An in vitro and in silico α-amylase/α-glucosidase/protein tyrosine phosphatase 1 beta & radical scavenging profiling of the 3,5,7-tricarbo substituted 1H-indazoles

Short-Term versus Long-Term Culture of A549 Cells for Evaluating the Effects of Lipopolysaccharide on Oxidative Stress, Surfactant Proteins and Cathelicidin LL-37

(2020) Zuzana Nova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phytopharmacological Strategies in the Management of Type 2 Diabetes Mellitus

(2020) Ana M. Duarte et al.   Foods

Synthesis, α-glucosidase inhibition and antioxidant activity of the 7-carbo–substituted 5-bromo-3-methylindazoles

(2020) Malose J. Mphahlele et al.   BIOORGANIC CHEMISTRY

Multifunctional isoxazolidine derivatives as α-amylase and α-glucosidase inhibitors

(2020) Ameni Ghabi et al.   BIOORGANIC CHEMISTRY

Type 2 Diabetes Mellitus: A Review of Multi-Target Drugs

(2020) Angelica Artasensi et al.   MOLECULES

Insight into the PTP1B Inhibitory Activity of Arylbenzofurans: An In Vitro and In Silico Study

(2019) Srijan Shrestha et al.   MOLECULES

Relationship Between Oxidative Stress, ER Stress, and Inflammation in Type 2 Diabetes: The Battle Continues

(2019) Burgos-Morón et al.   Journal of Clinical Medicine

Synthesis, Structural Studies, and α-Glucosidase Inhibitory, Antidiabetic, and Antioxidant Activities of 2,3-Dihydroquinazolin-4(1H)-ones Derived from Pyrazol-4-carbaldehyde and Anilines

(2019) Alireza Barmak et al.   ACS Omega

Synthesis and molecular docking studies of imines as α-glucosidase and α-amylase inhibitors

(2019) Analy Aispuro-Pérez et al.   BIOORGANIC CHEMISTRY

Computational Insight into Dengue Virus NS2B-NS3 Protease Inhibition: A Combined Ligand- and Structure-Based Approach

(2018) Junning Chen et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Enzymes inhibitors from natural sources with antidiabetic activity: A review

(2018) Fiaz Alam et al.   PHYTOTHERAPY RESEARCH

Indazole-based ligands for estrogen-related receptor α as potential anti-diabetic agents

(2017) Raymond J. Patch et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A novel protein tyrosine phosphatase 1B inhibitor with therapeutic potential for insulin resistance

(2016) Xiaolin Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fluorine-containing indazoles: Synthesis and biological activity

(2016) Galina N. Lipunova et al.   JOURNAL OF FLUORINE CHEMISTRY

Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

(2016) Vibha Rani et al.   LIFE SCIENCES

Advanced glycation End-products (AGEs): an emerging concern for processed food industries

(2015) Chetan Sharma et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Small Molecules as Potent Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors Documented in Patents from 2009 to 2013

(2015) Li-Jun Wang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

The Mechanism of Allosteric Inhibition of Protein Tyrosine Phosphatase 1B

(2014) Shuai Li et al.   PLoS One

Binding Mechanism and Synergetic Effects of Xanthone Derivatives as Noncompetitive α-Glucosidase Inhibitors: A Theoretical and Experimental Study

(2013) Yan Liu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Halogen bonding for rational drug design and new drug discovery

(2012) Yunxiang Lu et al.   Expert Opinion on Drug Discovery

Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology

(2012) Rainer Wilcken et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): Synthesis and biological evaluation

(2009) Rosa M. Claramunt et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Molecular dynamics studies on the interactions of PTP1B with inhibitors: from the first phosphate-binding site to the second one

(2009) Jing-Fang Wang et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: Particular potency of 1H-indazole-7-carbonitrile

(2008) Betty Cottyn et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS