PITPNC1 promotes the thermogenesis of brown adipose tissue under acute cold exposure

Adipose Tissue Malfunction Drives Metabolic Dysfunction in Alström Syndrome

(2021) Sona Kang   DIABETES

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

(2021) Long Cheng et al.   Adipocyte

PITPNC1 fuels radioresistance of rectal cancer by inhibiting reactive oxygen species production

(2020) Yujing Tan et al.   Annals of Translational Medicine

Endoplasmic reticulum–associated degradation regulates mitochondrial dynamics in brown adipocytes

(2020) Zhangsen Zhou et al.   SCIENCE

Purine Nucleotides in the Regulation of Brown Adipose Tissue Activity

(2020) Andrea Bast-Habersbrunner et al.   Frontiers in Endocrinology

Ceramides in Adipose Tissue

(2020) Ying Li et al.   Frontiers in Endocrinology

Cold-induced Yes-associated-protein expression through miR-429 mediates the browning of white adipose tissue

(2020) Chenji Ye et al.   Science China-Life Sciences

CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis

(2020) Jian-Wei Hao et al.   Nature Communications

Lauric Acid versus Palmitic Acid: Effects on Adipose Tissue Inflammation, Insulin Resistance, and Non-Alcoholic Fatty Liver Disease in Obesity

(2020) Viswanathan Saraswathi et al.   Biology-Basel

Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes

(2020) Bhagirath Chaurasia et al.   Molecular Metabolism

DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane

(2019) Juan Wang et al.   Cell Reports

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

(2019) María Isabel Hernández-Alvarez et al.   CELL

CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity

(2019) Philipp Hammerschmidt et al.   CELL

Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome

(2019) C. Ronald Kahn et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanistic Links Between Obesity, Diabetes, and Blood Pressure: Role of Perivascular Adipose Tissue

(2019) Sophie N. Saxton et al.   PHYSIOLOGICAL REVIEWS

Brown adipose cross talk in tissue plasticity and human metabolism

(2019) Camilla Scheele et al.   ENDOCRINE REVIEWS

Inhibition of mitochondrial UCP1 and UCP3 by purine nucleotides and phosphate

(2018) Gabriel Macher et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions

(2018) Dijin Xu et al.   JOURNAL OF CELL BIOLOGY

Dynamic role of the transmembrane glycoprotein CD36 (SR-B2) in cellular fatty acid uptake and utilization

(2018) Jan F. C. Glatz et al.   JOURNAL OF LIPID RESEARCH

Degradation of brown adipocyte purine nucleotides regulates uncoupling protein 1 activity

(2018) Tobias Fromme et al.   Molecular Metabolism

Pitpnc1a Regulates Zebrafish Sleep and Wake Behavior through Modulation of Insulin-like Growth Factor Signaling

(2018) Tim G. Ashlin et al.   Cell Reports

Dynamics and energetics of the mammalian phosphatidylinositol transfer protein phospholipid exchange cycle

(2017) Aby Grabon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PITPNC1 Recruits RAB1B to the Golgi Network to Drive Malignant Secretion

(2016) Nils Halberg et al.   CANCER CELL

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

(2016) Bhagirath Chaurasia et al.   Cell Metabolism

Reduction of obesity-associated white adipose tissue inflammation by rosiglitazone is associated with reduced non-alcoholic fatty liver disease in LDLr-deficient mice

(2016) Petra Mulder et al.   Scientific Reports

Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance

(2014) Sarah M. Turpin et al.   Cell Metabolism

14-3-3 protein and ATRAP bind to the soluble class IIB phosphatidylinositol transfer protein RdgBβ at distinct sites

(2012) Shamshad Cockcroft et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phosphatidylinositol Transfer Protein, Cytoplasmic 1 (PITPNC1) Binds and Transfers Phosphatidic Acid

(2012) Kathryn Garner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brown fat and obesity: the next big thing?

(2011) Mark Stephens et al.   CLINICAL ENDOCRINOLOGY

Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?

(2011) Shamshad Cockcroft et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITP  is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum

(2010) N. Carvou et al.   JOURNAL OF CELL SCIENCE

Dynamics of Lipid Transfer by Phosphatidylinositol Transfer Proteins in Cells

(2008) Sadaf Shadan et al.   TRAFFIC