) Xiao-Ming Lu et al.   JOURNAL OF HAZARDOUS MATERIALS

Ionic Liquid Enriches the Antibiotic Resistome, Especially Efflux Pump Genes, Before Significantly Affecting Microbial Community Structure

(2020) Xiaolong Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The impaired quorum sensing response of MexAB‐OprM efflux pump overexpressing mutants is not due to non‐physiological efflux of 3‐oxo‐C12‐HSL

(2020) Manuel Alcalde‐Rico et al.   ENVIRONMENTAL MICROBIOLOGY

CeO2 Nanoparticles Regulate the Propagation of Antibiotic Resistance Genes by Altering Cellular Contact and Plasmid Transfer

(2020) Kaiqiang Yu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Non-antibiotic pharmaceuticals enhance the transmission of exogenous antibiotic resistance genes through bacterial transformation

(2020) Yue Wang et al.   ISME Journal

Marine Plastic Debris: A New Surface for Microbial Colonization

(2020) Robyn J. Wright et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Nano-Al2O3 can mediate transduction-like transformation of antibiotic resistance genes in water

(2020) Chengshi Ding et al.   JOURNAL OF HAZARDOUS MATERIALS

A review of bioelectrochemical systems for antibiotic removal: Efficient antibiotic removal and dissemination of antibiotic resistance genes

(2020) Shuai Zhang et al.   Journal of Water Process Engineering

Will a Non-antibiotic Metalloid Enhance the Spread of Antibiotic Resistance Genes: The Selenate Story

(2020) Ling-Dong Shi et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A survey of sub-inhibitory concentrations of antibiotics in the environment

(2020) Louise K.M. Chow et al.   Journal of Environmental Sciences-China

Fecal pollution can explain antibiotic resistance gene abundances in anthropogenically impacted environments

(2019) Antti Karkman et al.   Nature Communications

Higher Temperatures Do Not Always Achieve Better Antibiotic Resistance Gene Removal in Anaerobic Digestion of Swine Manure

(2019) Xu Huang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Water Disinfection Byproducts Increase Natural Transformation Rates of Environmental DNA in Acinetobacter baylyi ADP1

(2019) David Mantilla-Calderon et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Host bacterial community of MGEs determines the risk of horizontal gene transfer during composting of different animal manures

(2019) Longji Zhu et al.   ENVIRONMENTAL POLLUTION

Decoupling the Dynamics of Bacterial Taxonomy and Antibiotic Resistance Function in a Subtropical Urban Reservoir as Revealed by High-Frequency Sampling

(2019) Peiju Fang et al.   Frontiers in Microbiology

Prevalence and proliferation of antibiotic resistance genes in the subtropical mangrove wetland ecosystem of South China Sea

(2019) Huaxian Zhao et al.   MicrobiologyOpen

CO2 promotes the conjugative transfer of multiresistance genes by facilitating cellular contact and plasmid transfer

(2019) Junqi Liao et al.   ENVIRONMENT INTERNATIONAL

Copper nanoparticles and copper ions promote horizontal transfer of plasmid-mediated multi-antibiotic resistance genes across bacterial genera

(2019) Shuai Zhang et al.   ENVIRONMENT INTERNATIONAL

Bacterial cross-resistance to anti-infective compounds. Is it a real problem?

(2019) Elizabete de Souza Cândido et al.   CURRENT OPINION IN PHARMACOLOGY

Dissecting horizontal and vertical gene transfer of antibiotic resistance plasmid in bacterial community using microfluidics

(2019) Bing Li et al.   ENVIRONMENT INTERNATIONAL

Potential risks of microplastics combined with superbugs: Enrichment of antibiotic resistant bacteria on the surface of microplastics in mariculture system

(2019) Yuxuan Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Profiles of ARGs and their relationships with antibiotics, metals and environmental parameters in vertical sediment layers of three lakes in China

(2019) Okugbe Ebiotubo Ohore et al.   JOURNAL OF ENVIRONMENTAL MANAGEMENT

Seasonal variations in antibiotic resistance genes in estuarine sediments and the driving mechanisms

