“Structure”-function relationships in eukaryotic transcription factors: The role of intrinsically disordered regions in gene regulation
出版年份 2022 全文链接
标题
“Structure”-function relationships in eukaryotic transcription factors: The role of intrinsically disordered regions in gene regulation
作者
关键词
-
出版物
MOLECULAR CELL
Volume 82, Issue 21, Pages 3970-3984
出版商
Elsevier BV
发表日期
2022-10-19
DOI
10.1016/j.molcel.2022.09.021
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Identification and functional characterization of transcriptional activators in human cells
- (2022) Nader Alerasool et al. MOLECULAR CELL
- Sequence-dependent surface condensation of a pioneer transcription factor on DNA
- (2022) Jose A. Morin et al. Nature Physics
- Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins
- (2022) Rebecca B. Berlow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sequence specificity in DNA binding is mainly governed by association
- (2022) Emil Marklund et al. SCIENCE
- NMR Provides Unique Insight into the Functional Dynamics and Interactions of Intrinsically Disordered Proteins
- (2022) Aldo R. Camacho-Zarco et al. CHEMICAL REVIEWS
- Tuning levels of low-complexity domain interactions to modulate endogenous oncogenic transcription
- (2022) Shasha Chong et al. MOLECULAR CELL
- Prediction of histone post-translational modification patterns based on nascent transcription data
- (2022) Zhong Wang et al. NATURE GENETICS
- Evolution of binding preferences among whole-genome duplicated transcription factors
- (2022) Tamar Gera et al. eLife
- A conceptual framework for understanding phase separation and addressing open questions and challenges
- (2022) Tanja Mittag et al. MOLECULAR CELL
- Conformational buffering underlies functional selection in intrinsically disordered protein regions
- (2022) Nicolás S. González-Foutel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions
- (2022) Mrityunjoy Kar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations linked to neurological disease enhance self-association of low-complexity protein sequences
- (2022) Xiaoming Zhou et al. SCIENCE
- Transcription factors perform a 2-step search of the nucleus
- (2022) Max Valentín Staller GENETICS
- Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator
- (2021) Adrian L Sanborn et al. eLife
- On the roles of intrinsically disordered proteins and regions in cell communication and signaling
- (2021) Sarah E. Bondos et al. Cell Communication and Signaling
- Quantification of Conformational Entropy Unravels Effect of Disordered Flanking Region in Coupled Folding and Binding
- (2021) Frederik Friis Theisen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Spatiotemporal coordination of transcription preinitiation complex assembly in live cells
- (2021) Vu Q. Nguyen et al. MOLECULAR CELL
- Altering transcription factor binding reveals comprehensive transcriptional kinetics of a basic gene
- (2021) Achim P Popp et al. NUCLEIC ACIDS RESEARCH
- The transcription factor activity gradient (TAG) model: contemplating a contact-independent mechanism for enhancer–promoter communication
- (2021) Jonathan P. Karr et al. GENES & DEVELOPMENT
- Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation
- (2020) Fabian Erdel et al. MOLECULAR CELL
- Intrinsic disorder controls two functionally distinct dimers of the master transcription factor PU.1
- (2020) Suela Xhani et al. Science Advances
- Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties
- (2020) Gregory L. Dignon et al. Annual Review of Physical Chemistry
- Hydropathy Patterning Complements Charge Patterning to Describe Conformational Preferences of Disordered Proteins
- (2020) Wenwei Zheng et al. Journal of Physical Chemistry Letters
- Dynamics of genetic variation in transcription factors and its implications for the evolution of regulatory networks in Bacteria
- (2020) Farhan Ali et al. NUCLEIC ACIDS RESEARCH
- Intrinsically Disordered Regions Direct Transcription Factor In Vivo Binding Specificity
- (2020) Sagie Brodsky et al. MOLECULAR CELL
- Index and biological spectrum of human DNase I hypersensitive sites
- (2020) Wouter Meuleman et al. NATURE
- Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility
- (2020) Elizabeth Eck et al. eLife
- Live‐cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting
- (2019) Benjamin T Donovan et al. EMBO JOURNAL
- Negative reciprocity, not ordered assembly, underlies the interaction of Sox2 and Oct4 on DNA
- (2019) John W Biddle et al. eLife
- Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation
- (2019) David Trombley McSwiggen et al. eLife
- Low-Affinity Binding Sites and the Transcription Factor Specificity Paradox in Eukaryotes
- (2019) Judith F. Kribelbauer et al. Annual Review of Cell and Developmental Biology
- Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain
- (2019) Anastasia C. Murthy et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences
- (2019) David T. McSwiggen et al. GENES & DEVELOPMENT
- Guided nuclear exploration increases CTCF target search efficiency
- (2019) Anders S. Hansen et al. Nature Chemical Biology
- A Solid-State Conceptualization of Information Transfer from Gene to Message to Protein
- (2018) Masato Kato et al. Annual Review of Biochemistry
- The Molecular Origin of Enthalpy/Entropy Compensation in Biomolecular Recognition
- (2018) Jerome M. Fox et al. Annual Review of Biophysics
- Collapse Transitions of Proteins and the Interplay Among Backbone, Sidechain, and Solvent Interactions
