Peptide Modulation of Class I Major Histocompatibility Complex Protein Molecular Flexibility and the Implications for Immune Recognition

Structural and dynamic control of T-cell receptor specificity, cross-reactivity, and binding mechanism

(2012) Brian M. Baker et al.   IMMUNOLOGICAL REVIEWS

Conformational variation in structures of classical and non-classical MHCII proteins and functional implications

(2012) Corrie A. Painter et al.   IMMUNOLOGICAL REVIEWS

HELANAL-Plus: a web server for analysis of helix geometry in protein structures

(2012) Prasun Kumar et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

The relation of the X-ray B-factor to protein dynamics: insights from recent dynamic solid-state NMR data

(2012) Detlef Reichert et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Cutting Edge: Evidence for a Dynamically Driven T Cell Signaling Mechanism

(2012) W. F. Hawse et al.   JOURNAL OF IMMUNOLOGY

The role of protein conformational fluctuations in allostery, function, and evolution

(2011) James O. Wrabl et al.   BIOPHYSICAL CHEMISTRY

Influence of inflammation-related changes on conformational characteristics of HLA-B27 subtypes as detected by IR spectroscopy

(2011) Heinz Fabian et al.   FEBS Journal

Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility

(2011) Francis K. Insaidoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics

(2011) O. Y. Borbulevych et al.   JOURNAL OF IMMUNOLOGY

TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms

(2011) O. Y. Borbulevych et al.   JOURNAL OF IMMUNOLOGY

Disparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding Mechanism

(2011) Daniel R. Scott et al.   JOURNAL OF MOLECULAR BIOLOGY

Dynamical Characterization of Two Differentially Disease Associated MHC Class I Proteins in Complex with Viral and Self-Peptides

(2011) Daniele Narzi et al.   JOURNAL OF MOLECULAR BIOLOGY

Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B

(2011) Julian P. Vivian et al.   NATURE

Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange

(2011) C. A. Painter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy

(2011) L. R. Masterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen exchange mass spectrometry: what is it and what can it tell us?

(2010) Sean R. Marcsisin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition

(2010) D. K. Cole et al.   JOURNAL OF IMMUNOLOGY

Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands

(2010) D. D. Boehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

(2010) Peter Csermely et al.   TRENDS IN BIOCHEMICAL SCIENCES

T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility

(2009) Oleg Y. Borbulevych et al.   IMMUNITY

The molecular basis of TCR germline bias for MHC is surprisingly simple

(2009) K Christopher Garcia et al.   NATURE IMMUNOLOGY

Ligand binding to proteins: The binding landscape model

(2009) David W. Miller et al.   PROTEIN SCIENCE

Sending Signals Dynamically

(2009) R. G. Smock et al.   SCIENCE

Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes

(2008) Kathryn M. Armstrong et al.   BIOCHEMICAL JOURNAL

Simulations of a Protein Crystal: Explicit Treatment of Crystallization Conditions Links Theory and Experiment in the Streptavidin−Biotin Complex†

(2008) David S. Cerutti et al.   BIOCHEMISTRY

Molecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell Receptors

(2008) Lu Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HLA-B27 Subtypes Differentially Associated with Disease Exhibit Conformational Differences in Solution

(2007) Heinz Fabian et al.   JOURNAL OF MOLECULAR BIOLOGY