(2019) Xiao-Ming Lu et al.   JOURNAL OF HAZARDOUS MATERIALS

Antibiotic resistance genes identified in wastewater treatment plant systems – A review

(2019) Magdalena Pazda et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Aromatic compounds lead to increased abundance of antibiotic resistance genes in wastewater treatment bioreactors

(2019) Juntao Xia et al.   WATER RESEARCH

Effects ofdirect current on Klebsiella spp. viability and corresponding resistance gene expression in simulative bio-electrochemical reactors

(2018) Hua Li et al.   CHEMOSPHERE

Soil types influence the fate of antibiotic-resistant bacteria and antibiotic resistance genes following the land application of sludge composts

(2018) Junya Zhang et al.   ENVIRONMENT INTERNATIONAL

Non-antibiotic antimicrobial triclosan induces multiple antibiotic resistance through genetic mutation

(2018) Ji Lu et al.   ENVIRONMENT INTERNATIONAL

Sub-inhibitory concentrations of heavy metals facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes in water environment

(2018) Ye Zhang et al.   ENVIRONMENTAL POLLUTION

Mechanisms of antimicrobial resistance among hospital-associated pathogens

(2018) Ayesha Khan et al.   Expert Review of Anti-Infective Therapy

The role of TonB-dependent copper receptor in virulence of Acinetobacter baumannii

(2018) Sajad Abdollahi et al.   INFECTION GENETICS AND EVOLUTION

Low-intensity ultrasound promotes the horizontal transfer of resistance genes mediated by plasmids in E. coli

(2018) Lei Song et al.   3 Biotech

A reservoir of ‘historical’ antibiotic resistance genes in remote pristine Antarctic soils

(2018) Marc W. Van Goethem et al.   Microbiome

Low-intensity ultrasound promotes the horizontal transfer of resistance genes mediated by plasmids in E. coli

(2018) Lei Song et al.   3 Biotech

Antidepressant fluoxetine induces multiple antibiotics resistance in Escherichia coli via ROS-mediated mutagenesis

(2018) Min Jin et al.   ENVIRONMENT INTERNATIONAL

A Comprehensive Screening of Escherichia coli Isolates from Scandinavia’s Largest Sewage Treatment Plant Indicates No Selection for Antibiotic Resistance

(2018) Carl-Fredrik Flach et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Do plastics serve as a possible vector for the spread of antibiotic resistance? First insights from bacteria associated to a polystyrene piece from King George Island (Antarctica)

(2018) Pasqualina Laganà et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Seasonal Changes in Antibiotic Resistance Genes in Rivers and Reservoirs in South Korea

(2018) Dae-ik Son et al.   JOURNAL OF ENVIRONMENTAL QUALITY

Diversity of potential antibiotic-resistant bacterial pathogens and the effect of suspended particles on the spread of antibiotic resistance in urban recreational water

(2018) Tingting Fang et al.   WATER RESEARCH

Target (MexB) and efflux based mechanisms decreasing the effectiveness of the efflux pump inhibitor D13-9001 in P. aeruginosa PAO1: uncovering a new role for MexMN-OprM in efflux of β-lactams and a novel regulatory circuit (MmnRS) controlling MexMN expression

(2018) Srijan Ranjitkar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Substituted Aromatic-Facilitated Dissemination of Mobile Antibiotic Resistance Genes via an Antihydrolysis Mechanism Across an Extracellular Polymeric Substance Permeable Barrier

(2018) Weijun Shou et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera

(2018) Yue Wang et al.   ISME Journal

Impact of triclosan adaptation on membrane properties, efflux and antimicrobial resistance of Escherichia coli clinical isolates

(2018) F.I. Sonbol et al.   JOURNAL OF APPLIED MICROBIOLOGY

PAHs accelerate the propagation of antibiotic resistance genes in coastal water microbial community

(2017) Jing Wang et al.   ENVIRONMENTAL POLLUTION

Mutation and recombination in pathogen evolution: Relevance, methods and controversies

(2017) Miguel Arenas et al.   INFECTION GENETICS AND EVOLUTION

Conjugation in Escherichia coli Biofilms on Poly(dimethylsiloxane) Surfaces with Microtopographic Patterns

