Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus–Derived CD8+T Cell Epitopes and Host MHC

MERS-CoV spike protein: Targets for vaccines and therapeutics

(2016) Qihui Wang et al.   ANTIVIRAL RESEARCH

Vaccines for the prevention against the threat of MERS-CoV

(2016) Lanying Du et al.   Expert Review of Vaccines

Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles

(2016) Shugang Yao et al.   JOURNAL OF IMMUNOLOGY

Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I

(2016) Jin Xiao et al.   JOURNAL OF IMMUNOLOGY

The recent ancestry of Middle East respiratory syndrome coronavirus in Korea has been shaped by recombination

(2016) Jin Il Kim et al.   Scientific Reports

Comparative and kinetic analysis of viral shedding and immunological responses in MERS patients representing a broad spectrum of disease severity

(2016) Chan-Ki Min et al.   Scientific Reports

Viral Shedding and Antibody Response in 37 Patients With Middle East Respiratory Syndrome Coronavirus Infection

(2015) Victor M. Corman et al.   CLINICAL INFECTIOUS DISEASES

Systemic and mucosal immunity in mice elicited by a single immunization with human adenovirus type 5 or 41 vector-based vaccines carrying the spike protein of Middle East respiratory syndrome coronavirus

(2015) Xiaojuan Guo et al.   IMMUNOLOGY

Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide

(2015) Chihiro Motozono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Frequency, Private Specificity, and Cross-Reactivity of Preexisting Hepatitis C Virus (HCV)-Specific CD8+T Cells in HCV-Seronegative Individuals: Implications for Vaccine Responses

(2015) Shihong Zhang et al.   JOURNAL OF VIROLOGY

Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein

(2015) Asisa Volz et al.   JOURNAL OF VIROLOGY

MERS in South Korea and China: a potential outbreak threat?

(2015) Shuo Su et al.   LANCET

Origin and Possible Genetic Recombination of the Middle East Respiratory Syndrome Coronavirus from the First Imported Case in China: Phylogenetics and Coalescence Analysis

(2015) Yanqun Wang et al.   mBio

Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge

(2015) Jiaming Lan et al.   EBioMedicine

Current advancements and potential strategies in the development of MERS-CoV vaccines

(2014) Naru Zhang et al.   Expert Review of Vaccines

T Cell Responses to Whole SARS Coronavirus in Humans

(2014) C. K.-f. Li et al.   JOURNAL OF IMMUNOLOGY

Tailoring Subunit Vaccine Immunity with Adjuvant Combinations and Delivery Routes Using the Middle East Respiratory Coronavirus (MERS-CoV) Receptor-Binding Domain as an Antigen

(2014) Jiaming Lan et al.   PLoS One

Rapid generation of a mouse model for Middle East respiratory syndrome

(2014) Jincun Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes

(2014) Lu Sun et al.   Protein & Cell

Conserved epitopes dominate cross-CD8+T-cell responses against influenza A H1N1 virus among Asian populations

(2013) Jun Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Peptide Modulation of Class I Major Histocompatibility Complex Protein Molecular Flexibility and the Implications for Immune Recognition

(2013) William F. Hawse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preemptive priming readily overcomes structure-based mechanisms of virus escape

(2013) S. A. Valkenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel human coronavirus: Middle East respiratory syndrome human coronavirus

(2013) HeYuan Geng et al.   Science China-Life Sciences

A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned

(2012) Stephanie Gras et al.   IMMUNOLOGICAL REVIEWS

Structural and dynamic control of T-cell receptor specificity, cross-reactivity, and binding mechanism

(2012) Brian M. Baker et al.   IMMUNOLOGICAL REVIEWS

Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals

(2012) J. Liu et al.   JOURNAL OF VIROLOGY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Revival of the identification of cytotoxic T-lymphocyte epitopes for immunological diagnosis, therapy and vaccine development

(2011) Jun Liu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility

(2011) Francis K. Insaidoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Distinct Conformations of a Rinderpest Virus Epitope Presented by Bovine Major Histocompatibility Complex Class I N*01801: a Host Strategy To Present Featured Peptides

(2011) X. Li et al.   JOURNAL OF VIROLOGY

Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes

(2011) Shihong Zhang et al.   MOLECULAR IMMUNOLOGY

Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells

(2011) D. Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Acts as a Dominant Immunogen Revealed by a Clustering Region of Novel Functionally and Structurally Defined Cytotoxic T‐Lymphocyte Epitopes

(2010) Jun Liu et al.   JOURNAL OF INFECTIOUS DISEASES

T Cell Responses Are Required for Protection from Clinical Disease and for Virus Clearance in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice

(2010) J. Zhao et al.   JOURNAL OF VIROLOGY

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

(2010) Sophie A. Valkenburg et al.   PLoS Pathogens

T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility

(2009) Oleg Y. Borbulevych et al.   IMMUNITY