标题
Halogen bonding for rational drug design and new drug discovery
作者
关键词
-
出版物
Expert Opinion on Drug Discovery
Volume 7, Issue 5, Pages 375-383
出版商
Informa Healthcare
发表日期
2012-03-30
DOI
10.1517/17460441.2012.678829
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ditopic Ion Transport Systems: Anion-π Interactions and Halogen Bonds at Work
- (2011) Andreas Vargas Jentzsch et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Putting Anion-π Interactions Into Perspective
- (2011) Antonio Frontera et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Aromatic Rings in Chemical and Biological Recognition: Energetics and Structures
- (2011) Laura M. Salonen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Halogen bonding in halocarbon–protein complexes: a structural survey
- (2011) Emilio Parisini et al. CHEMICAL SOCIETY REVIEWS
- Kinase Inhibition that Hinges on Halogen Bonds
- (2011) Stephan K. Grant et al. CHEMISTRY & BIOLOGY
- Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing
- (2011) Oleg Fedorov et al. CHEMISTRY & BIOLOGY
- Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments
- (2011) Leo A. Hardegger et al. ChemMedChem
- Strength and Character of Halogen Bonds in Protein–Ligand Complexes
- (2011) Kevin E. Riley et al. CRYSTAL GROWTH & DESIGN
- Fluorine-Centered Halogen Bonding: A Factor in Recognition Phenomena and Reactivity
- (2011) Pierangelo Metrangolo et al. CRYSTAL GROWTH & DESIGN
- Assaying the Energies of Biological Halogen Bonds
- (2011) Megan Carter et al. CRYSTAL GROWTH & DESIGN
- The fluorine atom as a halogen bond donor, viz. a positive site
- (2011) Pierangelo Metrangolo et al. CRYSTENGCOMM
- Effects of solvent on weak halogen bonds: Density functional theory calculations
- (2011) Yunxiang Lu et al. INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY
- Performance Assessment of Semiempirical Molecular Orbital Methods in Describing Halogen Bonding: Quantum Mechanical and Quantum Mechanical/Molecular Mechanical-Molecular Dynamics Study
- (2011) Mahmoud A. A. Ibrahim Journal of Chemical Information and Modeling
- Molecular mechanical study of halogen bonding in drug discovery
- (2011) Mahmoud A. A. Ibrahim JOURNAL OF COMPUTATIONAL CHEMISTRY
- Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors
- (2011) Zhijian Xu et al. JOURNAL OF MEDICINAL CHEMISTRY
- How Does Halogen Bonding Behave in Solution? A Theoretical Study Using Implicit Solvation Model
- (2011) Yunxiang Lu et al. JOURNAL OF PHYSICAL CHEMISTRY A
- Semiempirical Quantum Mechanical Method PM6-DH2X Describes the Geometry and Energetics of CK2-Inhibitor Complexes Involving Halogen Bonds Well, While the Empirical Potential Fails
- (2011) Petr Dobeš et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Anion Receptors Composed of Hydrogen- and Halogen-Bond Donor Groups: Modulating Selectivity With Combinations of Distinct Noncovalent Interactions
- (2011) Michael G. Chudzinski et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Halogen bonding in ligand–receptor systems in the framework of classical force fields
- (2011) Stefano Rendine et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- A Tridentate Halogen-Bonding Receptor for Tight Binding of Halide Anions
- (2010) Mohammed G. Sarwar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions
- (2010) Leo A. Hardegger et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Directional Weak Intermolecular Interactions: σ-Hole Bonding
- (2010) Jane S. Murray et al. AUSTRALIAN JOURNAL OF CHEMISTRY
- Halogen bonding: a general route in anion recognition and coordination
- (2010) Gabriella Cavallo et al. CHEMICAL SOCIETY REVIEWS
- Halogen Bonds Form the Basis for Selective P-TEFb Inhibition by DRB
- (2010) Sonja Baumli et al. CHEMISTRY & BIOLOGY
- Halogen Atoms in the Modern Medicinal Chemistry: Hints for the Drug Design
- (2010) Marcelo Hernandes et al. CURRENT DRUG TARGETS
- A Medicinal Chemist’s Guide to Molecular Interactions
- (2010) Caterina Bissantz et al. JOURNAL OF MEDICINAL CHEMISTRY
- The halogen bond: an interim perspective
- (2010) Anthony C. Legon PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Nonbonding interactions of organic halogens in biological systems: implications for drug discovery and biomolecular design
- (2010) Yunxiang Lu et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Halogen bonding: an electrostatically-driven highly directional noncovalent interaction
- (2010) Peter Politzer et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Evaluating the Potential for Halogen Bonding in the Oxyanion Hole of Ketosteroid Isomerase Using Unnatural Amino Acid Mutagenesis
- (2009) Daniel A. Kraut et al. ACS Chemical Biology
- Evidence for CCl/CBr⋅⋅⋅π Interactions as an Important Contribution to Protein-Ligand Binding Affinity
- (2009) Hans Matter et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Protein Kinase CK2 in Health and Disease
- (2009) R. Battistutta CELLULAR AND MOLECULAR LIFE SCIENCES
- Halogen bonding in metal–organic–supramolecular networks
- (2009) Roberta Bertani et al. COORDINATION CHEMISTRY REVIEWS
- Halogen bonding: Recent advances
- (2009) Marc Fourmigué CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE
- Role of Halogen Bonds in Thyroid Hormone Receptor Selectivity: Pharmacophore-Based 3D-QSSR Studies
- (2009) Napoleão F. Valadares et al. Journal of Chemical Information and Modeling
- Halogen BondingA Novel Interaction for Rational Drug Design?
- (2009) Yunxiang Lu et al. JOURNAL OF MEDICINAL CHEMISTRY
- C−X···H Contacts in Biomolecular Systems: How They Contribute to Protein−Ligand Binding Affinity
- (2009) Yunxiang Lu et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Halogen bonds as orthogonal molecular interactions to hydrogen bonds
- (2009) Andrea Regier Voth et al. Nature Chemistry
- Nonporous Organic Solids Capable of Dynamically Resolving Mixtures of Diiodoperfluoroalkanes
- (2009) P. Metrangolo et al. SCIENCE
- Halogen Bonding in Supramolecular Chemistry
- (2008) Pierangelo Metrangolo et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Combining metals with halogen bonds
- (2008) Lee Brammer et al. CRYSTENGCOMM
- Halogen bonded supramolecular complexes and networks
- (2008) Kari Rissanen CRYSTENGCOMM
- Design, Structure−Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors⊥‡
- (2008) Yan Shi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Halogenated Benzenes Bound within a Non-polar Cavity in T4 Lysozyme Provide Examples of I⋯S and I⋯Se Halogen-bonding
- (2008) Lijun Liu et al. JOURNAL OF MOLECULAR BIOLOGY
- Expansion of the σ-hole concept
- (2008) Jane S. Murray et al. JOURNAL OF MOLECULAR MODELING
- CHEMISTRY: Halogen Versus Hydrogen
- (2008) P. Metrangolo et al. SCIENCE
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