(2017) Huan Gu et al.   LANGMUIR

Dissemination of antibiotic resistance genes from antibiotic producers to pathogens

(2017) Xinglin Jiang et al.   Nature Communications

Transfer and Persistence of a Multi-Drug Resistance Plasmid in situ of the Infant Gut Microbiota in the Absence of Antibiotic Treatment

(2017) Heidi Gumpert et al.   Frontiers in Microbiology

Distribution of tetracycline resistance genes in anaerobic treatment of waste sludge: The role of pH in regulating tetracycline resistant bacteria and horizontal gene transfer

(2016) Haining Huang et al.   BIORESOURCE TECHNOLOGY

Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation

(2016) Johan Bengtsson-Palme et al.   ENVIRONMENT INTERNATIONAL

Water Disinfection Byproducts Induce Antibiotic Resistance-Role of Environmental Pollutants in Resistance Phenomena

(2016) Dan Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection

(2016) Li-Guan Li et al.   ISME Journal

Effects of electron acceptors on removal of antibiotic resistant Escherichia coli , resistance genes and class 1 integrons under anaerobic conditions

(2016) Heyang Yuan et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Changes of resistome, mobilome and potential hosts of antibiotic resistance genes during the transformation of anaerobic digestion from mesophilic to thermophilic

(2016) Zhe Tian et al.   WATER RESEARCH

Impacts of addition of natural zeolite or a nitrification inhibitor on antibiotic resistance genes during sludge composting

(2016) Junya Zhang et al.   WATER RESEARCH

The Stringent Response Promotes Antibiotic Resistance Dissemination by Regulating Integron Integrase Expression in Biofilms

(2016) Emilie Strugeon et al.   mBio

Induced Bacterial Cross-Resistance toward Host Antimicrobial Peptides: A Worrying Phenomenon

(2016) Osmel Fleitas et al.   Frontiers in Microbiology

Antibiotics as a selective driver for conjugation dynamics

(2016) Allison J. Lopatkin et al.   Nature Microbiology

Mechanism and Effect of Temperature on Variations in Antibiotic Resistance Genes during Anaerobic Digestion of Dairy Manure

(2016) Wei Sun et al.   Scientific Reports

Positive relationship detected between soil bioaccessible organic pollutants and antibiotic resistance genes at dairy farms in Nanjing, Eastern China

(2015) Mingming Sun et al.   ENVIRONMENTAL POLLUTION

Noncovalent Binding of Polycyclic Aromatic Hydrocarbons with Genetic Bases Reducing the in Vitro Lateral Transfer of Antibiotic Resistant Genes

(2015) Fuxing Kang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Distinguishing Effects of Ultraviolet Exposure and Chlorination on the Horizontal Transfer of Antibiotic Resistance Genes in Municipal Wastewater

(2015) Mei-Ting Guo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Antibiotic Resistome and Its Association with Bacterial Communities during Sewage Sludge Composting

(2015) Jian-Qiang Su et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Ionic Liquid Facilitates the Conjugative Transfer of Antibiotic Resistance Genes Mediated by Plasmid RP4

(2015) Qing Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

tet genes as indicators of changes in the water environment: Relationships between culture-dependent and culture-independent approaches

(2015) Monika Harnisz et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Evolution of New Functions De Novo and from Preexisting Genes

(2015) Dan I. Andersson et al.   Cold Spring Harbor Perspectives in Biology

Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism

(2015) Amna Sirelkhatim et al.   Nano-Micro Letters

Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism

(2015) Amna Sirelkhatim et al.   Nano-Micro Letters

The antibiotic resistome: what's new?

