Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain
出版年份 2019 全文链接
标题
Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain
作者
关键词
-
出版物
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 26, Issue 7, Pages 637-648
出版商
Springer Science and Business Media LLC
发表日期
2019-07-02
DOI
10.1038/s41594-019-0250-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation
- (2019) Brian Tsang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
- (2018) Mario Hofweber et al. CELL
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Tau protein liquid–liquid phase separation can initiate tau aggregation
- (2018) Susanne Wegmann et al. EMBO JOURNAL
- Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation
- (2018) Veronica H. Ryan et al. MOLECULAR CELL
- A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation
- (2018) Thomas R. Peskett et al. MOLECULAR CELL
- Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation
- (2018) Feng Luo et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- mRNA structure determines specificity of a polyQ-driven phase separation
- (2018) Erin M. Langdon et al. SCIENCE
- Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
- (2018) Michael P. Hughes et al. SCIENCE
- Phase separation of a yeast prion protein promotes cellular fitness
- (2018) Titus M. Franzmann et al. SCIENCE
- Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation
- (2018) Feng Luo et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity
- (2018) Elke Bogaert et al. Cell Reports
- Sequence determinants of protein phase behavior from a coarse-grained model
- (2018) Gregory L. Dignon et al. PLoS Computational Biology
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation
- (2018) Robert McCoy Vernon et al. eLife
- Relation between single-molecule properties and phase behavior of intrinsically disordered proteins
- (2018) Gregory L. Dignon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs
- (2017) Yuan Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles
- (2017) Ming-Tzo Wei et al. Nature Chemistry
- Direct observation of structure and dynamics during phase separation of an elastomeric protein
- (2017) Sean E. Reichheld et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
- (2017) Jacob P. Brady et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phase separation in biology; functional organization of a higher order
- (2016) Diana M. Mitrea et al. Cell Communication and Signaling
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- All characteristic Raman markers of tyrosine and tyrosinate originate from phenol ring fundamental vibrations
- (2015) Belén Hernández et al. JOURNAL OF RAMAN SPECTROSCOPY
- Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
- (2015) Yuan Lin et al. MOLECULAR CELL
- Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
- (2015) Kathleen A. Burke et al. MOLECULAR CELL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
- (2015) Tetsuro Murakami et al. NEURON
- NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy
- (2014) Woonghee Lee et al. BIOINFORMATICS
- Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association
- (2014) Robert B. Best et al. Journal of Chemical Theory and Computation
- Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains
- (2013) Ilmin Kwon et al. CELL
- The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
- (2012) Oliver D. King et al. BRAIN RESEARCH
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- The Hydrogen-Bonding Ability of the Amino Acid Glutamine Revealed by Neutron Diffraction Experiments
- (2012) N. H. Rhys et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy
- (2012) Nicolas L Fawzi et al. Nature Protocols
- Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR
- (2011) Nicolas L. Fawzi et al. NATURE
- Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
- (2011) C. P. Brangwynne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A yeast functional screen predicts new candidate ALS disease genes
- (2011) J. Couthouis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS
- (2011) Zhihui Sun et al. PLOS BIOLOGY
- FUS/TLS forms cytoplasmic aggregates, inhibits cell growth and interacts with TDP-43 in a yeast model of amyotrophic lateral sclerosis
- (2011) Dmitry Kryndushkin et al. Protein & Cell
- Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy
- (2011) Kazuo Fushimi et al. Protein & Cell
- Label-Free Cellular Imaging by Broadband Coherent Anti-Stokes Raman Scattering Microscopy
- (2010) Sapun H. Parekh et al. BIOPHYSICAL JOURNAL
- Kinetics of Amyloid β Monomer-to-Oligomer Exchange by NMR Relaxation
- (2010) Nicolas L. Fawzi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enhanced Sampling in the Well-Tempered Ensemble
- (2010) M. Bonomi et al. PHYSICAL REVIEW LETTERS
- Broadband CARS spectral phase retrieval using a time-domain Kramers–Kronig transform
- (2009) Yuexin Liu et al. OPTICS LETTERS
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
- (2009) C. P. Brangwynne et al. SCIENCE
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- General purpose molecular dynamics simulations fully implemented on graphics processing units
- (2008) Joshua A. Anderson et al. JOURNAL OF COMPUTATIONAL PHYSICS
- Effects of Hofmeister Anions on the Phase Transition Temperature of Elastin-like Polypeptides
- (2008) Younhee Cho et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Well-Tempered Metadynamics: A Smoothly Converging and Tunable Free-Energy Method
- (2008) Alessandro Barducci et al. PHYSICAL REVIEW LETTERS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started