- (2018) Alex S. Holehouse et al. Annual Review of Biophysics
- Relationship of Sequence and Phase Separation in Protein Low-Complexity Regions
- (2018) Erik W. Martin et al. BIOCHEMISTRY
- P-Bodies: Composition, Properties, and Functions
- (2018) Yang Luo et al. BIOCHEMISTRY
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Visualizing transcription factor dynamics in living cells
- (2018) Zhe Liu et al. JOURNAL OF CELL BIOLOGY
- Imaging dynamic and selective low-complexity domain interactions that control gene transcription
- (2018) Shasha Chong et al. SCIENCE
- Tuning the dynamic range of bacterial promoters regulated by ligand-inducible transcription factors
- (2018) Ye Chen et al. Nature Communications
- Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex
- (2018) Lisa M. Tuttle et al. Cell Reports
- Extreme disorder in an ultrahigh-affinity protein complex
- (2018) Alessandro Borgia et al. NATURE
- Transcriptional Regulatory Circuits: Predicting Numbers from Alphabets
- (2018) Harold D. Kim et al. SCIENCE
- Transcription factor dimerization activates the p300 acetyltransferase
- (2018) Esther Ortega et al. NATURE
- Dense Bicoid hubs accentuate binding along the morphogen gradient
- (2017) Mustafa Mir et al. GENES & DEVELOPMENT
- Hypersensitive termination of the hypoxic response by a disordered protein switch
- (2017) Rebecca B. Berlow et al. NATURE
- Facilitated dissociation of transcription factors from single DNA binding sites
- (2017) Ramsey I. Kamar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
- (2017) Jacob P. Brady et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of transcriptional activity by design of charge patterning in the intrinsically disordered RAM region of the Notch receptor
- (2017) Kathryn P. Sherry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-Molecule FRET Spectroscopy and the Polymer Physics of Unfolded and Intrinsically Disordered Proteins
- (2016) Benjamin Schuler et al. Annual Review of Biophysics
- Coexisting Liquid Phases Underlie Nucleolar Subcompartments
- (2016) Marina Feric et al. CELL
- Single molecule tracking of Ace1p inSaccharomyces cerevisiaedefines a characteristic residence time for non-specific interactions of transcription factors with chromatin
- (2016) David A. Ball et al. NUCLEIC ACIDS RESEARCH
- Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein
- (2016) Alexander S. Krois et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Real-time imaging of Huntingtin aggregates diverting target search and gene transcription
- (2016) Li Li et al. eLife
- A dynamic mode of mitotic bookmarking by transcription factors
- (2016) Sheila S Teves et al. eLife
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- Temporal Hierarchy of Gene Expression Mediated by Transcription Factor Binding Affinity and Activation Dynamics
- (2015) Rong Gao et al. mBio
- Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
- (2014) Jiji Chen et al. CELL
- Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain
- (2014) Grzegorz Popowicz et al. CELL CYCLE
- Classification of Intrinsically Disordered Regions and Proteins
- (2014) Robin van der Lee et al. CHEMICAL REVIEWS
- Extended String Binding Mode of the Phosphorylated Transactivation Domain of Tumor Suppressor p53
- (2014) Masahiko Okuda et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Direct measurement of transcription factor dissociation excludes a simple operator occupancy model for gene regulation
- (2014) Petter Hammar et al. NATURE GENETICS
- Regulation of transcription factor activity by interconnected post-translational modifications
- (2014) Theresa M. Filtz et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
- (2013) R. K. Das et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A decade and a half of protein intrinsic disorder: Biology still waits for physics
- (2013) Vladimir N. Uversky PROTEIN SCIENCE
- Why Transcription Factor Binding Sites Are Ten Nucleotides Long
- (2012) A. J. Stewart et al. GENETICS
- Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy
- (2012) H. Hofmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail
- (2012) John P. Rowell et al. STRUCTURE
- Transcriptional Regulation inSaccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and Coactivators
- (2011) Steven Hahn et al. GENETICS
- The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex
- (2011) Peter S. Brzovic et al. MOLECULAR CELL
- Predicting promoter activities of primary human DNA sequences
- (2011) Takuma Irie et al. NUCLEIC ACIDS RESEARCH
- The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding
- (2011) Xiao-Yong Li et al. GENOME BIOLOGY
- CYCLINg through transcription: Post-translational modifications of P-TEFb regulate transcription elongation
- (2010) Sungyoo Cho et al. CELL CYCLE
- Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA
- (2010) J. S. Graham et al. NUCLEIC ACIDS RESEARCH
- Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells
- (2010) Y. Taniguchi et al. SCIENCE
- Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains
- (2009) Jonathan M Wojciak et al. EMBO JOURNAL
- Different gene regulation strategies revealed by analysis of binding motifs
- (2009) Zeba Wunderlich et al. TRENDS IN GENETICS
- Multiple Intrinsically Disordered Sequences Alter DNA Binding by the Homeodomain of theDrosophilaHox Protein Ultrabithorax
- (2008) Ying Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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