SGLT2 inhibitors improve kidney function and morphology by regulating renal metabolic reprogramming in mice with diabetic kidney disease
出版年份 2022 全文链接
标题
SGLT2 inhibitors improve kidney function and morphology by regulating renal metabolic reprogramming in mice with diabetic kidney disease
作者
关键词
-
出版物
Journal of Translational Medicine
Volume 20, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-09-15
DOI
10.1186/s12967-022-03629-8
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Blocking connexin 43 and its promotion of ATP release from renal tubular epithelial cells ameliorates renal fibrosis
- (2022) Huzi Xu et al. Cell Death & Disease
- KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease
- (2021) Yutaro Mori et al. Cell Metabolism
- Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly
- (2021) Christopher F. Bennett et al. Nature Chemical Biology
- DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
- (2021) Juan Zhang et al. iScience
- MHC class II in renal tubules plays an essential role in renal fibrosis
- (2021) Yunfeng Zhou et al. Cellular & Molecular Immunology
- Characteristics of Ventricular Electrophysiological Substrates in Metabolic Mice Treated with Empagliflozin
- (2021) Shih-Jie Jhuo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Impaired Nicotinamide Adenine Dinucleotide Biosynthesis in the Kidney of Chronic Kidney Disease
- (2021) Xinhui Liu et al. Frontiers in Physiology
- Metabolic Changes and Oxidative Stress in Diabetic Kidney Disease
- (2021) Midori Sakashita et al. Antioxidants
- NAD+ Homeostasis in Diabetic Kidney Disease
- (2021) Jing Xu et al. Frontiers in Medicine
- Lysine 2-hydroxyisobutyrylation proteomics reveals protein modification alteration in the actin cytoskeleton pathway of oral squamous cell carcinoma
- (2021) Zeyu Zhang et al. Journal of Proteomics
- A low aromatic amino-acid diet improves renal function and prevent kidney fibrosis in mice with chronic kidney disease
- (2021) Christophe Barba et al. Scientific Reports
- Mitochondria in Diabetic Kidney Disease
- (2021) Amna Ayesha Ahmad et al. Cells
- Metabolomic Profiling of Amino Acids in Human Plasma Distinguishes Diabetic Kidney Disease From Type 2 Diabetes Mellitus
- (2021) Chunyu Zhou et al. Frontiers in Medicine
- d-Amino acids and kidney diseases
- (2020) Tomonori Kimura et al. Clinical and Experimental Nephrology
- Serum hepcidin, the hepcidin/ferritin ratio and the risk of type 2 diabetes: a systematic review and meta-analysis
- (2020) Nahid Karamzad et al. CURRENT MEDICINAL CHEMISTRY
- Cell junction proteins: Crossing the glomerular filtration barrier in diabetic nephropathy
- (2020) Aziz Eftekhari et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- SGLT2 Inhibitor Empagliflozin and DPP4 Inhibitor Linagliptin Reactivate Glomerular Autophagy in db/db Mice, a Model of Type 2 Diabetes
- (2020) Anton I. Korbut et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The role of renal hypoxia in the pathogenesis of diabetic kidney disease: a promising target for newer renoprotective agents including SGLT2 inhibitors?
- (2020) Anne C. Hesp et al. KIDNEY INTERNATIONAL
- Sodium–glucose cotransporter 2 inhibition suppresses HIF-1α-mediated metabolic switch from lipid oxidation to glycolysis in kidney tubule cells of diabetic mice
- (2020) Ting Cai et al. Cell Death & Disease
- Metabolic Dynamics and Prediction of Gestational Age and Time to Delivery in Pregnant Women
- (2020) Liang Liang et al. CELL
- SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition
- (2020) Issei Tomita et al. Cell Metabolism
- SGLT2 inhibitors: mechanisms of cardiovascular benefit beyond glycaemic control
- (2020) Martin R. Cowie et al. Nature Reviews Cardiology
- Conversion of extracellular ATP into adenosine: a master switch in renal health and disease
- (2020) Karen M. Dwyer et al. Nature Reviews Nephrology
- Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors
- (2020) Aviram Kogot-Levin et al. Cell Reports
- The genetic map of diabetic nephropathy: evidence from a systematic review and meta-analysis of genetic association studies
- (2020) Maria Tziastoudi et al. Clinical Kidney Journal
- Canagliflozin ameliorates renal oxidative stress and inflammation by stimulating AMPK–Akt–eNOS pathway in the isoprenaline-induced oxidative stress model
- (2020) Raquibul Hasan et al. Scientific Reports
- Purinergic signalling in the kidney: In physiology and disease
- (2020) Marie-Louise T. Monaghan et al. BIOCHEMICAL PHARMACOLOGY
- Oxidative Storm Induced by Tryptophan Metabolites: Missing Link between Atherosclerosis and Chronic Kidney Disease
- (2020) Iwona Kwiatkowska et al. Oxidative Medicine and Cellular Longevity
- Angiotensin-(3–4) normalizes blood pressure, decreases Na+ and energy intake, but preserves urinary Na+ excretion in overweight hypertensive rats
- (2020) Rafael Luzes et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Analysis from the EMPA-REG OUTCOME® trial indicate empagliflozin may assist in preventing the progression of chronic kidney disease in patients with type 2 diabetes irrespective of medications that alter intrarenal hemodynamics
- (2019) Gert J. Mayer et al. KIDNEY INTERNATIONAL
- WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition
- (2019) Pouya Saeedi et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Metabolomics analysis elucidates unique influences on purine / pyrimidine metabolism by xanthine oxidoreductase inhibitors in a rat model of renal ischemia-reperfusion injury
- (2019) Takashi Tani et al. MOLECULAR MEDICINE
- NAD+ homeostasis in renal health and disease
- (2019) Kenneth M. Ralto et al. Nature Reviews Nephrology
- Testosterone Increases the Expression and Phosphorylation of AMP kinase α in Men with Hypogonadism and Type 2 Diabetes
- (2019) Husam Ghanim et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The oral hypoxia-inducible factor prolyl hydroxylase inhibitor enarodustat counteracts alterations in renal energy metabolism in the early stages of diabetic kidney disease
- (2019) Sho Hasegawa et al. KIDNEY INTERNATIONAL
- SGLT2 inhibition via dapagliflozin improves generalized vascular dysfunction and alters the gut microbiota in type 2 diabetic mice
- (2018) Dustin M. Lee et al. Cardiovascular Diabetology
- Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease
- (2018) Allison Agus et al. Cell Host & Microbe
- Quantitative Analysis of NAD Synthesis-Breakdown Fluxes
- (2018) Ling Liu et al. Cell Metabolism
- Asymmetric dimethylarginine (ADMA) as an important risk factor for the increased cardiovascular diseases and heart failure in chronic kidney disease
- (2018) Xiaohong Liu et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- High Basolateral Glucose Increases Sodium-Glucose Cotransporter 2 and Reduces Sirtuin-1 in Renal Tubules through Glucose Transporter-2 Detection
- (2018) Hiroyuki Umino et al. Scientific Reports
- Intensified multifactorial intervention in type 2 diabetics with microalbuminuria leads to long-term renal benefits
- (2017) Jens Oellgaard et al. KIDNEY INTERNATIONAL
- Adenosine signaling in diabetes mellitus and associated cardiovascular and renal complications
- (2017) Maria Peleli et al. MOLECULAR ASPECTS OF MEDICINE
- Daily Intake of Grape Powder Prevents the Progression of Kidney Disease in Obese Type 2 Diabetic ZSF1 Rats
- (2017) Salwa Almomen et al. Nutrients
- Increased plasma serotonin metabolite 5-hydroxyindole acetic acid concentrations are associated with impaired systolic and late diastolic forward flows during cardiac cycle and elevated resistive index at popliteal artery and renal insufficiency in type 2 diabetic patients with microalbuminuria
- (2016) Jun Saito et al. ENDOCRINE JOURNAL
- Clinical Manifestations of Kidney Disease Among US Adults With Diabetes, 1988-2014
- (2016) Maryam Afkarian et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes
- (2016) Christoph Wanner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chiral amino acid metabolomics for novel biomarker screening in the prognosis of chronic kidney disease
- (2016) Tomonori Kimura et al. Scientific Reports
- Adenosine A2a receptor stimulation prevents proteinuria in diabetic rats by promoting an anti-inflammatory phenotype without affecting oxidative stress
- (2015) P. Persson et al. Acta Physiologica
- Hypoxia Inhibits Cavin-1 and Cavin-2 Expression and Down-Regulates Caveolae in Adipocytes
- (2015) Claire Regazzetti et al. ENDOCRINOLOGY
- Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes
- (2015) Gregory F. Oxenkrug MOLECULAR NEUROBIOLOGY
- Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
- (2015) Bernard Zinman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mind the gap: connexins and cell–cell communication in the diabetic kidney
- (2014) Claire E. Hills et al. DIABETOLOGIA
- Cystatin C versus Creatinine in Determining Risk Based on Kidney Function
- (2013) Michael G. Shlipak et al. NEW ENGLAND JOURNAL OF MEDICINE
- Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits
- (2013) Gordon F. Rushworth et al. PHARMACOLOGY & THERAPEUTICS
- Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction
- (2012) JingXian Fang et al. BIOSCIENCE REPORTS
- Plasma Prolylcarboxypeptidase (Angiotensinase C) Is Increased in Obesity and Diabetes Mellitus and Related to Cardiovascular Dysfunction
- (2012) S. Xu et al. CLINICAL CHEMISTRY
- Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C
- (2012) Lesley A. Inker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Angiotensin-(3–4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway
- (2012) Flavia Axelband et al. REGULATORY PEPTIDES
- Role of oxidative stress in diabetes-mediated vascular dysfunction: Unifying hypothesis of diabetes revisited
- (2012) Stephen W. Schaffer et al. VASCULAR PHARMACOLOGY
- Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway
- (2010) A. A. Khutornenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of renal arteriolar tone by adenosine: novel role for type 2 receptors
- (2009) Tracy D. Bell et al. KIDNEY INTERNATIONAL
- Coordinate suppression of Sdpr and Fhl1 expression in tumors of the breast, kidney, and prostate
- (2008) Xun Li et al. CANCER SCIENCE
- ACE Gene Polymorphism and Losartan Treatment in Type 2 Diabetic Patients With Nephropathy
- (2008) H.-H. Parving et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started