(2014) Julie Ann Perry et al.   CURRENT OPINION IN MICROBIOLOGY

The soil resistome: a critical review on antibiotic resistance origins, ecology and dissemination potential in telluric bacteria

(2014) Joseph Nesme et al.   ENVIRONMENTAL MICROBIOLOGY

Dissemination of Antibiotic Resistance Genes in Representative Broiler Feedlots Environments: Identification of Indicator ARGs and Correlations with Environmental Variables

(2014) Liang-Ying He et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The fitness costs of antibiotic resistance mutations

(2014) Anita H. Melnyk et al.   Evolutionary Applications

Role of Pseudomonas aeruginosa AmpR on  -lactam and non- -lactam transient cross-resistance upon pre-exposure to subinhibitory concentrations of antibiotics

(2014) H. Kumari et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Bacterial phylogeny structures soil resistomes across habitats

(2014) Kevin J. Forsberg et al.   NATURE

Pathogens and host immunity in the ancient human oral cavity

(2014) Christina Warinner et al.   NATURE GENETICS

Microbiological effects of sublethal levels of antibiotics

(2014) Dan I. Andersson et al.   NATURE REVIEWS MICROBIOLOGY

The Biology of the PmrA/PmrB Two-Component System: The Major Regulator of Lipopolysaccharide Modifications

(2013) H. Deborah Chen et al.   Annual Review of Microbiology

Regulation of acrAB expression by cellular metabolites in Escherichia coli

(2013) C. Ruiz et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The multiple antibiotic resistance regulator MarR is a copper sensor in Escherichia coli

(2013) Ziyang Hao et al.   Nature Chemical Biology

Antimicrobial activity of metals: mechanisms, molecular targets and applications

(2013) Joseph A. Lemire et al.   NATURE REVIEWS MICROBIOLOGY

Analysis of Triclosan-Selected Salmonella enterica Mutants of Eight Serovars Revealed Increased Aminoglycoside Susceptibility and Reduced Growth Rates

(2013) Ulrike Rensch et al.   PLoS One

Antibiotics as selectors and accelerators of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world

(2013) Juan-Carlos Galán et al.   Frontiers in Microbiology

The multifaceted roles of antibiotics and antibiotic resistance in nature

(2013) Saswati Sengupta et al.   Frontiers in Microbiology

Antimicrobials as promoters of genetic variation

(2012) Jesús Blázquez et al.   CURRENT OPINION IN MICROBIOLOGY

Nanoalumina promotes the horizontal transfer of multiresistance genes mediated by plasmids across genera

(2012) Z. Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metagenomic insights into chlorination effects on microbial antibiotic resistance in drinking water

(2012) Peng Shi et al.   WATER RESEARCH

Involvement of the SmeAB Multidrug Efflux Pump in Resistance to Plant Antimicrobials and Contribution to Nodulation Competitiveness in Sinorhizobium meliloti

(2011) Shima Eda et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Horizontal Gene Exchange in Environmental Microbiota

(2011) Rustam I. Aminov   Frontiers in Microbiology

The Genomic Enzymology of Antibiotic Resistance

(2010) Mariya Morar et al.   Annual Review of Genetics

Integrons

(2010) Guillaume Cambray et al.   Annual Review of Genetics

Inhibition of Free DNA Degradation by the Deformation of DNA Exposed to Trace Polycyclic Aromatic Hydrocarbon Contaminants

(2010) Fuxing Kang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Tetracycline Resistance Genes Persist at Aquaculture Farms in the Absence of Selection Pressure

(2010) Manu Tamminen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Mutation ofnfxBCauses Global Changes in the Physiology and Metabolism ofPseudomonas aeruginosa

(2010) Hannah G. Stickland et al.   JOURNAL OF PROTEOME RESEARCH

Revealing Noncovalent Interactions

(2010) Erin R. Johnson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis

(2010) Michael A. Kohanski et al.   MOLECULAR CELL

Conjugative DNA Transfer Induces the Bacterial SOS Response and Promotes Antibiotic Resistance Development through Integron Activation

(2010) Zeynep Baharoglu et al.   PLoS Genetics

Ribosomal Protein S12 and Aminoglycoside Antibiotics Modulate A-site mRNA Cleavage and Transfer-Messenger RNA Activity in Escherichia coli

(2009) Laura E. Holberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SOS Response Controls Integron Recombination

(2009) E. Guerin et al.   SCIENCE

Antibiotics as signals that trigger specific bacterial responses

(2008) Alicia Fajardo et al.   CURRENT OPINION IN MICROBIOLOGY